Large-scale Domain Dynamics and Adenosylcobalamin Reorientation Orchestrate Radical Catalysis in Ornithine 4,5-Aminomutase
about
High-resolution crystal structure of the eukaryotic HMP-P synthase (THIC) from Arabidopsis thalianaA mechanochemical switch to control radical intermediates.A conformational sampling model for radical catalysis in pyridoxal phosphate- and cobalamin-dependent enzymes.Structural diversity in the AdoMet radical enzyme superfamily.Large-scale domain motions and pyridoxal-5'-phosphate assisted radical catalysis in coenzyme B12-dependent aminomutases.Vitamin B12-derivatives-enzyme cofactors and ligands of proteins and nucleic acids.Kinetic and spectroscopic probes of motions and catalysis in the cytochrome P450 reductase family of enzymes.Adenosylcobalamin enzymes: theory and experiment begin to convergeRelating localized protein motions to the reaction coordinate in coenzyme B₁₂-dependent enzymes.Molecular architectures and functions of radical enzymes and their (re)activating proteins.Orchestrated Domain Movement in Catalysis by Cytochrome P450 Reductase.Glutamate 338 is an electrostatic facilitator of C-Co bond breakage in a dynamic/electrostatic model of catalysis by ornithine aminomutase.Redox-linked domain movements in the catalytic cycle of cytochrome p450 reductase.Dynamic, electrostatic model for the generation and control of high-energy radical intermediates by a coenzyme B₁₂-dependent enzyme.Role of active site residues in promoting cobalt-carbon bond homolysis in adenosylcobalamin-dependent mutases revealed through experiment and computation.Unraveling the Mechanism and Regioselectivity of the B12-Dependent Reductive Dehalogenase PceA.Protein motions are coupled to the reaction chemistry in coenzyme B12-dependent ethanolamine ammonia lyase.Quantum Mechanics/Molecular Mechanics Studies on the Mechanism of Action of Cofactor Pyridoxal 5′-Phosphate in Ornithine 4,5-Aminomutase
P2860
Q27687359-3D3CEACD-CE49-4D0F-AAB8-A650D97F864AQ33792779-CC1EF460-DEF5-4F7A-A6F4-80F3B50540D4Q34634262-456525C1-3D51-4DE1-88F2-814FF73966F6Q36469251-59B86AB3-9EEB-45F4-A89D-6B886C4F028FQ37645381-DA2BE727-4B16-4F1E-A5E4-6F9A00B2479DQ37891827-D981AF66-0F1B-473A-91EF-9B73D08A3A33Q37964804-2487FC94-DE83-452B-A5B5-BD4BED43B21AQ38003770-E20D127F-DB6C-4892-9194-764008AF706EQ38086666-CBB735D5-07CA-4755-B6AB-B1ECF4B0ABB7Q38564134-2EE22A7B-9464-41DE-8E14-5FF122A012C5Q38603029-B8FC56F8-926D-4244-A68B-5493492394B6Q40031683-BB7FD494-2695-4DBF-97AE-1C2B612DAC91Q41808959-3DD5E087-0145-455C-80A4-38E27468826EQ41865658-BCFF10C9-A0B3-4424-81E4-D8CD0B3FC8FEQ41963377-B4EFA31C-2950-44F0-9D4F-A1F6CCFFEF58Q48055234-B2658D28-87AC-40F9-BB26-019D815D08EBQ50025110-F9E84236-025C-4DA3-8A6E-C185B3C41D71Q57015760-126692E3-2F3F-418D-97A4-8FCBDBF33A57
P2860
Large-scale Domain Dynamics and Adenosylcobalamin Reorientation Orchestrate Radical Catalysis in Ornithine 4,5-Aminomutase
description
2010 nî lūn-bûn
@nan
2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Large-scale Domain Dynamics an ...... s in Ornithine 4,5-Aminomutase
@ast
Large-scale Domain Dynamics an ...... s in Ornithine 4,5-Aminomutase
@en
Large-scale Domain Dynamics an ...... s in Ornithine 4,5-Aminomutase
@nl
type
label
Large-scale Domain Dynamics an ...... s in Ornithine 4,5-Aminomutase
@ast
Large-scale Domain Dynamics an ...... s in Ornithine 4,5-Aminomutase
@en
Large-scale Domain Dynamics an ...... s in Ornithine 4,5-Aminomutase
@nl
prefLabel
Large-scale Domain Dynamics an ...... s in Ornithine 4,5-Aminomutase
@ast
Large-scale Domain Dynamics an ...... s in Ornithine 4,5-Aminomutase
@en
Large-scale Domain Dynamics an ...... s in Ornithine 4,5-Aminomutase
@nl
P2093
P2860
P356
P1476
Large-scale Domain Dynamics an ...... s in Ornithine 4,5-Aminomutase
@en
P2093
Colin Levy
Kirsten R Wolthers
Nigel S Scrutton
P2860
P304
P356
10.1074/JBC.M109.068908
P407
P50
P577
2010-04-30T00:00:00Z