Fragment-based discovery and optimization of BACE1 inhibitors
about
Flexibility of the flap in the active site of BACE1 as revealed by crystal structures and molecular dynamics simulationsAdvances in the identification of β-secretase inhibitors.Creation of Novel Cores for β-Secretase (BACE-1) Inhibitors: A Multiparameter Lead Generation Strategy.Stacking with No Planarity?Effect of pH and ligand charge state on BACE-1 fragment docking performance.Investigation of the interactions between aptamer and misfolded proteins: From monomer and oligomer to fibril by single-molecule force spectroscopy.Chemometric design to explore pharmacophore features of BACE inhibitors for controlling Alzheimer's disease.
P2860
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P2860
Fragment-based discovery and optimization of BACE1 inhibitors
description
2010 nî lūn-bûn
@nan
2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Fragment-based discovery and optimization of BACE1 inhibitors
@ast
Fragment-based discovery and optimization of BACE1 inhibitors
@en
Fragment-based discovery and optimization of BACE1 inhibitors
@nl
type
label
Fragment-based discovery and optimization of BACE1 inhibitors
@ast
Fragment-based discovery and optimization of BACE1 inhibitors
@en
Fragment-based discovery and optimization of BACE1 inhibitors
@nl
prefLabel
Fragment-based discovery and optimization of BACE1 inhibitors
@ast
Fragment-based discovery and optimization of BACE1 inhibitors
@en
Fragment-based discovery and optimization of BACE1 inhibitors
@nl
P2093
P1476
Fragment-based discovery and optimization of BACE1 inhibitors
@en
P2093
David J Hallett
James Madden
Jane D Dyekjaer
Jenny R Dod
Joachim Kraemer
John Barker
Marion Biniszkiewicz
Myron Smith
Robert Godemann
Thomas Hesterkamp
P304
P356
10.1016/J.BMCL.2010.06.089
P407
P577
2010-09-01T00:00:00Z