The Crystal Structures of Yeast Get3 Suggest a Mechanism for Tail-Anchored Protein Membrane Insertion
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A ribosome-associating factor chaperones tail-anchored membrane proteinsEndoplasmic reticulum targeting and insertion of tail-anchored membrane proteins by the GET pathwayThe structure of Get4 reveals an alpha-solenoid fold adapted for multiple interactions in tail-anchored protein biogenesisStructural characterization of the Get4/Get5 complex and its interaction with Get3A Conserved Archaeal Pathway for Tail-Anchored Membrane Protein InsertionStructural Basis for Tail-Anchored Membrane Protein Biogenesis by the Get3-Receptor ComplexThe mechanism of membrane-associated steps in tail-anchored protein insertionTail-anchor targeting by a Get3 tetramer: the structure of an archaeal homologueCrystal structure of ATP-bound Get3–Get4–Get5 complex reveals regulation of Get3 by Get4A chaperone cascade sorts proteins for posttranslational membrane insertion into the endoplasmic reticulum.The protein targeting factor Get3 functions as ATP-independent chaperone under oxidative stress conditions.Membrane protein insertion at the endoplasmic reticulum.A conserved amphipathic helix is required for membrane tubule formation by Yop1pInteraction surface and topology of Get3-Get4-Get5 protein complex, involved in targeting tail-anchored proteins to endoplasmic reticulum.Nucleotide-dependent mechanism of Get3 as elucidated from free energy calculations.The complex process of GETting tail-anchored membrane proteins to the ER.Development of a prediction system for tail-anchored proteinsMechanism of Assembly of a Substrate Transfer Complex during Tail-anchored Protein Targeting.Structures of Get3, Get4, and Get5 provide new models for TA membrane protein targetingPrecise timing of ATPase activation drives targeting of tail-anchored proteins.Tail-anchored membrane protein insertion into the endoplasmic reticulum.Bag6/Bat3/Scythe: a novel chaperone activity with diverse regulatory functions in protein biogenesis and degradation.All roads lead to Rome (but some may be harder to travel): SRP-independent translocation into the endoplasmic reticulum.The emerging role of calcium-modulating cyclophilin ligand in posttranslational insertion of tail-anchored proteins into the endoplasmic reticulum membrane.A biochemical analysis of the constraints of tail-anchored protein biogenesis.Protein targeting. Structure of the Get3 targeting factor in complex with its membrane protein cargo.Bat3 promotes the membrane integration of tail-anchored proteins.Tail-Anchored Protein Insertion by a Single Get1/2 Heterodimer.Biogenesis of photosynthetic complexes in the chloroplast of Chlamydomonas reinhardtii requires ARSA1, a homolog of prokaryotic arsenite transporter and eukaryotic TRC40 for guided entry of tail-anchored proteins.The GET System Inserts the Tail-Anchored Protein, SYP72, into Endoplasmic Reticulum Membranes.
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P2860
The Crystal Structures of Yeast Get3 Suggest a Mechanism for Tail-Anchored Protein Membrane Insertion
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2009 nî lūn-bûn
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2009 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի նոյեմբերին հրատարակված գիտական հոդված
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2009年の論文
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2009年論文
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2009年論文
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2009年論文
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2009年論文
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2009年論文
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2009年论文
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The Crystal Structures of Yeas ...... red Protein Membrane Insertion
@ast
The Crystal Structures of Yeas ...... red Protein Membrane Insertion
@en
The Crystal Structures of Yeas ...... red Protein Membrane Insertion
@nl
type
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The Crystal Structures of Yeas ...... red Protein Membrane Insertion
@ast
The Crystal Structures of Yeas ...... red Protein Membrane Insertion
@en
The Crystal Structures of Yeas ...... red Protein Membrane Insertion
@nl
prefLabel
The Crystal Structures of Yeas ...... red Protein Membrane Insertion
@ast
The Crystal Structures of Yeas ...... red Protein Membrane Insertion
@en
The Crystal Structures of Yeas ...... red Protein Membrane Insertion
@nl
P2093
P2860
P3181
P1433
P1476
The Crystal Structures of Yeas ...... red Protein Membrane Insertion
@en
P2093
Bingdong Sha
Jingzhi Li
Vlad Denic
Xinguo Qian
P2860
P3181
P356
10.1371/JOURNAL.PONE.0008061
P407
P577
2009-11-30T00:00:00Z