Inhibition of Wnt signaling by Dishevelled PDZ peptides - Wikidata - awgldk - TriplyDB

Inhibition of Wnt signaling by Dishevelled PDZ peptides

Inhibition of Wnt signaling by Dishevelled PDZ peptides

http://www.wikidata.org/entity/Q27653983

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Myristoylated Naked2 antagonizes Wnt-beta-catenin activity by degrading Dishevelled-1 at the plasma membrane KIF14 negatively regulates Rap1a-Radil signaling during breast cancer progression The development and application of a quantitative peptide microarray based approach to protein interaction domain specificity space Wnt/beta-catenin signaling and small molecule inhibitors MUSI: an integrated system for identifying multiple specificity from very large peptide or nucleic acid data sets PDZ domains and their binding partners: structure, specificity, and modification Wnt/beta-catenin signaling: components, mechanisms, and diseases Flavonoids and Wnt/β-catenin signaling: potential role in colorectal cancer therapies Elucidation of the binding preferences of peptide recognition modules: SH3 and PDZ domains PDZ Domain Recognition: Insight from Human Tax-Interacting Protein 1 (TIP-1) Interaction with Target Proteins Sulindac Inhibits Canonical Wnt Signaling by Blocking the PDZ Domain of the Protein Dishevelled Unusual binding interactions in PDZ domain crystal structures help explain binding mechanisms Structural Analysis of the Interaction between Dishevelled2 and Clathrin AP-2 Adaptor, A Critical Step in Noncanonical Wnt Signaling Identification of a Small Peptide That Inhibits PCSK9 Protein Binding to the Low Density Lipoprotein Receptor Allosteric peptides bind a caspase zymogen and mediate caspase tetramerization Periaxin and AHNAK Nucleoprotein 2 Form Intertwined Homodimers through Domain Swapping Identification of transmembrane protein 88 (TMEM88) as a dishevelled-binding protein Non-Canonical Wnt Predominates in Activated Rat Hepatic Stellate Cells, Influencing HSC Survival and Paracrine Stimulation of Kupffer Cells The role of flexibility and conformational selection in the binding promiscuity of PDZ domains Wnt isoform-specific interactions with coreceptor specify inhibition or potentiation of signaling by LRP6 antibodies A potent and selective small molecule inhibitor of sirtuin 1 promotes differentiation of pluripotent P19 cells into functional neurons Discovery of novel interacting partners of PSMD9, a proteasomal chaperone: Role of an Atypical and versatile PDZ-domain motif interaction and identification of putative functional modules Phosphorylation of Dishevelled by protein kinase RIPK4 regulates Wnt signaling.Cholesterol selectively activates canonical Wnt signalling over non-canonical Wnt signalling.Chemically modified peptide scaffolds target the CFTR-associated ligand PDZ domain Synthesis of potent dishevelled PDZ domain inhibitors guided by virtual screening and NMR studies Protein binding specificity versus promiscuity.Specificity and promiscuity in human glutaminase interacting protein recognition: insight from the binding of the internal and C-terminal motif.Mitotic inhibition of GRASP65 organelle tethering involves Polo-like kinase 1 (PLK1) phosphorylation proximate to an internal PDZ ligand Predicting PDZ domain mediated protein interactions from structure Small molecule modulators of Wnt/β-catenin signaling.Crystallization and preliminary diffraction analysis of the CAL PDZ domain in complex with a selective peptide inhibitor Characterization of diverse internal binding specificities of PDZ domains by yeast two-hybrid screening of a special peptide library HSP105 recruits protein phosphatase 2A to dephosphorylate β-catenin.Interaction analysis through proteomic phage display.Dishevelled binds the Discs large 'Hook' domain to activate GukHolder-dependent spindle positioning in Drosophila.Wnt/β-catenin signaling requires interaction of the Dishevelled DEP domain and C terminus with a discontinuous motif in Frizzled Rational design of DKK3 structure-based small peptides as antagonists of Wnt signaling pathway and in silico evaluation of their efficiency A novel cell-penetrating peptide suppresses breast tumorigenesis by inhibiting β-catenin/LEF-1 signaling.Targeting Wnt pathways in disease.

P2860

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P2860

Inhibition of Wnt signaling by Dishevelled PDZ peptides

http://www.wikidata.org/entity/Q27653983

description

2009 nî lūn-bûn

@nan

2009 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

2009年の論文

@ja

2009年論文

@yue

2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

@wuu

name

Inhibition of Wnt signaling by Dishevelled PDZ peptides

@ast

Inhibition of Wnt signaling by Dishevelled PDZ peptides

@en

Inhibition of Wnt signaling by Dishevelled PDZ peptides

@nl

type

label

Inhibition of Wnt signaling by Dishevelled PDZ peptides

@ast

Inhibition of Wnt signaling by Dishevelled PDZ peptides

@en

Inhibition of Wnt signaling by Dishevelled PDZ peptides

@nl

prefLabel

Inhibition of Wnt signaling by Dishevelled PDZ peptides

@ast

Inhibition of Wnt signaling by Dishevelled PDZ peptides

@en

Inhibition of Wnt signaling by Dishevelled PDZ peptides

@nl

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Nature Chemical Biology

P1476

Inhibition of Wnt signaling by Dishevelled PDZ peptides

@en

P2093

Mike Costa

http://www.w3.org/2001/XMLSchema#string

Rami N Hannoush

http://www.w3.org/2001/XMLSchema#string

Sachdev S Sidhu

http://www.w3.org/2001/XMLSchema#string

Ted Lau

http://www.w3.org/2001/XMLSchema#string

Yingnan Zhang

http://www.w3.org/2001/XMLSchema#string

P2888

P304

217-219

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scholarly article

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3211596

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10.1038/NCHEMBIO.152

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4

http://www.w3.org/2001/XMLSchema#string

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5

http://www.w3.org/2001/XMLSchema#string

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Brent A Appleton

Christian Wiesmann

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2009-03-01T00:00:00Z

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24147028

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1045457133

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19252499

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