New protein fold revealed by a 2.3-A resolution crystal structure of nerve growth factor
about
IL-17s adopt a cystine knot fold: structure and activity of a novel cytokine, IL-17F, and implications for receptor bindingCrystal structure of human platelet-derived growth factor BBMembers of the DAN family are BMP antagonists that form highly stable noncovalent dimersA unique human gene that spans over 230 kb in the human chromosome 8p11-12 and codes multiple family proteins sharing RNA-binding motifsMolecular modelling of the Norrie disease protein predicts a cystine knot growth factor tertiary structureThe nerve of ovulation-inducing factor in semenNeurotrophins: roles in neuronal development and functionNeurotrophin-regulated signalling pathwaysFormation of cystine slipknots in dimeric proteinsThe structures of the neurotrophin 4 homodimer and the brain-derived neurotrophic factor/neurotrophin 4 heterodimer reveal a common Trk-binding siteDetermination of protein structures--a series of fortunate events.Biophysical characterization of refolded Drosophila Spätzle, a cystine knot protein, reveals distinct properties of three isoformsMolecular and Structural Insight into proNGF Engagement of p75NTR and SortilinCytokine Spatzle binds to the Drosophila immunoreceptor Toll with a neurotrophin-like specificity and couples receptor activationGeneration of a high-fidelity antibody against nerve growth factor using library scanning mutagenesis and validation with structures of the initial and optimized Fab-antigen complexesThree-dimensional structure of recombinant human osteogenic protein 1: structural paradigm for the transforming growth factor beta superfamilyCrystal structure of a coagulogen, the clotting protein from horseshoe crab: a structural homologue of nerve growth factorX-ray structure of glial cell-derived neurotrophic factor at 1.9 A resolution and implications for receptor bindingVascular endothelial growth factor: crystal structure and functional mapping of the kinase domain receptor binding siteBinding of neurotrophin-3 to p75LNGFR, TrkA, and TrkB mediated by a single functional epitope distinct from that recognized by trkCRole of the cystine-knot motif at the C-terminus of rat mucin protein Muc2 in dimer formation and secretionConformational plasticity of proNGFN-linked oligosaccharides play a role in disulphide-dependent dimerization of intestinal mucin Muc2Pfam: a comprehensive database of protein domain families based on seed alignmentsCrystallization of Spätzle, a cystine-knot protein involved in embryonic development and innate immunity in Drosophila melanogaster.Overview of protein structural and functional folds.Overview of protein folds in the immune system.Protein crystallography for aspiring crystallographers or how to avoid pitfalls and traps in macromolecular structure determination.Characterizations of diverse residue clusters in protein three-dimensional structures.Targeted disruption of the BDNF gene perturbs brain and sensory neuron development but not motor neuron development.Characterization of symmetric complexes of nerve growth factor and the ectodomain of the pan-neurotrophin receptor, p75NTRDetection of ATP-binding to growth factors.Preferential self-association of basic fibroblast growth factor is stabilized by heparin during receptor dimerization and activation.Three-tier regulation of cell number plasticity by neurotrophins and Tolls in Drosophila.Mechanisms of activation of receptor tyrosine kinases: monomers or dimers.Ligand-induced receptor dimerization may be critical for signal transduction by choriogonadotropin.An extended surface of binding to Trk tyrosine kinase receptors in NGF and BDNF allows the engineering of a multifunctional pan-neurotrophin.Structure and distribution of modules in extracellular proteins.Protein-protein interactions in receptor activation and intracellular signalling.Acetyl-L-carnitine physical-chemical, metabolic, and therapeutic properties: relevance for its mode of action in Alzheimer's disease and geriatric depression.
P2860
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P2860
New protein fold revealed by a 2.3-A resolution crystal structure of nerve growth factor
description
1991 nî lūn-bûn
@nan
1991 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1991 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
name
New protein fold revealed by a 2.3-A resolution crystal structure of nerve growth factor
@ast
New protein fold revealed by a 2.3-A resolution crystal structure of nerve growth factor
@en
New protein fold revealed by a 2.3-A resolution crystal structure of nerve growth factor
@nl
type
label
New protein fold revealed by a 2.3-A resolution crystal structure of nerve growth factor
@ast
New protein fold revealed by a 2.3-A resolution crystal structure of nerve growth factor
@en
New protein fold revealed by a 2.3-A resolution crystal structure of nerve growth factor
@nl
prefLabel
New protein fold revealed by a 2.3-A resolution crystal structure of nerve growth factor
@ast
New protein fold revealed by a 2.3-A resolution crystal structure of nerve growth factor
@en
New protein fold revealed by a 2.3-A resolution crystal structure of nerve growth factor
@nl
P2093
P921
P3181
P356
P1433
P1476
New protein fold revealed by a 2.3-A resolution crystal structure of nerve growth factor
@en
P2093
A Wlodawer
J Murray-Rust
N Q McDonald
P2888
P3181
P356
10.1038/354411A0
P407
P50
P577
1991-12-05T00:00:00Z
P6179
1029870512