Host Determinant Residue Lysine 627 Lies on the Surface of a Discrete, Folded Domain of Influenza Virus Polymerase PB2 Subunit
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Library methods for structural biology of challenging proteins and their complexesNovel Polymerase Gene Mutations for Human Adaptation in Clinical Isolates of Avian H5N1 Influenza VirusesThe structure of a biologically active influenza virus ribonucleoprotein complexStructural Basis of the Influenza A Virus RNA Polymerase PB2 RNA-binding Domain Containing the Pathogenicity-determinant Lysine 627 ResidueThe cap-snatching endonuclease of influenza virus polymerase resides in the PA subunitStructural insight into the essential PB1–PB2 subunit contact of the influenza virus RNA polymeraseBiological and Structural Characterization of a Host-Adapting Amino Acid in Influenza VirusStructural and Biochemical Basis for Development of Influenza Virus Inhibitors Targeting the PA EndonucleaseThe Protein Maker: an automated system for high-throughput parallel purificationOrganization of the influenza virus replication machineryConformational polymorphism of m7GTP in crystal structure of the PB2 middle domain from human influenza A virusCrystallization and preliminary X-ray diffraction studies of a surface mutant of the middle domain of PB2 from human influenza A (H1N1) virusComparative structural and functional analysis of orthomyxovirus polymerase cap-snatching domainsInvestigating the Role of Large-Scale Domain Dynamics in Protein-Protein InteractionsGeneration and comprehensive analysis of an influenza virus polymerase cellular interaction networkEmergence and pandemic potential of swine-origin H1N1 influenza virusConserved features of the PB2 627 domain impact influenza virus polymerase function and replicationPB2 mutations D701N and S714R promote adaptation of an influenza H5N1 virus to a mammalian hostSurvival analysis of infected mice reveals pathogenic variations in the genome of avian H1N1 virusesPhylogenetic Analysis and Functional Characterization of the Influenza A H5N1 PB2 Gene.Adaptive strategies of the influenza virus polymerase for replication in humansComplete-proteome mapping of human influenza A adaptive mutations: implications for human transmissibility of zoonotic strains.PB2 residue 271 plays a key role in enhanced polymerase activity of influenza A viruses in mammalian host cells.Structures of influenza A proteins and insights into antiviral drug targets.PB2 residue 158 is a pathogenic determinant of pandemic H1N1 and H5 influenza a viruses in mice.Charting the host adaptation of influenza viruses.Genetic and antigenic characterization of H1 influenza viruses from United States swine from 2008.Nationwide molecular surveillance of pandemic H1N1 influenza A virus genomes: Canada, 2009.PA residues in the 2009 H1N1 pandemic influenza virus enhance avian influenza virus polymerase activity in mammalian cells.Gene Composer in a structural genomics environmentThe RNA polymerase PB2 subunit of influenza A/HongKong/156/1997 (H5N1) restricts the replication of reassortant ribonucleoprotein complexes [corrected]Adaptation of avian influenza A virus polymerase in mammals to overcome the host species barrierAdapting global influenza management strategies to address emerging viruses.Influenza virus RNA polymerase: insights into the mechanisms of viral RNA synthesis.Expression of Helicobacter pylori CagA domains by library-based construct screening.Genetic trans-complementation establishes a new model for influenza virus RNA transcription and replication.Expression of soluble, active fragments of the morphogenetic protein SpoIIE from Bacillus subtilis using a library-based construct screen.CoESPRIT: a library-based construct screening method for identification and expression of soluble protein complexesA high-throughput immobilized bead screen for stable proteins and multi-protein complexes.Experimental mapping of soluble protein domains using a hierarchical approach
P2860
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P2860
Host Determinant Residue Lysine 627 Lies on the Surface of a Discrete, Folded Domain of Influenza Virus Polymerase PB2 Subunit
description
2008 nî lūn-bûn
@nan
2008 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Host Determinant Residue Lysin ...... a Virus Polymerase PB2 Subunit
@ast
Host Determinant Residue Lysin ...... a Virus Polymerase PB2 Subunit
@en
Host Determinant Residue Lysin ...... a Virus Polymerase PB2 Subunit
@nl
type
label
Host Determinant Residue Lysin ...... a Virus Polymerase PB2 Subunit
@ast
Host Determinant Residue Lysin ...... a Virus Polymerase PB2 Subunit
@en
Host Determinant Residue Lysin ...... a Virus Polymerase PB2 Subunit
@nl
prefLabel
Host Determinant Residue Lysin ...... a Virus Polymerase PB2 Subunit
@ast
Host Determinant Residue Lysin ...... a Virus Polymerase PB2 Subunit
@en
Host Determinant Residue Lysin ...... a Virus Polymerase PB2 Subunit
@nl
P2093
P2860
P50
P3181
P1433
P1476
Host Determinant Residue Lysin ...... a Virus Polymerase PB2 Subunit
@en
P2093
Delphine Guilligay
Franck Tarendeau
Rob W H Ruigrok
P2860
P304
P3181
P356
10.1371/JOURNAL.PPAT.1000136
P577
2008-08-29T00:00:00Z