The regulatory SCR-1/5 and cell surface-binding SCR-16/20 fragments of factor H reveal partially folded-back solution structures and different self-associative properties
about
Structural analysis of the C-terminal region (modules 18-20) of complement regulator factor H (FH)Structural basis for engagement by complement factor H of C3b on a self surfaceThe central portion of factor H (modules 10-15) is compact and contains a structurally deviant CCP moduleStructure of complement fragment C3b-factor H and implications for host protection by complement regulatorsSolution Structure of CCP Modules 10–12 Illuminates Functional Architecture of the Complement Regulator, Factor HComplement factor H, vitronectin, and opticin are tyrosine-sulfated proteins of the retinal pigment epitheliumNear-planar solution structures of mannose-binding lectin oligomers provide insight on activation of lectin pathway of complementThe binding of factor H to a complex of physiological polyanions and C3b on cells is impaired in atypical hemolytic uremic syndrome.SCT: a suite of programs for comparing atomistic models with small-angle scattering data.Complement factor H: using atomic resolution structure to illuminate disease mechanisms.Complement control protein factor H: the good, the bad, and the inadequate.Meningococcal disease and the complement system.Zinc binding to the Tyr402 and His402 allotypes of complement factor H: possible implications for age-related macular degeneration.A revised mechanism for the activation of complement C3 to C3b: a molecular explanation of a disease-associated polymorphismEstimation of interdomain flexibility of N-terminus of factor H using residual dipolar couplingsMapping the Complement Factor H-Related Protein 1 (CFHR1):C3b/C3d Interactions.Zinc-induced self-association of complement C3b and Factor H: implications for inflammation and age-related macular degeneration.Experimental approaches for solution X-ray scattering and fiber diffraction.Polyanion-induced self-association of complement factor H.A novel targeted inhibitor of the alternative pathway of complement and its therapeutic application in ischemia/reperfusion injury.Constrained solution scattering modelling of human antibodies and complement proteins reveals novel biological insights.Use of time-resolved FRET to validate crystal structure of complement regulatory complex between C3b and factor H (N terminus).Complement factor H binds at two independent sites to C-reactive protein in acute phase concentrations.Association of CFH and SERPING1 polymorphisms with anterior uveitis.Two distinct conformations of factor H regulate discrete complement-binding functions in the fluid phase and at cell surfaces
P2860
Q21134757-E335F75C-C366-4E83-BE80-BE5D037C8F57Q24604385-1178FE8F-2CBC-4D64-AF83-EBB034F735FFQ24646284-1804933B-537A-43D7-9A1B-D23B6EF3B0AAQ24646723-5C6D24A8-EBB4-4130-87BD-B488D7FD6C19Q27673696-4BAF9521-AB7E-4522-BB92-65CF4266CA94Q28542387-C15004FB-8153-4C7C-B574-52A2DF34C1E1Q28565182-AA986649-BFCE-48B8-9B54-81D50703D849Q30377280-BF7A3BB8-F9C1-4C8E-B8AA-FA392C3927C2Q30974944-879EC3E5-C274-4CA4-B2D7-3DCE5C42ACFCQ33382097-1D31F64D-6413-49E0-A8C9-1BBE32367314Q34067107-088B3E45-BD7C-4DDD-842C-55F41AD64AB9Q34376170-A0FAFE4B-7439-457C-B46F-DFEAE2BB586FQ34976109-E8958339-B03A-4611-AED3-C2F2098CB59FQ35002974-4DE52072-59CC-40A1-B7C1-42057E779C9DQ35547043-6C198695-9345-428E-9CF2-291DAAEDEF36Q36182912-E1D26242-8644-482D-B83C-3D7666997673Q36967403-F92CB23A-3A68-4B30-9E97-3EA3CAFE6847Q37137976-F4D37E71-A9FA-4439-A22F-08FC5986BB91Q37181643-01C09C10-B0F4-40FD-BF9A-3371DADE5350Q37434667-EE0594C2-CE44-4D0D-8330-6B65391F4B43Q39757500-42C24742-0E46-441C-9F3D-683E8E53E85AQ41837619-F00F396F-5350-465D-A556-4820AF784122Q42021566-FC4E90E4-7EA4-4376-8CBC-3F5C98AD4B25Q45280992-D84C36B8-5542-4272-BCE1-CB7EF295FB91Q58738012-7C846367-FED3-499F-850C-C02E1835436A
P2860
The regulatory SCR-1/5 and cell surface-binding SCR-16/20 fragments of factor H reveal partially folded-back solution structures and different self-associative properties
description
2008 nî lūn-bûn
@nan
2008 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
The regulatory SCR-1/5 and cel ...... nt self-associative properties
@ast
The regulatory SCR-1/5 and cel ...... nt self-associative properties
@en
The regulatory SCR-1/5 and cel ...... nt self-associative properties
@nl
type
label
The regulatory SCR-1/5 and cel ...... nt self-associative properties
@ast
The regulatory SCR-1/5 and cel ...... nt self-associative properties
@en
The regulatory SCR-1/5 and cel ...... nt self-associative properties
@nl
prefLabel
The regulatory SCR-1/5 and cel ...... nt self-associative properties
@ast
The regulatory SCR-1/5 and cel ...... nt self-associative properties
@en
The regulatory SCR-1/5 and cel ...... nt self-associative properties
@nl
P2093
P3181
P1476
The regulatory SCR-1/5 and cel ...... nt self-associative properties
@en
P2093
Azubuike I Okemefuna
Hannah E Gilbert
Kim M Griggs
Rebecca J Ormsby
Stephen J Perkins
P304
P3181
P356
10.1016/J.JMB.2007.09.026
P407
P577
2007-09-14T00:00:00Z