N-(Pyridin-2-yl) arylsulfonamide inhibitors of 11beta-hydroxysteroid dehydrogenase type 1: Discovery of PF-915275

N-(Pyridin-2-yl) arylsulfonamide inhibitors of 11beta-hydroxysteroid dehydrogenase type 1: Discovery of PF-915275

Item
http://www.wikidata.org/entity/Q27655633
Optimization of 1,2,4-Triazolopyridines as Inhibitors of Human 11β-Hydroxysteroid Dehydrogenase Type 1 (11β-HSD-1)11β-Hydroxysteroid dehydrogenase type 1: relevance of its modulation in the pathophysiology of obesity, the metabolic syndrome and type 2 diabetes mellitus.Human hydroxysteroid dehydrogenases and pre-receptor regulation: insights into inhibitor design and evaluation.Crystal structures of 11β-hydroxysteroid dehydrogenase type 1 and their use in drug discovery.Practical approaches to resolving reactive metabolite liabilities in early discovery.Modulation of 11beta-hydroxysteroid dehydrogenase type 1 activity by 1,5-substituted 1H-tetrazolesReaction phenotyping to assess victim drug-drug interaction risks.First Selective CYP11B1 Inhibitors for the Treatment of Cortisol-Dependent DiseasesPharmacokinetic characterization of 2-(3-benzoyl)-4-hydroxy-1,1-dioxo-2H-1,2-benzothiazine-2-yl-1-phenylethanone, a novel 11β-hydroxysteroid dehydrogenase type 1 inhibitor in rats.
P2860

N-(Pyridin-2-yl) arylsulfonamide inhibitors of 11beta-hydroxysteroid dehydrogenase type 1: Discovery of PF-915275

Item
http://www.wikidata.org/entity/Q27655633
description
2009 nî lūn-bûn
@nan
2009 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
N-(Pyridin-2-yl) arylsulfonami ...... type 1: Discovery of PF-915275
@ast
N-(Pyridin-2-yl) arylsulfonami ...... type 1: Discovery of PF-915275
@en
N-(Pyridin-2-yl) arylsulfonami ...... type 1: Discovery of PF-915275
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type
label
N-(Pyridin-2-yl) arylsulfonami ...... type 1: Discovery of PF-915275
@ast
N-(Pyridin-2-yl) arylsulfonami ...... type 1: Discovery of PF-915275
@en
N-(Pyridin-2-yl) arylsulfonami ...... type 1: Discovery of PF-915275
@nl
prefLabel
N-(Pyridin-2-yl) arylsulfonami ...... type 1: Discovery of PF-915275
@ast
N-(Pyridin-2-yl) arylsulfonami ...... type 1: Discovery of PF-915275
@en
N-(Pyridin-2-yl) arylsulfonami ...... type 1: Discovery of PF-915275
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N-(Pyridin-2-yl) arylsulfonami ...... type 1: Discovery of PF-915275
@en
P2093
P304
P31
P356
10.1016/J.BMCL.2009.05.011
P407
P433
P478
P577
P5875
P698