The structure of the efflux pump AcrB in complex with bile acid
about
Efflux-mediated drug resistance in bacteria: an updateRecent Advances in Multi-Drug Resistance (MDR) Efflux Pump Inhibitors of Gram-Positive Bacteria S. aureusFunctional rotation of the transporter AcrB: insights into drug extrusion from simulationsStructures of the multidrug exporter AcrB reveal a proximal multisite drug-binding pocketTransport of drugs by the multidrug transporter AcrB involves an access and a deep binding pocket that are separated by a switch-loopStructural basis of RND-type multidrug exportersAcrB trimer stability and efflux activity, insight from mutagenesis studiesFunctional relevance of AcrB Trimerization in pump assembly and substrate bindingAcrA suppressor alterations reverse the drug hypersensitivity phenotype of a TolC mutant by inducing TolC aperture opening.Structure and mechanism of RND-type multidrug efflux pumpsRole of the HefC efflux pump in Helicobacter pylori cholesterol-dependent resistance to ceragenins and bile saltsEfflux pumps of the resistance-nodulation-division family: a perspective of their structure, function, and regulation in gram-negative bacteria.The challenge of efflux-mediated antibiotic resistance in Gram-negative bacteria.Stepwise substrate translocation mechanism revealed by free energy calculations of doxorubicin in the multidrug transporter AcrB.Assembly and transport mechanism of tripartite drug efflux systems.Structural and functional aspects of the multidrug efflux pump AcrB.Some ligands enhance the efflux of other ligands by the Escherichia coli multidrug pump AcrB.Strategies for bypassing the membrane barrier in multidrug resistant Gram-negative bacteria.Broad-specificity efflux pumps and their role in multidrug resistance of Gram-negative bacteria.An overview of bacterial efflux pumps and computational approaches to study efflux pump inhibitors.Transport of lipophilic carboxylates is mediated by transmembrane helix 2 in multidrug transporter AcrB.Substrate path in the AcrB multidrug efflux pump of Escherichia coli.The Diamond Light Source and the challenges ahead for structural biology: some informal remarks.Dissecting the function of a protruding loop in AcrB trimerization.Assembling of AcrB trimer in cell membrane.Crystallographic Analysis of Drug and Inhibitor-Binding Structure of RND-Type Multidrug Exporter AcrB in Physiologically Relevant Asymmetric Crystals.Accumulation and efflux of polychlorinated biphenyls in Escherichia coli.
P2860
Q24609407-DDD46FDF-BE79-4BD0-A423-EE7C36CB90DEQ26829852-E7770E02-692E-4470-9169-052517B51A92Q27334906-C6EF2280-62E1-4067-BC7E-46D1E1F88932Q27675850-C20A9935-5521-4B48-8A58-85B2A8F2435FQ27678230-6008469B-F2C2-451F-A372-6278E5765799Q28085595-CD6C5D8D-5894-4E4C-8E13-DFFDCE39368EQ28478270-5EC1C092-B4B5-46B6-9A6A-9E1C6275BF36Q28539846-0D294A75-479E-4FA5-B786-98FAAC1DD00AQ33871411-25F196F1-56E9-498E-8D00-93D753A10347Q34194314-B538AB79-E4B6-43E1-B95E-D91523A3DC15Q34484733-842F966A-00B6-4D6C-B380-22098F37B190Q35329956-B44E53A5-A0B1-421D-9DE3-3D0F8D2B73CFQ35482558-C9B2996F-3B25-4574-ADDB-33AD35D1CB84Q36129573-1931163C-21B1-47F9-9A2C-88F8FAD8E56FQ37165073-D72509C5-05CA-4C08-9458-0028C5F31C6EQ37488259-0DB183FE-3B72-4794-B6CB-34D5DBBE7FE3Q37632922-614EFD5B-01D6-43A6-9CAA-A41DDE2E75E3Q37872942-1EFA56E6-754D-421E-A7B4-F0E3BCCC6456Q37894832-A6107E7E-8BEC-4299-B6E7-A244160408E8Q38715925-C9C35631-130F-450A-A606-E93765EF2E87Q39498459-814A4EB5-C7EB-451B-BCAA-44769E5AA5F8Q41406243-2A6713AD-6E0B-49A5-B2D2-2C147B2BD577Q42069819-11B3A82D-DA3B-4F39-8790-EF13F2DE7C25Q46020138-70DD5B31-7F39-47E3-9B8A-9E250B34E861Q47100600-2A14A948-FB2C-48F7-92D5-133E6B6BB322Q49607006-3A50BE48-F38E-45B0-BE89-0A470C7FED65Q54342035-3214BDE6-E346-4C35-8496-B29DB008F7E0
P2860
The structure of the efflux pump AcrB in complex with bile acid
description
2008 nî lūn-bûn
@nan
2008 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
The structure of the efflux pump AcrB in complex with bile acid
@ast
The structure of the efflux pump AcrB in complex with bile acid
@en
The structure of the efflux pump AcrB in complex with bile acid
@nl
type
label
The structure of the efflux pump AcrB in complex with bile acid
@ast
The structure of the efflux pump AcrB in complex with bile acid
@en
The structure of the efflux pump AcrB in complex with bile acid
@nl
prefLabel
The structure of the efflux pump AcrB in complex with bile acid
@ast
The structure of the efflux pump AcrB in complex with bile acid
@en
The structure of the efflux pump AcrB in complex with bile acid
@nl
P2093
P2860
P50
P1476
The structure of the efflux pump AcrB in complex with bile acid
@en
P2093
Jan-Willem De Gier
Mirjam M Klepsch
Ralf Flaig
P2860
P304
P356
10.1080/09687680802552257
P577
2008-12-01T00:00:00Z