Structure of the myotonic dystrophy type 2 RNA and designed small molecules that reduce toxicity.
about
Structure based approaches for targeting non-coding RNAs with small moleculesApproaches to Validate and Manipulate RNA Targets with Small Molecules in CellsComputational investigation of RNA CUG repeats responsible for myotonic dystrophy 1Modifications to toxic CUG RNAs induce structural stability, rescue mis-splicing in a myotonic dystrophy cell model and reduce toxicity in a myotonic dystrophy zebrafish model.Aberrant RNA homeostasis in amyotrophic lateral sclerosis: potential for new therapeutic targets?Small molecules that target the toxic RNA in myotonic dystrophy type 2.RNA Structures as Mediators of Neurological Diseases and as Drug Targets.On the Applicability of Elastic Network Models for the Study of RNA CUG Trinucleotide Repeat Overexpansion.Controlled dehydration improves the diffraction quality of two RNA crystals.Watson-Crick-like pairs in CCUG repeats: evidence for tautomeric shifts or protonation.Inforna 2.0: A Platform for the Sequence-Based Design of Small Molecules Targeting Structured RNAsIsothermal titration calorimetry of ion-coupled membrane transporters.A toxic RNA catalyzes the in cellulo synthesis of its own inhibitor.RNA mis-splicing in disease.Hypo- and Hyper-Assembly Diseases of RNA-Protein Complexes.Structures of RNA repeats associated with neurological diseases.Faulty RNA splicing: consequences and therapeutic opportunities in brain and muscle disorders.RNA biology of disease-associated microsatellite repeat expansions.Modelling the three-dimensional structure of the right-terminal domain of pospiviroids.RNA-binding proteins in neurodegeneration: mechanisms in aggregate.Using Genome Sequence to Enable the Design of Medicines and Chemical Probes.Automated RNA 3D Structure Prediction with RNAComposer
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P2860
Structure of the myotonic dystrophy type 2 RNA and designed small molecules that reduce toxicity.
description
2013 nî lūn-bûn
@nan
2013 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
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2013年学术文章
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2013年学术文章
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2013年学术文章
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2013年学术文章
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2013年学术文章
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2013年學術文章
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name
Structure of the myotonic dyst ...... olecules that reduce toxicity.
@ast
Structure of the myotonic dyst ...... olecules that reduce toxicity.
@en
type
label
Structure of the myotonic dyst ...... olecules that reduce toxicity.
@ast
Structure of the myotonic dyst ...... olecules that reduce toxicity.
@en
prefLabel
Structure of the myotonic dyst ...... olecules that reduce toxicity.
@ast
Structure of the myotonic dyst ...... olecules that reduce toxicity.
@en
P2093
P2860
P356
P1433
P1476
Structure of the myotonic dyst ...... olecules that reduce toxicity.
@en
P2093
HaJeung Park
Ilyas Yildirim
Jeremy R Lohman
Jessica L Childs-Disney
Lirui Guan
Matthew D Disney
Partha Sarkar
P2860
P304
P356
10.1021/CB4007387
P577
2013-12-16T00:00:00Z