Structural Evidence for Effectiveness of Darunavir and Two Related Antiviral Inhibitors against HIV-2 Protease
about
A highly intensified ART regimen induces long-term viral suppression and restriction of the viral reservoir in a simian AIDS modelCritical differences in HIV-1 and HIV-2 protease specificity for clinical inhibitorsSmall Molecule Regulation of Protein Conformation by Binding in the Flap of HIV ProteaseRevealing the dimer dissociation and existence of a folded monomer of the mature HIV-2 proteaseRevealing origin of decrease in potency of darunavir and amprenavir against HIV-2 relative to HIV-1 protease by molecular dynamics simulations.Synthesis and biological evaluation of novel allophenylnorstatine-based HIV-1 protease inhibitors incorporating high affinity P2-ligands.HIV-1 Protease: Structural Perspectives on Drug ResistanceModulation of human immunodeficiency virus type 1 protease autoprocessing by charge properties of surface residue 69.Role of darunavir in the management of HIV infection.How does curcumin work with poor bioavailability? Clues from experimental and theoretical studies.Four Amino Acid Changes in HIV-2 Protease Confer Class-Wide Sensitivity to Protease Inhibitors.A Direct Interaction with RNA Dramatically Enhances the Catalytic Activity of the HIV-1 Protease In VitroAnalysis of the HIV-2 protease's adaptation to various ligands: characterization of backbone asymmetry using a structural alphabet.Exploration of the effect of sequence variations located inside the binding pocket of HIV-1 and HIV-2 proteases.Exploring the Reasons for Decrease in Binding Affinity of HIV-2 Against HIV-1 Protease Complex Using Interaction Entropy Under Polarized Force Field
P2860
Q27344720-7AF8618B-9719-4326-BE78-7816014855F8Q27676688-11602A3C-1966-4C9D-B99D-EE3CB0EA5B7EQ27677124-0C21FE45-DD08-484C-9E4A-FDF9BAEF949DQ33650307-CD5B1A82-D7F3-4919-9309-CB4A9F765605Q34440391-410C99F9-2D4A-44AE-AEEF-88311A0DC22CQ35231732-1B1BA5AD-1D45-43DC-8175-B013F43FDB08Q35259855-C769C94F-82F9-4C22-B1D9-FFC34C2315D4Q37256706-4DF9DFB7-3795-4F35-88F0-3AE4362BECE5Q37957871-929DA858-34CD-4ADB-A154-8E180C9ECE15Q38541625-97A8D9CC-BCE2-4D6C-AB7D-0FF659B2C852Q38820118-CBCBF6BB-3390-41F2-8879-C35994655ED2Q41730903-D100F136-98E9-4D47-B514-E320107037D3Q48240350-C09215B5-10A1-471D-B75D-58E80F00F4A5Q52595330-763F7F0A-AF4E-4261-B072-D90BC73DB22CQ57167603-A618C661-3B26-4EDF-AA0D-A54881BF58A6
P2860
Structural Evidence for Effectiveness of Darunavir and Two Related Antiviral Inhibitors against HIV-2 Protease
description
2008 nî lūn-bûn
@nan
2008 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Structural Evidence for Effect ...... ibitors against HIV-2 Protease
@ast
Structural Evidence for Effect ...... ibitors against HIV-2 Protease
@en
Structural Evidence for Effect ...... ibitors against HIV-2 Protease
@nl
type
label
Structural Evidence for Effect ...... ibitors against HIV-2 Protease
@ast
Structural Evidence for Effect ...... ibitors against HIV-2 Protease
@en
Structural Evidence for Effect ...... ibitors against HIV-2 Protease
@nl
prefLabel
Structural Evidence for Effect ...... ibitors against HIV-2 Protease
@ast
Structural Evidence for Effect ...... ibitors against HIV-2 Protease
@en
Structural Evidence for Effect ...... ibitors against HIV-2 Protease
@nl
P2093
P2860
P1476
Structural Evidence for Effect ...... ibitors against HIV-2 Protease
@en
P2093
Andrey Y Kovalevsky
Annie Aniana
Arun K Ghosh
Irene T Weber
John M Louis
P2860
P304
P356
10.1016/J.JMB.2008.09.031
P407
P577
2008-12-05T00:00:00Z