Crystal Structures of Cytochrome P450 105P1 from Streptomyces avermitilis: Conformational Flexibility and Histidine Ligation State
about
Pentalenic acid is a shunt metabolite in the biosynthesis of the pentalenolactone family of metabolites: hydroxylation of 1-deoxypentalenic acid mediated by CYP105D7 (SAV_7469) of Streptomyces avermitilisP450cam Visits an Open Conformation in the Absence of Substrate ,Regio- and stereospecificity of filipin hydroxylation sites revealed by crystal structures of cytochrome P450 105P1 and 105D6 from Streptomyces avermitilis.Crystal structure of a phenol-coupling P450 monooxygenase involved in teicoplanin biosynthesisDouble electron-electron resonance shows cytochrome P450cam undergoes a conformational change in solution upon binding substrateNovel Aromatase Inhibitors by Structure-Guided DesignSubstrate Recognition by the Multifunctional Cytochrome P450 MycG in Mycinamicin Hydroxylation and Epoxidation ReactionsStructural basis for the 4'-hydroxylation of diclofenac by a microbial cytochrome P450 monooxygenaseCytochrome P450 OxyBtei catalyzes the first phenolic coupling step in teicoplanin biosynthesisStructure of OxyA tei: completing our picture of the glycopeptide antibiotic producing Cytochrome P450 cascadeMore than just recruitment: the X-domain influences catalysis of the first phenolic coupling reaction in A47934 biosynthesis by Cytochrome P450 StaHBiochemical and structural characterisation of the second oxidative crosslinking step during the biosynthesis of the glycopeptide antibiotic A47934Three clusters of conformational states in p450cam reveal a multistep pathway for closing of the substrate access channel.In-silico and In-vitro based studies of Streptomyces peucetius CYP107N3 for oleic acid epoxidation.Intramolecular heme ligation of the cytochrome P450 2C9 R108H mutant demonstrates pronounced conformational flexibility of the B-C loop region: implications for substrate binding.CYP105-diverse structures, functions and roles in an intriguing family of enzymes in Streptomyces.Structural Analysis of the Streptomyces avermitilis CYP107W1-Oligomycin A Complex and Role of the Tryptophan 178 Residue.A role for hydrophobicity in a Diels-Alder reaction catalyzed by pyridyl-modified RNA.Conformational plasticity and structure/function relationships in cytochromes P450.Diversity of P450 enzymes in the biosynthesis of natural productsGenome mining of the Streptomyces avermitilis genome and development of genome-minimized hosts for heterologous expression of biosynthetic gene clusters.Cytochromes P450 for natural product biosynthesis in Streptomyces: sequence, structure, and function.Peptide δ-Turn: Literature Survey and Recent Progress.Crystal Structure of Cytochrome P450 (CYP105P2) from Streptomyces peucetius and Its Conformational Changes in Response to Substrate Binding.The conformation of P450cam in complex with putidaredoxin is dependent on oxidation state.Substrate Recognition by a Dual-Function P450 Monooxygenase GfsF Involved in FD-891 Biosynthesis.Characterization of a novel cytochrome P450 from Amycolatopsis sp. CGMCC1149 for hydroxylation of lovastatin.
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P2860
Crystal Structures of Cytochrome P450 105P1 from Streptomyces avermitilis: Conformational Flexibility and Histidine Ligation State
description
2009 nî lūn-bûn
@nan
2009 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Crystal Structures of Cytochro ...... y and Histidine Ligation State
@ast
Crystal Structures of Cytochro ...... y and Histidine Ligation State
@en
Crystal Structures of Cytochro ...... y and Histidine Ligation State
@nl
type
label
Crystal Structures of Cytochro ...... y and Histidine Ligation State
@ast
Crystal Structures of Cytochro ...... y and Histidine Ligation State
@en
Crystal Structures of Cytochro ...... y and Histidine Ligation State
@nl
prefLabel
Crystal Structures of Cytochro ...... y and Histidine Ligation State
@ast
Crystal Structures of Cytochro ...... y and Histidine Ligation State
@en
Crystal Structures of Cytochro ...... y and Histidine Ligation State
@nl
P2093
P2860
P3181
P356
P1476
Crystal structures of cytochro ...... y and histidine ligation state
@en
P2093
Haruo Ikeda
Hirofumi Shoun
Lian-Hua Xu
Takayoshi Wakagi
P2860
P304
P3181
P356
10.1128/JB.01276-08
P407
P577
2008-12-12T00:00:00Z