Biochemical and Structural Characterization of Mycobacterium tuberculosis β-Lactamase with the Carbapenems Ertapenem and Doripenem
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Carbapenems: past, present, and futureStructures of the Michaelis Complex (1.2 Å) and the Covalent Acyl Intermediate (2.0 Å) of Cefamandole Bound in the Active Sites of the Mycobacterium tuberculosis β-Lactamase K73A and E166A Mutants,Structures of the Class D Carbapenemase OXA-24 from Acinetobacter baumannii in Complex with DoripenemThe Binding of Antibiotics in OmpF PorinNXL104 Irreversibly Inhibits the β-Lactamase from Mycobacterium tuberculosisCan Inhibitor-Resistant Substitutions in the Mycobacterium tuberculosis -Lactamase BlaC Lead to Clavulanate Resistance?: a Biochemical Rationale for the Use of -Lactam- -Lactamase Inhibitor CombinationsTebipenem, a New Carbapenem Antibiotic, Is a Slow Substrate That Inhibits the β-Lactamase from Mycobacterium tuberculosisKinetic and Structural Characterization of the Interaction of 6-Methylidene Penem 2 with the β-Lactamase from Mycobacterium tuberculosisClass D β-lactamases: a reappraisal after five decadesNew Insights in to the Intrinsic and Acquired Drug Resistance Mechanisms in MycobacteriaExploring the inhibition of CTX-M-9 by beta-lactamase inhibitors and carbapenems.Rapid point-of-care detection of the tuberculosis pathogen using a BlaC-specific fluorogenic probeClassification of Beta-lactamases and penicillin binding proteins using ligand-centric network models.Carbapenems and Rifampin Exhibit Synergy against Mycobacterium tuberculosis and Mycobacterium abscessus.Structural enzymology using X-ray free electron lasers.Elucidating the Role of Residue 67 in IMP-Type Metallo-β-Lactamase Evolution.Kinetic characterization of hydrolysis of nitrocefin, cefoxitin, and meropenem by β-lactamase from Mycobacterium tuberculosis.A kinetic analysis of the inhibition of FOX-4 β-lactamase, a plasmid-mediated AmpC cephalosporinase, by monocyclic β-lactams and carbapenemsReappraising the use of β-lactams to treat tuberculosis.Metallo-β-lactamase structure and function.Advances In Mycobacterium Tuberculosis Therapeutics Discovery Utlizing Structural Biology.Molecular biology of drug resistance in Mycobacterium tuberculosisβ-Lactam Resistance Mechanisms: Gram-Positive Bacteria and Mycobacterium tuberculosis.Antibiotic resistance mechanisms in M. tuberculosis: an update.Involvement of efflux pumps in the resistance to peptidoglycan synthesis inhibitors in Mycobacterium tuberculosisRecognizing drug targets using evolutionary information: implications for repurposing FDA-approved drugs against Mycobacterium tuberculosis H37Rv.The sequence-activity relationship between metallo-β-lactamases IMP-1, IMP-6, and IMP-25 suggests an evolutionary adaptation to meropenem exposure.The mechanism of NDM-1-catalyzed carbapenem hydrolysis is distinct from that of penicillin or cephalosporin hydrolysis.Modified Penicillin Molecule with Carbapenem-Like Stereochemistry Specifically Inhibits Class C β-Lactamases.A Tyrosine Residue Along with a Glutamic Acid of the Omega-Like Loop Governs the Beta-Lactamase Activity of MSMEG_4455 in Mycobacterium smegmatis.Inhibition studies on Mycobacterium tuberculosis N-acetylglucosamine-1-phosphate uridyltransferase (GlmU).Enzyme intermediates captured "on the fly" by mix-and-inject serial crystallography.Carbapenems as water soluble organocatalysts
P2860
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P2860
Biochemical and Structural Characterization of Mycobacterium tuberculosis β-Lactamase with the Carbapenems Ertapenem and Doripenem
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2010 nî lūn-bûn
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2010 թուականի Մայիսին հրատարակուած գիտական յօդուած
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2010 թվականի մայիսին հրատարակված գիտական հոդված
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2010年の論文
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2010年論文
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2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
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name
Biochemical and Structural Cha ...... penems Ertapenem and Doripenem
@ast
Biochemical and Structural Cha ...... penems Ertapenem and Doripenem
@en
Biochemical and Structural Cha ...... penems Ertapenem and Doripenem
@nl
type
label
Biochemical and Structural Cha ...... penems Ertapenem and Doripenem
@ast
Biochemical and Structural Cha ...... penems Ertapenem and Doripenem
@en
Biochemical and Structural Cha ...... penems Ertapenem and Doripenem
@nl
prefLabel
Biochemical and Structural Cha ...... penems Ertapenem and Doripenem
@ast
Biochemical and Structural Cha ...... penems Ertapenem and Doripenem
@en
Biochemical and Structural Cha ...... penems Ertapenem and Doripenem
@nl
P2093
P2860
P921
P356
P1433
P1476
Biochemical and Structural Cha ...... penems Ertapenem and Doripenem
@en
P2093
John S Blanchard
Lee W Tremblay
P2860
P304
P356
10.1021/BI100232Q
P407
P577
2010-05-04T00:00:00Z