Crystal Structure of the 6-Hydroxymethyl-7,8-Dihydropterin Pyrophosphokinase•Dihydropteroate Synthase Bifunctional Enzyme from Francisella tularensis
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Crystal structures of Burkholderia cenocepacia dihydropteroate synthase in the apo-form and complexed with the product 7,8-dihydropteroateStructure of S. aureus HPPK and the Discovery of a New Substrate Site InhibitorExploring the chemical space around 8-mercaptoguanine as a route to new inhibitors of the folate biosynthesis enzyme HPPKCatalysis and Sulfa Drug Resistance in Dihydropteroate SynthaseThe identification, analysis and structure-based development of novel inhibitors of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinaseType II Fatty Acid Synthesis Is Essential for the Replication of Chlamydia trachomatisStructural enzymology and inhibition of the bi-functional folate pathway enzyme HPPK-DHPS from the biowarfare agent Francisella tularensisReplacing sulfa drugs with novel DHPS inhibitorsBinding Isotope Effects for para-Aminobenzoic Acid with Dihydropteroate Synthase from Staphylococcus aureus and Plasmodium falciparumMolecular determinants of sulfadoxine-pyrimethamine resistance in Plasmodium falciparum in Nigeria and the regional emergence of dhps 431VUtility of the Biosynthetic Folate Pathway for Targets in Antimicrobial Discovery.8-Mercaptoguanine Derivatives as Inhibitors of Dihydropteroate Synthase.Insights into the drug resistance induced by the BaDHPS mutations: molecular dynamic simulations and MM/GBSA studies.Structure of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase-dihydropteroate synthase from Plasmodium vivax sheds light on drug resistance
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P2860
Crystal Structure of the 6-Hydroxymethyl-7,8-Dihydropterin Pyrophosphokinase•Dihydropteroate Synthase Bifunctional Enzyme from Francisella tularensis
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2010 nî lūn-bûn
@nan
2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Crystal Structure of the 6-Hyd ...... me from Francisella tularensis
@ast
Crystal Structure of the 6-Hyd ...... me from Francisella tularensis
@en
Crystal Structure of the 6-Hyd ...... me from Francisella tularensis
@nl
type
label
Crystal Structure of the 6-Hyd ...... me from Francisella tularensis
@ast
Crystal Structure of the 6-Hyd ...... me from Francisella tularensis
@en
Crystal Structure of the 6-Hyd ...... me from Francisella tularensis
@nl
prefLabel
Crystal Structure of the 6-Hyd ...... me from Francisella tularensis
@ast
Crystal Structure of the 6-Hyd ...... me from Francisella tularensis
@en
Crystal Structure of the 6-Hyd ...... me from Francisella tularensis
@nl
P2093
P2860
P1433
P1476
Crystal Structure of the 6-Hyd ...... me from Francisella tularensis
@en
P2093
Amanda Nourse
Charles W Pemble
Smriti Mehra
Stephen W White
Zhenmei Li
P2860
P304
P356
10.1371/JOURNAL.PONE.0014165
P407
P577
2010-11-30T00:00:00Z