A unique catalytic mechanism for UDP-galactopyranose mutase.
about
Phylogenetic framework and molecular signatures for the main clades of the phylum Actinobacteria.The structural biology of enzymes involved in natural product glycosylationTargeting UDP-galactopyranose mutases from eukaryotic human pathogensFlavoenzymes: versatile catalysts in biosynthetic pathwaysNew Role of Flavin as a General Acid-Base Catalyst with No Redox Function in Type 2 Isopentenyl-diphosphate IsomeraseLigand Binding and Substrate Discrimination by UDP-Galactopyranose MutaseX-ray crystallography reveals a reduced substrate complex of UDP-galactopyranose mutase poised for covalent catalysis by flavinVirtual Screening for UDP-Galactopyranose Mutase Ligands Identifies a New Class of Antimycobacterial AgentsIdentification of the NAD(P)H Binding Site of Eukaryotic UDP-Galactopyranose MutaseCrystal Structures and Small-angle X-ray Scattering Analysis of UDP-galactopyranose Mutase from the Pathogenic Fungus Aspergillus fumigatusCrystal Structures of Trypanosoma cruzi UDP-Galactopyranose Mutase Implicate Flexibility of the Histidine Loop in Enzyme ActivationSpecificity of a UDP-GalNAc pyranose-furanose mutase: a potential therapeutic target for Campylobacter jejuni infectionsChemical mechanism of UDP-galactopyranose mutase from Trypanosoma cruzi: a potential drug target against Chagas' diseaseCharacterization of a bifunctional pyranose-furanose mutase from Campylobacter jejuni 11168.Study of Uridine 5'-Diphosphate (UDP)-Galactopyranose Mutase Using UDP-5-Fluorogalactopyranose as a Probe: Incubation Results and Mechanistic Implications.Eukaryotic UDP-galactopyranose mutase (GLF gene) in microbial and metazoal pathogens.Bases of biocontrol: sequence predicts synthesis and mode of action of agrocin 84, the Trojan horse antibiotic that controls crown gallA plant mutase that interconverts UDP-arabinofuranose and UDP-arabinopyranose.The diverse roles of flavin coenzymes--nature's most versatile thespians.Contributions of unique active site residues of eukaryotic UDP-galactopyranose mutases to substrate recognition and active site dynamics.QM/MM molecular dynamics study of the galactopyranose → galactofuranose reaction catalysed by Trypanosoma cruzi UDP-galactopyranose mutase.3-Sulfinopropionyl-coenzyme A (3SP-CoA) desulfinase from Advenella mimigardefordensis DPN7(T): crystal structure and function of a desulfinase with an acyl-CoA dehydrogenase foldNucleophilic participation of reduced flavin coenzyme in mechanism of UDP-galactopyranose mutase.Noncanonical reactions of flavoenzymes.In Crystallo Capture of a Covalent Intermediate in the UDP-Galactopyranose Mutase Reaction.UDP-galactopyranose mutase in nematodes.Investigation of binding of UDP-Galf and UDP-[3-F]Galf to UDP-galactopyranose mutase by STD-NMR spectroscopy, molecular dynamics, and CORCEMA-ST calculations.Structure, mechanism, and dynamics of UDP-galactopyranose mutase.Mechanisms and inhibition of uracil methylating enzymes.Synthesis of D-galactofuranose-containing molecules: design of galactofuranosyl acceptors.Expression and initial characterization of WbbI, a putative D-Galf:alpha-D-Glc beta-1,6-galactofuranosyltransferase from Escherichia coli K-12.Deciphering the sugar biosynthetic pathway and tailoring steps of nucleoside antibiotic A201A unveils a GDP-l-galactose mutase.UDP-galactopyranose mutases from Leishmania species that cause visceral and cutaneous leishmaniasis.Comparing Galactan Biosynthesis in Mycobacterium tuberculosis and Corynebacterium diphtheriae.Revisitation of the βCl-elimination reaction of D-amino acid oxidase: new interpretation of the reaction that sparked flavoprotein dehydrogenation mechanisms.Carboxylate Surrogates Enhance the Antimycobacterial Activity of UDP-Galactopyranose Mutase Probes.Multiple functionalities of reduced flavin in the non-redox reaction catalyzed by UDP-galactopyranose mutase.Synthetic UDP-furanoses as potent inhibitors of mycobacterial galactan biogenesis.Natural and Synthetic Flavonoids as Potent Mycobacterium tuberculosis UGM Inhibitors.Sugar nucleotide recognition by Klebsiella pneumoniae UDP-D-galactopyranose mutase: fluorinated substrates, kinetics and equilibria.
P2860
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P2860
A unique catalytic mechanism for UDP-galactopyranose mutase.
description
2004 nî lūn-bûn
@nan
2004 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
A unique catalytic mechanism for UDP-galactopyranose mutase.
@ast
A unique catalytic mechanism for UDP-galactopyranose mutase.
@en
A unique catalytic mechanism for UDP-galactopyranose mutase.
@nl
type
label
A unique catalytic mechanism for UDP-galactopyranose mutase.
@ast
A unique catalytic mechanism for UDP-galactopyranose mutase.
@en
A unique catalytic mechanism for UDP-galactopyranose mutase.
@nl
prefLabel
A unique catalytic mechanism for UDP-galactopyranose mutase.
@ast
A unique catalytic mechanism for UDP-galactopyranose mutase.
@en
A unique catalytic mechanism for UDP-galactopyranose mutase.
@nl
P2093
P2860
P356
P1476
A unique catalytic mechanism for UDP-galactopyranose mutase.
@en
P2093
Erin E Carlson
Michelle Soltero-Higgin
Todd D Gruber
P2860
P2888
P304
P356
10.1038/NSMB772
P577
2004-05-09T00:00:00Z