Structural and Functional Basis of Resistance to Neuraminidase Inhibitors of Influenza B Viruses
about
A generic system for the expression and purification of soluble and stable influenza neuraminidaseNeuraminidase inhibitors for influenza B virus infection: efficacy and resistanceMechanism-based covalent neuraminidase inhibitors with broad-spectrum influenza antiviral activityInfluenza neuraminidase inhibitors: antiviral action and mechanisms of resistanceI222 Neuraminidase mutations further reduce oseltamivir susceptibility of Indonesian Clade 2.1 highly pathogenic Avian Influenza A(H5N1) virusesTaking down the FLAG! How insect cell expression challenges an established tag-systemCrystalDock: a novel approach to fragment-based drug design.In vitro passaging of a pandemic H1N1/09 virus selects for viruses with neuraminidase mutations conferring high-level resistance to oseltamivir and peramivir, but not to zanamivir.Recent advances in neuraminidase inhibitor development as anti-influenza drugs.Real time enzyme inhibition assays provide insights into differences in binding of neuraminidase inhibitors to wild type and mutant influenza virusesMolecular epidemiology and phylogenetic analyses of influenza B virus in Thailand during 2010 to 2014.Competitive fitness of influenza B viruses with neuraminidase inhibitor-resistant substitutions in a coinfection model of the human airway epitheliumEpidemiological and Evolutionary Dynamics of Influenza B Viruses in Malaysia, 2012-2014Reduced susceptibility to all neuraminidase inhibitors of influenza H1N1 viruses with haemagglutinin mutations and mutations in non-conserved residues of the neuraminidase.Influenza neuraminidase: a druggable target for natural products.The chemistry and biology of organic guanidine derivatives.A review of neuraminidase inhibitor susceptibility in influenza strains.Empirical power laws for the radii of gyration of protein oligomers.A surface plasmon resonance assay for measurement of neuraminidase inhibition, sensitivity of wild-type influenza neuraminidase and its H274Y mutant to the antiviral drugs zanamivir and oseltamivir.Development of a surface plasmon resonance assay to measure the binding affinity of wild-type influenza neuraminidase and its H274Y mutant to the antiviral drug zanamivir.A 3D-RISM/RISM study of the oseltamivir binding efficiency with the wild-type and resistance-associated mutant forms of the viral influenza B neuraminidase.The neuraminidases of MDCK grown human influenza A(H3N2) viruses isolated since 1994 can demonstrate receptor binding.Synthesis of highly functionalized β-aminocyclopentanecarboxylate stereoisomers by reductive ring opening reaction of isoxazolines.Solid phase assay for comparing reactivation rates of neuraminidases of influenza wild type and resistant mutants after inhibitor removal.A new access route to functionalized cispentacins from norbornene β-amino acids.The elusive crystal structure of the neuraminidase inhibitor Tamiflu (oseltamivir phosphate): molecular details of action.Pharmacophore modeling, 3D-QSAR studies, and in-silico ADME prediction of pyrrolidine derivatives as neuraminidase inhibitors.Kinetic, Thermodynamic, and Structural Analysis of Drug Resistance Mutations in Neuraminidase from the 2009 Pandemic Influenza VirusComparison of hydrocarbon-and lactam-bridged cyclic peptides as dimerization inhibitors of Leishmania infantum trypanothione reductase
P2860
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P2860
Structural and Functional Basis of Resistance to Neuraminidase Inhibitors of Influenza B Viruses
description
2010 nî lūn-bûn
@nan
2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Structural and Functional Basi ...... ibitors of Influenza B Viruses
@ast
Structural and Functional Basi ...... ibitors of Influenza B Viruses
@en
Structural and Functional Basi ...... ibitors of Influenza B Viruses
@nl
type
label
Structural and Functional Basi ...... ibitors of Influenza B Viruses
@ast
Structural and Functional Basi ...... ibitors of Influenza B Viruses
@en
Structural and Functional Basi ...... ibitors of Influenza B Viruses
@nl
prefLabel
Structural and Functional Basi ...... ibitors of Influenza B Viruses
@ast
Structural and Functional Basi ...... ibitors of Influenza B Viruses
@en
Structural and Functional Basi ...... ibitors of Influenza B Viruses
@nl
P2093
P2860
P50
P356
P1476
Structural and functional basi ...... ibitors of influenza B viruses
@en
P2093
Lynne Waddington
Masato Tashiro
Takehiko Saito
Victor A Streltsov
P2860
P304
P356
10.1021/JM100621S
P407
P577
2010-09-01T00:00:00Z