Macrocyclic BACE-1 inhibitors acutely reduce Abeta in brain after po application

Macrocyclic BACE-1 inhibitors acutely reduce Abeta in brain after po application

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http://www.wikidata.org/entity/Q27658444
Flexibility of the flap in the active site of BACE1 as revealed by crystal structures and molecular dynamics simulationsDiscovery of a Novel Class of Imidazo[1,2-a]Pyridines with Potent PDGFR Activity and Oral Bioavailability.BACE1 (β-secretase) inhibitors for the treatment of Alzheimer's diseaseDeveloping β-secretase inhibitors for treatment of Alzheimer's disease.Mechanisms that lessen benefits of β-secretase reduction in a mouse model of Alzheimer's disease.Beta-secretase as a target for Alzheimer's disease drug discovery: an overview of in vitro methods for characterization of inhibitors.The recent updates of therapeutic approaches against aβ for the treatment of Alzheimer's disease.Small-molecule BACE1 inhibitors: a patent literature review (2006 - 2011).Animal models of Alzheimer disease.The structural evolution of β-secretase inhibitors: a focus on the development of small-molecule inhibitors.Macrocyclic olefin metathesis at high concentrations by using a phase-separation strategy.Chemometric design to explore pharmacophore features of BACE inhibitors for controlling Alzheimer's disease.The BACE-1 inhibitor CNP520 for prevention trials in Alzheimer's disease
P2860

Macrocyclic BACE-1 inhibitors acutely reduce Abeta in brain after po application

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http://www.wikidata.org/entity/Q27658444
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2010 nî lūn-bûn
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2010 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Macrocyclic BACE-1 inhibitors acutely reduce Abeta in brain after po application
@ast
Macrocyclic BACE-1 inhibitors acutely reduce Abeta in brain after po application
@en
Macrocyclic BACE-1 inhibitors acutely reduce Abeta in brain after po application
@nl
type
label
Macrocyclic BACE-1 inhibitors acutely reduce Abeta in brain after po application
@ast
Macrocyclic BACE-1 inhibitors acutely reduce Abeta in brain after po application
@en
Macrocyclic BACE-1 inhibitors acutely reduce Abeta in brain after po application
@nl
prefLabel
Macrocyclic BACE-1 inhibitors acutely reduce Abeta in brain after po application
@ast
Macrocyclic BACE-1 inhibitors acutely reduce Abeta in brain after po application
@en
Macrocyclic BACE-1 inhibitors acutely reduce Abeta in brain after po application
@nl
P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P921
P356
P1433
P1476
Macrocyclic BACE-1 inhibitors acutely reduce Abeta in brain after po application
@en
P2093
P304
P31
P356
10.1016/J.BMCL.2009.11.092
P407
P433
P478
P50
P577
P5875
P698
P921