Atomic substitution reveals the structural basis for substrate adenine recognition and removal by adenine DNA glycosylase
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MUTYH DNA glycosylase: the rationale for removing undamaged bases from the DNAThe formamidopyrimidines: purine lesions formed in competition with 8-oxopurines from oxidative stressA Structural Hinge in Eukaryotic MutY Homologues Mediates Catalytic Activity and Rad9–Rad1–Hus1 Checkpoint Complex InteractionsExcision of thymine and 5-hydroxymethyluracil by the MBD4 DNA glycosylase domain: structural basis and implications for active DNA demethylationExcision of 5-hydroxymethyluracil and 5-carboxylcytosine by the thymine DNA glycosylase domain: its structural basis and implications for active DNA demethylationCrystal Structure of Human Methyl-Binding Domain IV Glycosylase Bound to Abasic DNAStructural basis of damage recognition by thymine DNA glycosylase: Key roles for N-terminal residuesRole of base excision repair in maintaining the genetic and epigenetic integrity of CpG sitesSpecificity and catalytic mechanism in family 5 uracil DNA glycosylaseThymine DNA glycosylase exhibits negligible affinity for nucleobases that it removes from DNAStructure and stereochemistry of the base excision repair glycosylase MutY reveal a mechanism similar to retaining glycosidasesElectrochemistry of the [4Fe4S] Cluster in Base Excision Repair Proteins: Tuning the Redox Potential with DNA.Ser 524 is a phosphorylation site in MUTYH and Ser 524 mutations alter 8-oxoguanine (OG): a mismatch recognition.Recent advances in the structural mechanisms of DNA glycosylasesGas-phase studies of substrates for the DNA mismatch repair enzyme MutY.Catalytic contributions of key residues in the adenine glycosylase MutY revealed by pH-dependent kinetics and cellular repair assays.Structural Basis for Avoidance of Promutagenic DNA Repair by MutY Adenine DNA GlycosylaseCoordination of MYH DNA glycosylase and APE1 endonuclease activities via physical interactions.Distinct functional consequences of MUTYH variants associated with colorectal cancer: Damaged DNA affinity, glycosylase activity and interaction with PCNA and Hus1.Mechanisms for enzymatic cleavage of the N-glycosidic bond in DNA.Structural Basis for Excision of 5-Formylcytosine by Thymine DNA Glycosylase.Role of Base Excision "Repair" Enzymes in Erasing Epigenetic Marks from DNARepair of 8-oxoG:A mismatches by the MUTYH glycosylase: Mechanism, metals and medicine.Base excision repair of oxidative DNA damage: from mechanism to disease.Dispensability of the [4Fe-4S] cluster in novel homologues of adenine glycosylase MutY.A zinc linchpin motif in the MUTYH glycosylase interdomain connector is required for efficient repair of DNA damage.Structure-Activity Relationships Reveal Key Features of 8-Oxoguanine: A Mismatch Detection by the MutY Glycosylase.MUTYH-associated polyposis (MAP), the syndrome implicating base excision repair in inherited predisposition to colorectal tumors.Structural Basis for the Lesion-scanning Mechanism of the MutY DNA Glycosylase.
P2860
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P2860
Atomic substitution reveals the structural basis for substrate adenine recognition and removal by adenine DNA glycosylase
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2009 nî lūn-bûn
@nan
2009 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Atomic substitution reveals th ...... val by adenine DNA glycosylase
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Atomic substitution reveals th ...... val by adenine DNA glycosylase
@en
Atomic substitution reveals th ...... val by adenine DNA glycosylase
@nl
type
label
Atomic substitution reveals th ...... val by adenine DNA glycosylase
@ast
Atomic substitution reveals th ...... val by adenine DNA glycosylase
@en
Atomic substitution reveals th ...... val by adenine DNA glycosylase
@nl
prefLabel
Atomic substitution reveals th ...... val by adenine DNA glycosylase
@ast
Atomic substitution reveals th ...... val by adenine DNA glycosylase
@en
Atomic substitution reveals th ...... val by adenine DNA glycosylase
@nl
P2860
P3181
P356
P1476
Atomic substitution reveals th ...... val by adenine DNA glycosylase
@en
P2093
Gregory L Verdine
Seongmin Lee
P2860
P304
P3181
P356
10.1073/PNAS.0902908106
P407
P577
2009-11-03T00:00:00Z