Crystal structure of the amyloid-β p3 fragment provides a model for oligomer formation in Alzheimer's disease
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Alzheimer's disease--a panorama glimpseDimer formation enhances structural differences between amyloid β-protein (1-40) and (1-42): an explicit-solvent molecular dynamics studyAtomic View of a Toxic Amyloid Small OligomerX-ray Crystallographic Structures of Trimers and Higher-Order Oligomeric Assemblies of a Peptide Derived from Aβ 17–36Structural studies of the tethered N-terminus of the Alzheimer's disease amyloid-β peptideCrystal structure reveals conservation of amyloid-β conformation recognized by 3D6 following humanization to bapineuzumabA Fibril-Like Assembly of Oligomers of a Peptide Derived from β-AmyloidAnalysis of conformational variation in macromolecular structural modelsAll-d-Enantiomer of β-Amyloid Peptide Forms Ion Channels in Lipid Bilayers.Antiparallel triple-strand architecture for prefibrillar Aβ42 oligomersThe conformational stability of nonfibrillar amyloid-β peptide oligomers critically depends on the C-terminal peptide length.Modeling amyloid-beta as homogeneous dodecamers and in complex with cellular prion protein.Structural basis for Aβ1–42 toxicity inhibition by Aβ C-terminal fragments: discrete molecular dynamics study.Interaction of amyloid inhibitor proteins with amyloid beta peptides: insight from molecular dynamics simulationsIntra-membrane oligomerization and extra-membrane oligomerization of amyloid-β peptide are competing processes as a result of distinct patterns of motif interplay.Two distinct β-sheet structures in Italian-mutant amyloid-beta fibrils: a potential link to different clinical phenotypes.IBC's 22nd Annual Antibody Engineering and 9th Annual Antibody Therapeutics International Conferences and the 2011 Annual Meeting of The Antibody Society, December 5-8, 2011, San Diego, CA.Structural insights into Aβ42 oligomers using site-directed spin labelingComputational approaches to understanding protein aggregation in neurodegeneration.Microsecond molecular dynamics simulation of Aβ42 and identification of a novel dual inhibitor of Aβ42 aggregation and BACE1 activity.Polymorphism of oligomers of a peptide from β-amyloid.Biotechnological applications of recombinant single-domain antibody fragments.The role of metallobiology and amyloid-β peptides in Alzheimer's disease.Biochemistry of amyloid β-protein and amyloid deposits in Alzheimer disease.Misfolding of amyloidogenic proteins and their interactions with membranes.Structural insights and biomedical potential of IgNAR scaffolds from sharks.Single-domain antibodies for biomedical applications.An Account of Amyloid Oligomers: Facts and Figures Obtained from Experiments and Simulations.Disease-modifying anti-Alzheimer's drugs: inhibitors of human cholinesterases interfering with β-amyloid aggregation.Energetic contributions of residues to the formation of early amyloid-β oligomers.Modulation of amyloid-β 1-42 structure and toxicity by proline-rich whey peptides.Allosteric inhibition of Aurora-A kinase by a synthetic vNAR domain.Insights into the disparate action of osmolytes and macromolecular crowders on amyloid formation.A structure-toxicity study of Aß42 reveals a new anti-parallel aggregation pathway.Single Domain Antibodies as New Biomarker Detectors.Novel, Anti-hTNF-α Variable New Antigen Receptor Formats with Enhanced Neutralizing Potency and Multifunctionality, Generated for Therapeutic Development.Generation of Semi-Synthetic Shark IgNAR Single-Domain Antibody Libraries.Is the novel amyloid-β tetramer fold a stable conformation?
P2860
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P2860
Crystal structure of the amyloid-β p3 fragment provides a model for oligomer formation in Alzheimer's disease
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2011 nî lūn-bûn
@nan
2011 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Crystal structure of the amylo ...... rmation in Alzheimer's disease
@ast
Crystal structure of the amylo ...... rmation in Alzheimer's disease
@en
Crystal structure of the amylo ...... rmation in Alzheimer's disease
@nl
type
label
Crystal structure of the amylo ...... rmation in Alzheimer's disease
@ast
Crystal structure of the amylo ...... rmation in Alzheimer's disease
@en
Crystal structure of the amylo ...... rmation in Alzheimer's disease
@nl
prefLabel
Crystal structure of the amylo ...... rmation in Alzheimer's disease
@ast
Crystal structure of the amylo ...... rmation in Alzheimer's disease
@en
Crystal structure of the amylo ...... rmation in Alzheimer's disease
@nl
P2093
P3181
P1476
Crystal structure of the amylo ...... rmation in Alzheimer's disease
@en
P2093
Colin L Masters
Joseph N Varghese
Stewart D Nuttall
Victor A Streltsov
P304
P3181
P356
10.1523/JNEUROSCI.4259-10.2011
P407
P577
2011-01-01T00:00:00Z