Allosteric Modulation of Ras-GTP Is Linked to Signal Transduction through RAF Kinase
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Analysis of Binding Site Hot Spots on the Surface of Ras GTPaseLive-cell microscopy reveals small molecule inhibitor effects on MAPK pathway dynamicsA comprehensive survey of Ras mutations in cancer.Molecular Mechanism for Conformational Dynamics of Ras·GTP Elucidated from In-Situ Structural Transition in CrystalThe role of conserved waters in conformational transitions of Q61H K-ras.Structure-energy-based predictions and network modelling of RASopathy and cancer missense mutationsTyrosine phosphorylation of RAS by ABL allosterically enhances effector bindingA Novel HRAS Mutation Independently Contributes to Left Ventricular Hypertrophy in a Family with a Known MYH7 Mutation.Neutron Crystal Structure of RAS GTPase Puts in Question the Protonation State of the GTP γ-Phosphate.KRAS insertion mutations are oncogenic and exhibit distinct functional properties.Searching for the Chokehold of NRAS Mutant Melanoma.Lessons from computer simulations of Ras proteins in solution and in membraneSmall G proteins Rac1 and Ras regulate serine/threonine protein phosphatase 5 (PP5)·extracellular signal-regulated kinase (ERK) complexes involved in the feedback regulation of Raf1.Decoding RAS isoform and codon-specific signalling.Computational allosteric ligand binding site identification on Ras proteins.Targeting the KRAS variant for treatment of non-small cell lung cancer: potential therapeutic applications.The small GTPases K-Ras, N-Ras, and H-Ras have distinct biochemical properties determined by allosteric effects.Biochemical Classification of Disease-associated Mutants of RAS-like Protein Expressed in Many Tissues (RIT1).Drugging Ras GTPase: a comprehensive mechanistic and signaling structural view.ACB-PCR measurement of spontaneous and furan-induced H-ras codon 61 CAA to CTA and CAA to AAA mutation in B6C3F1 mouse liver.Molecular Dynamics Simulations and Dynamic Network Analysis Reveal the Allosteric Unbinding of Monobody to H-Ras Triggered by R135K Mutation.Mechanistic Insights into the Differential Catalysis by RheB and Its Mutants: Y35A and Y35A-D65A.
P2860
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P2860
Allosteric Modulation of Ras-GTP Is Linked to Signal Transduction through RAF Kinase
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2011 nî lūn-bûn
@nan
2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2011年の論文
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2011年論文
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2011年論文
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2011年論文
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2011年論文
@zh-mo
2011年論文
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2011年论文
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name
Allosteric Modulation of Ras-GTP Is Linked to Signal Transduction through RAF Kinase
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Allosteric Modulation of Ras-GTP Is Linked to Signal Transduction through RAF Kinase
@en
Allosteric Modulation of Ras-GTP Is Linked to Signal Transduction through RAF Kinase
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type
label
Allosteric Modulation of Ras-GTP Is Linked to Signal Transduction through RAF Kinase
@ast
Allosteric Modulation of Ras-GTP Is Linked to Signal Transduction through RAF Kinase
@en
Allosteric Modulation of Ras-GTP Is Linked to Signal Transduction through RAF Kinase
@nl
prefLabel
Allosteric Modulation of Ras-GTP Is Linked to Signal Transduction through RAF Kinase
@ast
Allosteric Modulation of Ras-GTP Is Linked to Signal Transduction through RAF Kinase
@en
Allosteric Modulation of Ras-GTP Is Linked to Signal Transduction through RAF Kinase
@nl
P2093
P2860
P3181
P356
P1476
Allosteric modulation of Ras-GTP is linked to signal transduction through RAF kinase
@en
P2093
Carla Mattos
Greg Buhrman
Murat Cirit
V S Senthil Kumar
P2860
P304
P3181
P356
10.1074/JBC.M110.193854
P407
P577
2010-11-22T00:00:00Z