Generation of single-chain LAGLIDADG homing endonucleases from native homodimeric precursor proteins
about
Efficient targeting of a SCID gene by an engineered single-chain homing endonucleaseHoming endonucleases: DNA scissors on a missionComputational reprogramming of homing endonuclease specificity at multiple adjacent base pairsMolecular basis of engineered meganuclease targeting of the endogenous human RAG1 locusExpanding LAGLIDADG endonuclease scaffold diversity by rapidly surveying evolutionary sequence spaceLAHEDES: the LAGLIDADG homing endonuclease database and engineering serverMolecular scissors under light control.DNA nicks promote efficient and safe targeted gene correction.A synthetic homing endonuclease-based gene drive system in the human malaria mosquitoComprehensive computational design of mCreI homing endonuclease cleavage specificity for genome engineering.A single-chain TALEN architecture for genome engineering.Meganucleases and other tools for targeted genome engineering: perspectives and challenges for gene therapy.Comprehensive homing endonuclease target site specificity profiling reveals evolutionary constraints and enables genome engineering applications.Engineering domain fusion chimeras from I-OnuI family LAGLIDADG homing endonucleases.The Structural Basis of Asymmetry in DNA Binding and Cleavage as Exhibited by the I-SmaMI LAGLIDADG Meganuclease.Targeted approaches for gene therapy and the emergence of engineered meganucleases.Artificial DNA cutters for DNA manipulation and genome engineering.Towards artificial metallonucleases for gene therapy: recent advances and new perspectives.Molecular scissors for in situ cellular repair.Recent advances in targeted genome engineering in mammalian systems.Chemical and biological approaches to improve the efficiency of homologous recombination in human cells mediated by artificial restriction DNA cutter.Homing endonucleases from mobile group I introns: discovery to genome engineering.Engineering altered protein-DNA recognition specificity.
P2860
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P2860
Generation of single-chain LAGLIDADG homing endonucleases from native homodimeric precursor proteins
description
2009 nî lūn-bûn
@nan
2009 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Generation of single-chain LAG ...... homodimeric precursor proteins
@ast
Generation of single-chain LAG ...... homodimeric precursor proteins
@en
Generation of single-chain LAG ...... homodimeric precursor proteins
@nl
type
label
Generation of single-chain LAG ...... homodimeric precursor proteins
@ast
Generation of single-chain LAG ...... homodimeric precursor proteins
@en
Generation of single-chain LAG ...... homodimeric precursor proteins
@nl
prefLabel
Generation of single-chain LAG ...... homodimeric precursor proteins
@ast
Generation of single-chain LAG ...... homodimeric precursor proteins
@en
Generation of single-chain LAG ...... homodimeric precursor proteins
@nl
P2093
P2860
P356
P1476
Generation of single-chain LAG ...... homodimeric precursor proteins
@en
P2093
Barry L Stoddard
Raymond J Monnat
Stefan Pellenz
P2860
P304
P356
10.1093/NAR/GKP004
P407
P577
2009-01-19T00:00:00Z