Adaptive Ligand Binding by the Purine Riboswitch in the Recognition of Guanine and Adenine Analogs - Wikidata - awgldk - TriplyDB

Adaptive Ligand Binding by the Purine Riboswitch in the Recognition of Guanine and Adenine Analogs

Adaptive Ligand Binding by the Purine Riboswitch in the Recognition of Guanine and Adenine Analogs

http://www.wikidata.org/entity/Q27655921

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Reengineering orthogonally selective riboswitches Recognition of the bacterial second messenger cyclic diguanylate by its cognate riboswitch Small molecules targeting viral RNA Discrimination between Closely Related Cellular Metabolites by the SAM-I Riboswitch Riboswitch structure: an internal residue mimicking the purine ligand Novel Ligands for a Purine Riboswitch Discovered by RNA-Ligand Docking Insights into the Regulatory Landscape of the Lysine Riboswitch Structural principles of nucleoside selectivity in a 2′-deoxyguanosine riboswitch Influence of ground-state structure and Mg2+ binding on folding kinetics of the guanine-sensing riboswitch aptamer domain Nucleotides Adjacent to the Ligand-Binding Pocket are Linked to Activity Tuning in the Purine Riboswitch Emerging applications of riboswitches - from antibacterial targets to molecular tools Structure and dynamics of the deoxyguanosine-sensing riboswitch studied by NMR-spectroscopy Predicting loop-helix tertiary structural contacts in RNA pseudoknots.Novel riboswitch-binding flavin analog that protects mice against Clostridium difficile infection without inhibiting cecal flora.Multivector fluorescence analysis of the xpt guanine riboswitch aptamer domain and the conformational role of guanine The purine riboswitch as a model system for exploring RNA biology and chemistry RNA approaches the B-form in stacked single strand dinucleotide contexts.Role of tautomerism in RNA biochemistry.Differential analogue binding by two classes of c-di-GMP riboswitches Watson-Crick-like pairs in CCUG repeats: evidence for tautomeric shifts or protonation.Two Divalent Metal Ions and Conformational Changes Play Roles in the Hammerhead Ribozyme Cleavage Reaction.Structure and mechanism of purine-binding riboswitches.Recognition of Watson-Crick base pairs: constraints and limits due to geometric selection and tautomerism.RNA triplexes: from structural principles to biological and biotech applications.Direct observation of multiple tautomers of oxythiamine and their recognition by the thiamine pyrophosphate riboswitch.Loop-loop interaction in an adenine-sensing riboswitch: a molecular dynamics study Mechanisms for differentiation between cognate and near-cognate ligands by purine riboswitches.Role of the adenine ligand on the stabilization of the secondary and tertiary interactions in the adenine riboswitch.The Emerging Role of RNA as a Therapeutic Target for Small Molecules.Cooperativity, allostery and synergism in ligand binding to riboswitches.Cobalamin riboswitches exhibit a broad range of ability to discriminate between methylcobalamin and adenosylcobalamin.Experimental approaches for measuring pKa's in RNA and DNA.Single-molecule chemical denaturation of riboswitches.Bioinformatic analysis of riboswitch structures uncovers variant classes with altered ligand specificity.Visualizing transient Watson-Crick-like mispairs in DNA and RNA duplexes.Metabolic profiling in Caenorhabditis elegans provides an unbiased approach to investigations of dosage dependent lead toxicity.RNA Structural Dynamics As Captured by Molecular Simulations: A Comprehensive Overview.Using Genome Sequence to Enable the Design of Medicines and Chemical Probes.Allosteric mechanism of the V. vulnificus adenine riboswitch resolved by four-dimensional chemical mapping.Blueprints for Biosensors: Design, Limitations, and Applications

P2860

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P2860

Adaptive Ligand Binding by the Purine Riboswitch in the Recognition of Guanine and Adenine Analogs

http://www.wikidata.org/entity/Q27655921

description

2009 nî lūn-bûn

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2009 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2009 թվականի հունիսին հրատարակված գիտական հոդված

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2009年の論文

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Adaptive Ligand Binding by the ...... of Guanine and Adenine Analogs

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Adaptive Ligand Binding by the ...... of Guanine and Adenine Analogs

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Adaptive Ligand Binding by the ...... of Guanine and Adenine Analogs

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J.STR.2009.04.009

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Adaptive Ligand Binding by the ...... of Guanine and Adenine Analogs

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Andrea L Edwards

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Francis E Reyes

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Sunny D Gilbert

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P2860

Halogen bonds in biological molecules

The fidelity of DNA synthesis by eukaryotic replicative and translesion synthesis polymerases

Crystal structure of the lysine riboswitch regulatory mRNA element

An mRNA structure in bacteria that controls gene expression by binding lysine

Guanine riboswitch variants from Mesoplasma florum selectively recognize 2'-deoxyguanosine

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

The structural basis for the mutagenicity of O6-methyl-guanine lesions

Mutational Analysis of the Purine Riboswitch Aptamer Domain †

Structural basis of thiamine pyrophosphate analogues binding to the eukaryotic riboswitch

Structural insights into amino acid binding and gene control by a lysine riboswitch

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5034464

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10.1016/J.STR.2009.04.009

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6

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17

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26289702

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19523903

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structural biology

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2721690

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