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Library methods for structural biology of challenging proteins and their complexesStructure and nuclear import function of the C-terminal domain of influenza virus polymerase PB2 subunitThe structural basis for cap binding by influenza virus polymerase subunit PB2Host Determinant Residue Lysine 627 Lies on the Surface of a Discrete, Folded Domain of Influenza Virus Polymerase PB2 SubunitThe cap-snatching endonuclease of influenza virus polymerase resides in the PA subunitCooperative binding of two acetylation marks on a histone tail by a single bromodomainDevelopment of a Peptide that Selectively Activates Protein Phosphatase-1 in Living CellsStructure of the Phosphatase Domain of the Cell Fate Determinant SpoIIE from Bacillus subtilisStructural insight into cap-snatching and RNA synthesis by influenza polymeraseRecent advances in universal TA cloning methods for use in function studies.A new plasmid display technology for the in vitro selection of functional phenotype-genotype linked proteins.Combinatorial library approaches for improving soluble protein expression in Escherichia coli.Implementation of semi-automated cloning and prokaryotic expression screening: the impact of SPINE.Structural basis for the oligomerization of the MADS domain transcription factor SEPALLATA3 in Arabidopsis.Solubility survey of fragments of the neurofibromatosis type 1 protein neurofibromin.Expression of Helicobacter pylori CagA domains by library-based construct screening.ESPRIT: an automated, library-based method for mapping and soluble expression of protein domains from challenging targets.Expression of soluble, active fragments of the morphogenetic protein SpoIIE from Bacillus subtilis using a library-based construct screen.CoESPRIT: a library-based construct screening method for identification and expression of soluble protein complexesORF-selector ESPRIT: a second generation library screen for soluble protein expression employing precise open reading frame selection.Influenza A virus polymerase: structural insights into replication and host adaptation mechanismsInteraction of the influenza A virus polymerase PB2 C-terminal region with importin alpha isoforms provides insights into host adaptation and polymerase assembly.Molecular determinants for nuclear import of influenza A PB2 by importin α isoforms 3 and 7.Influenza Polymerase Can Adopt an Alternative Configuration Involving a Radical Repacking of PB2 Domains.Structural insights into the architecture of the Shigella flexneri virulence factor IcsA/VirG and motifs involved in polar distribution and secretion.Structural Characterization of the SMRT Corepressor Interacting with Histone Deacetylase 7.Death-Associated Protein Kinase Activity Is Regulated by Coupled Calcium/Calmodulin Binding to Two Distinct SitesTowards an atomic resolution understanding of the influenza virus replication machinery.Mouse Rif1 is a regulatory subunit of protein phosphatase 1 (PP1).Structural and biophysical characterization of murine rif1 C terminus reveals high specificity for DNA cruciform structures.Large-Scale Conformational Dynamics Control H5N1 Influenza Polymerase PB2 Binding to Importin α.Biological and biophysical properties of the histone deacetylase inhibitor suberoylanilide hydroxamic acid are affected by the presence of short alkyl groups on the phenyl ring.A structural organization for the Disrupted in Schizophrenia 1 protein, identified by high-throughput screening, reveals distinctly folded regions, which are bisected by mental illness-related mutations.Expression and Characterization of Levansucrase from Clostridium acetobutylicum.A universal mini-vector and an annealing of PCR products (APP)-based cloning strategy for convenient molecular biological manipulations.ESPRIT: A Method for Defining Soluble Expression Constructs in Poorly Understood Gene Sequences.Auxin sensing is a property of an unstructured domain in the Auxin Response Factor ETTIN of Arabidopsis thalianaFabrication of protein function microarrays for systems-oriented proteomic analysisThree Novel Escherichia coli Vectors for Convenient and Efficient Molecular Biological Manipulations
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Q27008422-D3C25CD1-8A74-4C23-81AF-D7316B73EFAFQ27643860-318CD9C5-342D-44CE-A6B8-CBAF11DF14E2Q27650520-A966E531-9CB1-4AAE-875B-E4B88245D227Q27651972-DAB0B95A-9CFA-4915-B5A6-1BF499289F93Q27653657-5B72CA8C-6473-4C9C-A184-C8C3D43B5BADQ27657619-43C0B36F-C681-4636-89C9-80AF364336C4Q27672858-E428D4F9-C3E8-4506-A6D0-2A5D84891BB8Q27675791-6D512317-4E63-445B-8C16-5FA1A31801F0Q27696194-1C1687FA-DE5D-44CB-979D-DB5FEEE5DC24Q30392430-19983B4C-C95A-40D2-9E3F-C2D6189A0BA2Q31014722-BC9B5EEC-3D8B-44D2-980A-A3D26B5E4E9BQ33230052-48E25AB5-6BF2-43A7-8FA0-14618D0AEA65Q33258379-C595C3E3-E063-4F51-BA55-6BE8454069BDQ33359110-12330B42-2156-4E11-88CF-2E6B414E3787Q33396139-B3ACBC34-DB5D-4DFB-8C73-E7A97321BBE0Q33399907-2CC325A4-4965-4489-9CAC-3949E726E96EQ33537565-27F0B670-8CAA-42A7-969F-A64404ECD8E5Q33684517-06C0C318-CB3A-4321-AC6C-E2D97D0F8958Q33834096-3F994022-D014-4F95-A2E3-825955E2FE71Q33880486-BCC61E37-D326-4C34-BF56-2E26C69BE112Q34121115-B96AAEB0-43F4-4669-9CEC-41FB4D60D260Q34695795-F4D48339-E56B-459F-993C-E9871DE3BC55Q35136748-F9070571-E5E8-458A-AE6A-B3D4E4F72F24Q35879897-4A2C2108-5F29-49B7-B892-A1C58C2A59FFQ36299663-71CB0BCD-4070-4987-845A-2A40D62E6893Q36407702-B4C3FAFC-DDF1-4EFB-9884-A0C6D54853CEQ37000278-D8C0D0A3-C624-4D49-863D-F2A532514FEDQ37671352-CCF09091-5B52-4760-809A-81C15A173B4CQ38775921-8836B9DF-D8CF-4CC1-9043-67BA354A9B6FQ39661785-ACAE9ACF-720A-4FA2-94D9-FFAFDBCDD381Q41281689-E507A2DF-D35C-48FC-99C6-50F63C0CB6D5Q43167383-C9D1EFC9-F4D3-4B46-B51B-FAA11191C456Q47788104-0A46F0C8-0F0F-4528-858E-1A7C54F423D7Q48364291-FAC556AA-1184-4EAC-9CA7-9CAFE41758DDQ49968342-8B6B7F8E-39BC-49E7-8DEF-D94FBB22C563Q51021243-94E9E5D8-015A-40B6-AEEB-E6D0D5A8B0A7Q57159197-336A3185-22A8-405D-A908-805BAD2E8A0EQ81620398-85B3C2EF-8042-4DCB-8904-97868C865613Q88808536-330578FA-885B-4D9B-87CC-304F677F965B
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description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Darren J Hart
@ast
Darren J Hart
@en
Darren J Hart
@es
Darren J Hart
@nl
Darren J Hart
@sl
type
label
Darren J Hart
@ast
Darren J Hart
@en
Darren J Hart
@es
Darren J Hart
@nl
Darren J Hart
@sl
prefLabel
Darren J Hart
@ast
Darren J Hart
@en
Darren J Hart
@es
Darren J Hart
@nl
Darren J Hart
@sl
P214
P106
P214
P31
P496
0000-0002-3502-2002
P734
P7859
viaf-207278847