Carbapenems, a new class of beta-lactam antibiotics. Discovery and development of imipenem/cilastatin - Wikidata - awgldk - TriplyDB

Carbapenems, a new class of beta-lactam antibiotics. Discovery and development of imipenem/cilastatin

Carbapenems, a new class of beta-lactam antibiotics. Discovery and development of imipenem/cilastatin

http://www.wikidata.org/entity/Q28305833

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Definition of the common and divergent steps in carbapenem β-lactam antibiotic biosynthesis Biochemical and Structural Characterization of Mycobacterium tuberculosis β-Lactamase with the Carbapenems Ertapenem and Doripenem Natural Variants of the KPC-2 Carbapenemase have Evolved Increased Catalytic Efficiency for Ceftazidime Hydrolysis at the Cost of Enzyme Stability Rapid identification of carbapenemase genes in gram-negative bacteria with an oligonucleotide microarray-based assay Effects of antibiotic therapy on Pseudomonas aeruginosa-induced lung injury in a rat model.Biochemical characterization of novel tetrahydrofuranyl 1beta-methylcarbapenems: stability to hydrolysis by renal dehydropeptidases and bacterial beta-lactamases, binding to penicillin binding proteins, and permeability properties.Pharmacokinetics of imipenem-cilastatin in critically ill patients undergoing continuous venovenous hemofiltration.Assessment of the role of renal organic anion transporters in drug-induced nephrotoxicity.Therapeutic effects of imipenem-cilastatin on experimental intrauterine infections in rats.Biliary excretion of imipenem-cilastatin in hospitalized patients.A prospective randomized trial of imipenem-cilastatin versus clindamycin/tobramycin in the treatment of intra-abdominal and pelvic infections Asymmetric catalysis: an enabling science Gap junction inhibition prevents drug-induced liver toxicity and fulminant hepatic failure.Pharmacokinetics and transplacental passage of imipenem during pregnancy.Carbapenems in the USA: focus on doripenem.Effects of treatment with antimicrobial agents on the human colonic microflora Identification of Streptococcus faecalis and Streptococcus faecium and susceptibility studies with newly developed antimicrobial agents Tentative interpretive criteria for in vitro antibacterial susceptibility testing with imipenem.Bibliometric analysis of global scientific research on carbapenem resistance (1986-2015)Molecular-targeted approaches to reduce renal accumulation of nephrotoxic drugs.Klebsiella pneumoniae carbapenemases in Enterobacteriaceae: history, evolution, and microbiology concerns.Antimicrobial therapy for the elderly patient.Extended spectrum β-lactamases, carbapenemases and mobile genetic elements responsible for antibiotics resistance in Gram-negative bacteria.Xenobiotic transporters and kidney injury.Imipenem-antibiotic monotherapy in juvenile cancer patients with neutropenia.In vitro antibacterial activity of LJC 11,036, an active metabolite of L-084, a new oral carbapenem antibiotic with potent antipneumococcal activity Imipenem monotherapy versus combination therapy in the management of mixed bacterial infection: a critical appraisal.In vitro activity against aerobic and anaerobic gram-positive and gram-negative bacteria and beta-lactamase stability of RS-533, a novel carbapenem.Renal dehydropeptidase-I stability of LJC 10,627, a new carbapenem antibiotic.Extended infusion versus intermittent infusion of imipenem in the treatment of ventilator-associated pneumonia.Inhibition by carbapenem antibiotic imipenem of intestinal absorption of valproic acid in rats.Cisplatin-induced renal inflammation is ameliorated by cilastatin nephroprotection.Structural Elucidation of β-Lactam Diastereoisomers through Ion Mobility Mass Spectrometry Studies and Theoretical Calculations.Carbapenem Resistance: A Review.Post-antibiotic effect of FK-037 and biapenem tested against five bacterial species.

P2860

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P2860

Carbapenems, a new class of beta-lactam antibiotics. Discovery and development of imipenem/cilastatin

http://www.wikidata.org/entity/Q28305833

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1985 nî lūn-bûn

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1985 թուականի Յունիսին հրատարակուած գիտական յօդուած

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1985年の論文

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The American Journal of Medicine

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F M Kahan

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Frederick M. Kahan

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H Kropp

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Helmut Kropp

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J Birnbaum

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J S MacDonald

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James S. Macdonald

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Jerome Birnbaum

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3-21

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3859213

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carbapenem antibiotic