Crystal structure reveals conservation of amyloid-β conformation recognized by 3D6 following humanization to bapineuzumab
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N-Terminal Extensions Retard Aβ42 Fibril Formation but Allow Cross-Seeding and Coaggregation with Aβ42Secreted amyloid β-proteins in a cell culture model include N-terminally extended peptides that impair synaptic plasticityMolecular basis for mid-region amyloid-β capture by leading Alzheimer's disease immunotherapies.A highly sensitive novel immunoassay specifically detects low levels of soluble Aβ oligomers in human cerebrospinal fluid.Conformational selection in amyloid-based immunotherapy: Survey of crystal structures of antibody-amyloid complexes.An Introduction to B-Cell Epitope Mapping and In Silico Epitope Prediction.A coiled conformation of amyloid-β recognized by antibody C706.Structural and functional analyses of pyroglutamate-amyloid-β-specific antibodies as a basis for Alzheimer immunotherapy.Mechanisms of recognition of amyloid-β (Aβ) monomer, oligomer, and fibril by homologous antibodies.Anti-Aβ antibody target engagement: a response to Siemers et al.Structural and kinetic basis for the selectivity of aducanumab for aggregated forms of amyloid-β.Abeta targets of the biosimilar antibodies of Bapineuzumab, Crenezumab, Solanezumab in comparison to an antibody against N‑truncated Abeta in sporadic Alzheimer disease cases and mouse models.Antibody Engineering for Optimized Immunotherapy in Alzheimer's Disease.
P2860
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P2860
Crystal structure reveals conservation of amyloid-β conformation recognized by 3D6 following humanization to bapineuzumab
description
2014 nî lūn-bûn
@nan
2014 թուականին հրատարակուած գիտական յօդուած
@hyw
2014 թվականին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Crystal structure reveals cons ...... g humanization to bapineuzumab
@ast
Crystal structure reveals cons ...... g humanization to bapineuzumab
@en
Crystal structure reveals cons ...... g humanization to bapineuzumab
@nl
type
label
Crystal structure reveals cons ...... g humanization to bapineuzumab
@ast
Crystal structure reveals cons ...... g humanization to bapineuzumab
@en
Crystal structure reveals cons ...... g humanization to bapineuzumab
@nl
prefLabel
Crystal structure reveals cons ...... g humanization to bapineuzumab
@ast
Crystal structure reveals cons ...... g humanization to bapineuzumab
@en
Crystal structure reveals cons ...... g humanization to bapineuzumab
@nl
P2093
P2860
P356
P1476
Crystal structure reveals cons ...... g humanization to bapineuzumab
@en
P2093
Amita Goel
Angela Widom
Dale Schenk
Geertruida M Veldman
Guriqbal S Basi
Hadar Feinberg
José W Saldanha
Linnea Diep
William I Weis
P2860
P2888
P356
10.1186/ALZRT261
P407
P577
2014-01-01T00:00:00Z
P5875
P6179
1022392029