Inhibitor-induced structural change in the HCV IRES domain IIa RNA
about
In Silico Design and Experimental Validation of siRNAs Targeting Conserved Regions of Multiple Hepatitis C Virus GenotypesStructurally conserved five nucleotide bulge determines the overall topology of the core domain of human telomerase RNAExperimentally Restrained Molecular Dynamics Simulations for Characterizing the Open States of Cytochrome P450 camMolecular dynamics re-refinement of two different small RNA loop structures using the original NMR data suggest a common structureStructural and energetic analysis of 2-aminobenzimidazole inhibitors in complex with the hepatitis C virus IRES RNA using molecular dynamics simulations.Advancing viral RNA structure prediction: measuring the thermodynamics of pyrimidine-rich internal loopsSimplified RNA secondary structure mapping by automation of SHAPE data analysis.Hepatitis C virus translation inhibitors targeting the internal ribosomal entry site.RNA structural elements of hepatitis C virus controlling viral RNA translation and the implications for viral pathogenesis.HCV IRES-mediated core expression in zebrafish.HCV IRES domain IIb affects the configuration of coding RNA in the 40S subunit's decoding groove.Structure of a hepatitis C virus RNA domain in complex with a translation inhibitor reveals a binding mode reminiscent of riboswitchesFactors that influence T box riboswitch efficacy and tRNA affinity.Coarse grained models reveal essential contributions of topological constraints to the conformational free energy of RNA bulges.Hepatitis C viral protein translation: mechanisms and implications in developing antivirals.Tinkering with translation: protein synthesis in virus-infected cells.Understanding the potential of hepatitis C virus internal ribosome entry site domains to modulate translation initiation via their structure and function.Molecular modeling of nucleic Acid structure: electrostatics and solvation.Refinement of the Cornell et al. Nucleic Acids Force Field Based on Reference Quantum Chemical Calculations of Glycosidic Torsion Profiles.Identification of Spermidine Binding Site in T-box Riboswitch Antiterminator RNA.Cis-regulatory RNA elements that regulate specialized ribosome activity.Discovery of the 2-phenyl-4,5,6,7-Tetrahydro-1H-indole as a novel anti-hepatitis C virus targeting scaffold.Measuring antiviral activity of benzimidazole molecules that alter IRES RNA structure with an infectious hepatitis C virus chimera expressing Renilla luciferase.HnRNP A1 Alters the Structure of a Conserved Enterovirus IRES Domain to Stimulate Viral Translation.Local RNA flexibility perturbation of the IRES element induced by a novel ligand inhibits viral RNA translation.Computational study of the structural plasticity and the ligand binding affinity of the IRES subdomain IIa.Synthesis and stereospecificity of 4,5-disubstituted oxazolidinone ligands binding to T-box riboswitch RNA.Viral internal ribosomal entry sites: four classes for one goal.
P2860
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P2860
Inhibitor-induced structural change in the HCV IRES domain IIa RNA
description
2010 nî lūn-bûn
@nan
2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Inhibitor-induced structural change in the HCV IRES domain IIa RNA
@ast
Inhibitor-induced structural change in the HCV IRES domain IIa RNA
@en
Inhibitor-induced structural change in the HCV IRES domain IIa RNA
@nl
type
label
Inhibitor-induced structural change in the HCV IRES domain IIa RNA
@ast
Inhibitor-induced structural change in the HCV IRES domain IIa RNA
@en
Inhibitor-induced structural change in the HCV IRES domain IIa RNA
@nl
prefLabel
Inhibitor-induced structural change in the HCV IRES domain IIa RNA
@ast
Inhibitor-induced structural change in the HCV IRES domain IIa RNA
@en
Inhibitor-induced structural change in the HCV IRES domain IIa RNA
@nl
P2093
P2860
P3181
P356
P1476
Inhibitor-induced structural change in the HCV IRES domain IIa RNA
@en
P2093
Darrell R Davis
Eric E Swayze
Jack J Skalicky
Punit P Seth
Richard H Griffey
Ryan B Paulsen
P2860
P304
P3181
P356
10.1073/PNAS.0911896107
P407
P577
2010-04-20T00:00:00Z