Reverse type I inhibitor of Mycobacterium tuberculosis CYP125A1 - Wikidata - awgldk - TriplyDB

Reverse type I inhibitor of Mycobacterium tuberculosis CYP125A1

Reverse type I inhibitor of Mycobacterium tuberculosis CYP125A1

http://www.wikidata.org/entity/Q27666066

about

Diverse inhibitor chemotypes targeting Trypanosoma cruzi CYP51 Cholesterol ester oxidation by mycobacterial cytochrome P450.Cholesterol catabolism as a therapeutic target in Mycobacterium tuberculosis.Drug modulation of water-heme interactions in low-spin P450 complexes of CYP2C9d and CYP125A1.Discovery and Biophysical Evaluation of First Low Nanomolar Hits Targeting CYP125 of M. tuberculosis.Fragment-Based Approaches to the Development of Mycobacterium tuberculosis CYP121 Inhibitors.Mycobacterium tuberculosis cytochrome P450 enzymes: a cohort of novel TB drug targets.Cholesterol metabolism: a potential therapeutic target in Mycobacteria.Significant reduction in errors associated with nonbonded contacts in protein crystal structures: automated all-atom refinement with PrimeX.Potential drug targets in the Mycobacterium tuberculosis cytochrome P450 system.CW EPR parameters reveal cytochrome P450 ligand binding modes.

P2860

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P2860

Reverse type I inhibitor of Mycobacterium tuberculosis CYP125A1

http://www.wikidata.org/entity/Q27666066

description

2011 nî lūn-bûn

@nan

2011 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի հունվարին հրատարակված գիտական հոդված

@hy

2011年の論文

@ja

2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

name

Reverse type I inhibitor of Mycobacterium tuberculosis CYP125A1

@ast

Reverse type I inhibitor of Mycobacterium tuberculosis CYP125A1

@en

Reverse type I inhibitor of Mycobacterium tuberculosis CYP125A1

@nl

type

label

Reverse type I inhibitor of Mycobacterium tuberculosis CYP125A1

@ast

Reverse type I inhibitor of Mycobacterium tuberculosis CYP125A1

@en

Reverse type I inhibitor of Mycobacterium tuberculosis CYP125A1

@nl

prefLabel

Reverse type I inhibitor of Mycobacterium tuberculosis CYP125A1

@ast

Reverse type I inhibitor of Mycobacterium tuberculosis CYP125A1

@en

Reverse type I inhibitor of Mycobacterium tuberculosis CYP125A1

@nl

P1433

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P1476

Q27666066-0C761D32-9140-43B5-BB0B-ABC24582B0D4

P2093

Q27666066-B4839A18-00A8-44CB-9071-83C581EF2D96

Q27666066-B7313299-B5EC-4197-8E33-1010437AC75B

Q27666066-C86B046B-34E9-41DE-8216-3798E4A8500E

Q27666066-E7CBD983-5953-4604-8600-A0B431D0EB21

P2860

Q27666066-01E1C1E8-B577-41B8-B951-2A0DDF87ABCA

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P304

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P3181

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P932

Q27666066-B67FB2ED-B4CB-452D-9CAC-61EA365E1C78

P3181

P356

J.BMCL.2010.11.007

P1433

Bioorganic & Medicinal Chemistry Letters

P1476

Reverse type I inhibitor of Mycobacterium tuberculosis CYP125A1

@en

P2093

Hugues Ouellet

http://www.w3.org/2001/XMLSchema#string

Larissa M Podust

http://www.w3.org/2001/XMLSchema#string

Paul R Ortiz de Montellano

http://www.w3.org/2001/XMLSchema#string

Petrea M Kells

http://www.w3.org/2001/XMLSchema#string

P2860

Studies of a ring-cleaving dioxygenase illuminate the role of cholesterol metabolism in the pathogenesis of Mycobacterium tuberculosis

Mycobacterium tuberculosis CYP125A1, a steroid C27 monooxygenase that detoxifies intracellularly generated cholest-4-en-3-one

Mycobacterial cytochrome p450 125 (cyp125) catalyzes the terminal hydroxylation of c27 steroids

The Structure of Mycobacterium tuberculosis CYP125: molecular basis for cholesterol binding in a P450 needed for host infection

From The Cover: Automated protein crystal structure determination using ELVES

Small-Molecule Scaffolds for CYP51 Inhibitors Identified by High-Throughput Screening and Defined by X-Ray Crystallography

Mycobacterium tuberculosis CYP130: CRYSTAL STRUCTURE, BIOPHYSICAL CHARACTERIZATION, AND INTERACTIONS WITH ANTIFUNGAL AZOLE DRUGS

Trypanosoma cruzi CYP51 Inhibitor Derived from a Mycobacterium tuberculosis Screen Hit

Identification and structural basis of the reaction catalyzed by CYP121, an essential cytochrome P450 in Mycobacterium tuberculosis

Interaction of Mycobacterium tuberculosis CYP130 with Heterocyclic Arylamines

P304

332-7

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

5106228

http://www.w3.org/2001/XMLSchema#string

P356

10.1016/J.BMCL.2010.11.007

http://www.w3.org/2001/XMLSchema#string

P407

P433

1

http://www.w3.org/2001/XMLSchema#string

P478

21

http://www.w3.org/2001/XMLSchema#string

P577

2011-01-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

49637489

http://www.w3.org/2001/XMLSchema#string

P698

21109436

http://www.w3.org/2001/XMLSchema#string

P921

Aagianik kimischri

Mycobacterium tuberculosis

clinical chemistry

P932

3011832

http://www.w3.org/2001/XMLSchema#string