Allosteric control of ligand-binding affinity using engineered conformation-specific effector proteins
about
Evidence for an allosteric mechanism of substrate release from membrane-transporter accessory binding proteinsStructure of active β-arrestin-1 bound to a G-protein-coupled receptor phosphopeptideAn allosteric switch for pro-HGF/Met signaling using zymogen activator peptidesNuclear pores. Architecture of the nuclear pore complex coat.Crystal structures of MBP fusion proteinsDiscovery of an auto-regulation mechanism for the maltose ABC transporter MalFGK2Targeted rescue of cancer-associated IDH1 mutant activity using an engineered synthetic antibody.Structural mechanism of voltage-dependent gating in an isolated voltage-sensing domainSynthetic Fab fragments that bind the HIV-1 gp41 heptad repeat regions.Generating conformation-specific synthetic antibodies to trap proteins in selected functional statesApplications for an engineered Protein-G variant with a pH controllable affinity to antibody fragments.Engineering synthetic antibody binders for allosteric inhibition of prolactin receptor signaling.A New Versatile Immobilization Tag Based on the Ultra High Affinity and Reversibility of the Calmodulin-Calmodulin Binding Peptide Interaction.Identification of a tetratricopeptide repeat-like domain in the nicastrin subunit of γ-secretase using synthetic antibodiesA YidC-like Protein in the Archaeal Plasma Membrane.Generating Conformation and Complex-Specific Synthetic Antibodies.Competitive interactions of ligands and macromolecular crowders with maltose binding protein.Conformational Change of a Tryptophan Residue in BtuF Facilitates Binding and Transport of Cobinamide by the Vitamin B12 Transporter BtuCD-F.Conformational Chaperones for Structural Studies of Membrane Proteins Using Antibody Phage Display with NanodiscsProtein engineering: a new frontier for biological therapeutics.Dynamical persistence of active sites identified in maltose-binding protein.Protein targeting. Structure of the Get3 targeting factor in complex with its membrane protein cargo.Inhibition of insulin receptor function by a human, allosteric monoclonal antibody: a potential new approach for the treatment of hyperinsulinemic hypoglycemia.Using persistent homology and dynamical distances to analyze protein binding.Human antibody-based chemically induced dimerizers for cell therapeutic applications.Locking the Elbow: Improved Antibody Fab Fragments as Chaperones for Structure Determination.Yeast surface display platform for rapid discovery of conformationally selective nanobodies.Engineered synthetic antibodies as probes to quantify the energetic contributions of ligand binding to conformational changes in proteins.Synthetic single domain antibodies for the conformational trapping of membrane proteins.
P2860
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P2860
Allosteric control of ligand-binding affinity using engineered conformation-specific effector proteins
description
2011 nî lūn-bûn
@nan
2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Allosteric control of ligand-b ...... ion-specific effector proteins
@ast
Allosteric control of ligand-b ...... ion-specific effector proteins
@en
Allosteric control of ligand-b ...... ion-specific effector proteins
@nl
type
label
Allosteric control of ligand-b ...... ion-specific effector proteins
@ast
Allosteric control of ligand-b ...... ion-specific effector proteins
@en
Allosteric control of ligand-b ...... ion-specific effector proteins
@nl
prefLabel
Allosteric control of ligand-b ...... ion-specific effector proteins
@ast
Allosteric control of ligand-b ...... ion-specific effector proteins
@en
Allosteric control of ligand-b ...... ion-specific effector proteins
@nl
P2093
P2860
P356
P1476
Allosteric control of ligand-b ...... ion-specific effector proteins
@en
P2093
Andrew Sandstrom
Anthony A Kossiakoff
Erica M Duguid
John H Heithaus
Marcin Paduch
Shahir S Rizk
P2860
P2888
P304
P356
10.1038/NSMB.2002
P577
2011-04-01T00:00:00Z
P5875
P6179
1042400570