X-ray crystallography reveals a reduced substrate complex of UDP-galactopyranose mutase poised for covalent catalysis by flavin - Wikidata - awgldk - TriplyDB

X-ray crystallography reveals a reduced substrate complex of UDP-galactopyranose mutase poised for covalent catalysis by flavin

X-ray crystallography reveals a reduced substrate complex of UDP-galactopyranose mutase poised for covalent catalysis by flavin

http://www.wikidata.org/entity/Q27657238

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The structural biology of enzymes involved in natural product glycosylation Targeting UDP-galactopyranose mutases from eukaryotic human pathogens Flavoenzymes: versatile catalysts in biosynthetic pathways Virtual Screening for UDP-Galactopyranose Mutase Ligands Identifies a New Class of Antimycobacterial Agents Identification of the NAD(P)H Binding Site of Eukaryotic UDP-Galactopyranose Mutase Precursor of ether phospholipids is synthesized by a flavoenzyme through covalent catalysis Crystal Structures and Small-angle X-ray Scattering Analysis of UDP-galactopyranose Mutase from the Pathogenic Fungus Aspergillus fumigatus Structural Insight into the Unique Substrate Binding Mechanism and Flavin Redox State of UDP-galactopyranose Mutase from Aspergillus fumigatus Crystal Structures of Trypanosoma cruzi UDP-Galactopyranose Mutase Implicate Flexibility of the Histidine Loop in Enzyme Activation Specificity of a UDP-GalNAc pyranose-furanose mutase: a potential therapeutic target for Campylobacter jejuni infections Chemical mechanism of UDP-galactopyranose mutase from Trypanosoma cruzi: a potential drug target against Chagas' disease Characterization of a bifunctional pyranose-furanose mutase from Campylobacter jejuni 11168.Study of Uridine 5'-Diphosphate (UDP)-Galactopyranose Mutase Using UDP-5-Fluorogalactopyranose as a Probe: Incubation Results and Mechanistic Implications.Purification, crystallization and preliminary X-ray diffraction data of UDP-galactopyranose mutase from Aspergillus fumigatus Contributions of unique active site residues of eukaryotic UDP-galactopyranose mutases to substrate recognition and active site dynamics.QM/MM molecular dynamics study of the galactopyranose → galactofuranose reaction catalysed by Trypanosoma cruzi UDP-galactopyranose mutase.Nucleophilic participation of reduced flavin coenzyme in mechanism of UDP-galactopyranose mutase.Towards the crystal structure elucidation of eukaryotic UDP-galactopyranose mutase Noncanonical reactions of flavoenzymes.In Crystallo Capture of a Covalent Intermediate in the UDP-Galactopyranose Mutase Reaction.UDP-galactopyranose mutase in nematodes.Structure, mechanism, and dynamics of UDP-galactopyranose mutase.Crystal structure and enzymatic characterization of thymidylate synthase X from Helicobacter pylori strain SS1.Deciphering the sugar biosynthetic pathway and tailoring steps of nucleoside antibiotic A201A unveils a GDP-l-galactose mutase.UDP-galactopyranose mutases from Leishmania species that cause visceral and cutaneous leishmaniasis.Multiple functionalities of reduced flavin in the non-redox reaction catalyzed by UDP-galactopyranose mutase.Biosynthesis of galactofuranose in kinetoplastids: novel therapeutic targets for treating leishmaniasis and chagas' disease.Conformational Control of UDP-Galactopyranose Mutase Inhibition.The Cell Wall Arabinose-Deficient Arabidopsis thaliana Mutant murus5 Encodes a Defective Allele of REVERSIBLY GLYCOSYLATED POLYPEPTIDE2.A Second, Druggable Binding Site in UDP-Galactopyranose Mutase from Mycobacterium tuberculosis?

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P2860

X-ray crystallography reveals a reduced substrate complex of UDP-galactopyranose mutase poised for covalent catalysis by flavin

http://www.wikidata.org/entity/Q27657238

description

2009 nî lūn-bûn

@nan

2009 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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name

X-ray Crystallography Reveals ...... Covalent Catalysis by Flavin,

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X-ray crystallography reveals ...... r covalent catalysis by flavin

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X-ray crystallography reveals ...... r covalent catalysis by flavin

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type

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X-ray Crystallography Reveals ...... Covalent Catalysis by Flavin,

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X-ray crystallography reveals ...... r covalent catalysis by flavin

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X-ray crystallography reveals ...... r covalent catalysis by flavin

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prefLabel

X-ray Crystallography Reveals ...... Covalent Catalysis by Flavin,

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X-ray crystallography reveals ...... r covalent catalysis by flavin

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X-ray crystallography reveals ...... r covalent catalysis by flavin

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X-ray crystallography reveals ...... r covalent catalysis by flavin

@en

P2093

Katrina T Forest

http://www.w3.org/2001/XMLSchema#string

Laura L Kiessling

http://www.w3.org/2001/XMLSchema#string

Todd D Gruber

http://www.w3.org/2001/XMLSchema#string

William M Westler

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P2860

Crystal structure of reduced thioredoxin reductase from Escherichia coli: Structural flexibility in the isoalloxazine ring of the flavin adenine dinucleotide cofactor

UDP-galactopyranose mutase has a novel structure and mechanism

Ligand Binding and Substrate Discrimination by UDP-Galactopyranose Mutase

The chemical and biological versatility of riboflavin

A unique catalytic mechanism for UDP-galactopyranose mutase.

Cation-pi interactions in ligand recognition and catalysis.

Galactofuranose metabolism: a potential target for antimicrobial chemotherapy.

Contribution of galactofuranose to the virulence of the opportunistic pathogen Aspergillus fumigatus

Investigation of binding of UDP-Galf and UDP-[3-F]Galf to UDP-galactopyranose mutase by STD-NMR spectroscopy, molecular dynamics, and CORCEMA-ST calculations.

Site-directed mutagenesis of UDP-galactopyranose mutase reveals a critical role for the active-site, conserved arginine residues.

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9171-9173

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scholarly article

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10.1021/BI901437V

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39

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48

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26778926

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19719175

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X-ray crystallography

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2785223

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