Active site of mycobacterial dUTPase: structural characteristics and a built-in sensor
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The metagenomic telescopeKeeping uracil out of DNA: physiological role, structure and catalytic mechanism of dUTPasesThe Flexible Motif V of Epstein-Barr Virus Deoxyuridine 5'-Triphosphate Pyrophosphatase Is Essential for CatalysisMolecular shape and prominent role of beta-strand swapping in organization of dUTPase oligomersCrystallization and crystal-packing studies ofChlorellavirus deoxyuridine triphosphataseDirect contacts between conserved motifs of different subunits provide major contribution to active site organization in human and mycobacterial dUTPasesAromatic stacking between nucleobase and enzyme promotes phosphate ester hydrolysis in dUTPaseTying down the arm in Bacillus dUTPase: structure and mechanismStructure and enzymatic mechanism of a moonlighting dUTPaseNLS copy-number variation governs efficiency of nuclear import--case study on dUTPasesThe dUTPase enzyme is essential in Mycobacterium smegmatisCatalytic mechanism of α-phosphate attack in dUTPase is revealed by X-ray crystallographic snapshots of distinct intermediates, 31P-NMR spectroscopy and reaction path modelling.Calpain-catalyzed proteolysis of human dUTPase specifically removes the nuclear localization signal peptide.Differential control of dNTP biosynthesis and genome integrity maintenance by the dUTPase superfamily enzymes.Nucleotide pyrophosphatase employs a P-loop-like motif to enhance catalytic power and NDP/NTP discrimination.Evidence-Based Structural Model of the Staphylococcal Repressor Protein: Separation of Functions into Different Domains.Preventive DNA repair by sanitizing the cellular (deoxy)nucleoside triphosphate pool.Crystallization and preliminary crystallographic analysis of dUTPase from the φ11 helper phage of Staphylococcus aureus.A Hidden Active Site in the Potential Drug Target Mycobacterium tuberculosis dUTPase Is Accessible through Small Amplitude Protein Conformational Changes.Cellular response to efficient dUTPase RNAi silencing in stable HeLa cell lines perturbs expression levels of genes involved in thymidylate metabolism.Drosophila proteins involved in metabolism of uracil-DNA possess different types of nuclear localization signals.Trading in cooperativity for specificity to maintain uracil-free DNA.Expanding the DNA alphabet in the fruit fly: uracil enrichment in genomic DNA.Moonlighting bacteriophage proteins derepress staphylococcal pathogenicity islands.Highly potent dUTPase inhibition by a bacterial repressor protein reveals a novel mechanism for gene expression control.Mobility and temperature resistance of trehalose mycolates as key characteristics of the outer membrane of Mycobacterium tuberculosis.The dUTPase of white spot syndrome virus assembles its active sites in a noncanonical manner.Is there a sphingomyelin-based hydrogen bond barrier at the mammalian host-schistosome parasite interface?dUTPase expression correlates with cell division potential in Drosophila melanogaster.The Stl repressor from Staphylococcus aureus is an efficient inhibitor of the eukaryotic fruitfly dUTPase.Evolutionary and mechanistic insights into substrate and product accommodation of CTP:phosphocholine cytidylyltransferase from Plasmodium falciparum.Potential steps in the evolution of a fused trimeric all-β dUTPase involve a catalytically competent fused dimeric intermediate.
P2860
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P2860
Active site of mycobacterial dUTPase: structural characteristics and a built-in sensor
description
2008 nî lūn-bûn
@nan
2008 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Active site of mycobacterial dUTPase: structural characteristics and a built-in sensor
@ast
Active site of mycobacterial dUTPase: structural characteristics and a built-in sensor
@en
Active site of mycobacterial dUTPase: structural characteristics and a built-in sensor
@nl
type
label
Active site of mycobacterial dUTPase: structural characteristics and a built-in sensor
@ast
Active site of mycobacterial dUTPase: structural characteristics and a built-in sensor
@en
Active site of mycobacterial dUTPase: structural characteristics and a built-in sensor
@nl
prefLabel
Active site of mycobacterial dUTPase: structural characteristics and a built-in sensor
@ast
Active site of mycobacterial dUTPase: structural characteristics and a built-in sensor
@en
Active site of mycobacterial dUTPase: structural characteristics and a built-in sensor
@nl
P2093
P3181
P1476
Active site of mycobacterial dUTPase: structural characteristics and a built-in sensor
@en
P2093
Balázs Varga
Beáta G Vértessy
Eniko Takács
Nikolett Nagy
Péter Nagy
P3181
P356
10.1016/J.BBRC.2008.05.130
P407
P577
2008-06-02T00:00:00Z