Substituted 3-(4-(1,3,5-triazin-2-yl)-phenyl)-2-aminopropanoic acids as novel tryptophan hydroxylase inhibitors

Substituted 3-(4-(1,3,5-triazin-2-yl)-phenyl)-2-aminopropanoic acids as novel tryptophan hydroxylase inhibitors

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http://www.wikidata.org/entity/Q27656714
Mechanism of Inhibition of Novel Tryptophan Hydroxylase Inhibitors Revealed by Co-crystal Structures and Kinetic AnalysisMolecular dynamics simulation of tryptophan hydroxylase-1: binding modes and free energy analysis to phenylalanine derivative inhibitorsCombined structure-based pharmacophore and 3D-QSAR studies on phenylalanine series compounds as TPH1 inhibitorsPharmacological reduction of mucosal but not neuronal serotonin opposes inflammation in mouse intestine.LX-1031, a tryptophan 5-hydroxylase inhibitor, and its potential in chronic diarrhea associated with increased serotoninHigh-throughput screening of mouse gene knockouts identifies established and novel skeletal phenotypes.Adult Tph2 knockout mice without brain serotonin have moderately elevated spine trabecular bone but moderately low cortical bone thicknessGene therapy by targeted adenovirus-mediated knockdown of pulmonary endothelial Tph1 attenuates hypoxia-induced pulmonary hypertension.Pharmacology of the new treatments for lower gastrointestinal motility disorders and irritable bowel syndrome.Inhibition of Peripheral Synthesis of Serotonin as a New Target in Neuroendocrine Tumors.Stabilization of tryptophan hydroxylase 2 by l-phenylalanine-induced dimerization.
P2860

Substituted 3-(4-(1,3,5-triazin-2-yl)-phenyl)-2-aminopropanoic acids as novel tryptophan hydroxylase inhibitors

Item
http://www.wikidata.org/entity/Q27656714
description
2009 nî lūn-bûn
@nan
2009 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Substituted 3-(4-(1,3,5-triazi ...... ptophan hydroxylase inhibitors
@ast
Substituted 3-(4-(1,3,5-triazi ...... ptophan hydroxylase inhibitors
@en
Substituted 3-(4-(1,3,5-triazi ...... ptophan hydroxylase inhibitors
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type
label
Substituted 3-(4-(1,3,5-triazi ...... ptophan hydroxylase inhibitors
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Substituted 3-(4-(1,3,5-triazi ...... ptophan hydroxylase inhibitors
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Substituted 3-(4-(1,3,5-triazi ...... ptophan hydroxylase inhibitors
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prefLabel
Substituted 3-(4-(1,3,5-triazi ...... ptophan hydroxylase inhibitors
@ast
Substituted 3-(4-(1,3,5-triazi ...... ptophan hydroxylase inhibitors
@en
Substituted 3-(4-(1,3,5-triazi ...... ptophan hydroxylase inhibitors
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P1433
P1476
Substituted 3-(4-(1,3,5-triazi ...... ptophan hydroxylase inhibitors
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P2093
P304
P31
P3181
P356
10.1016/J.BMCL.2009.07.005
P407
P433
P478
P577
P698