A Small-Molecule Probe Induces a Conformation in HIV TAR RNA Capable of Binding Drug-Like Fragments
about
Structure based approaches for targeting non-coding RNAs with small moleculesUsing a Fragment-Based Approach To Target Protein-Protein InteractionsEfficient in silico exploration of RNA interhelical conformations using Euler angles and WExploreSaturation transfer difference NMR for fragment screening.Coarse grained models reveal essential contributions of topological constraints to the conformational free energy of RNA bulges.Examining the relationship between RNA function and motion using nuclear magnetic resonance.Strategies to Block HIV Transcription: Focus on Small Molecule Tat Inhibitors.Targeting HIV transcription: the quest for a functional cure.The Emerging Role of RNA as a Therapeutic Target for Small Molecules.Distinct conformational transition patterns of noncoding 7SK snRNA and HIV TAR RNAs upon Tat bindingImproving combination antiretroviral therapy by targeting HIV-1 gene transcription.Molecular dynamics simulations identify time scale of conformational changes responsible for conformational selection in molecular recognition of HIV-1 transactivation responsive RNA.A novel paramagnetic relaxation enhancement tag for nucleic acids: a tool to study structure and dynamics of RNA.A method of determining RNA conformational ensembles using structure-based calculations of residual dipolar couplings.Amiloride as a new RNA-binding scaffold with activity against HIV-1 TAR.
P2860
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P2860
A Small-Molecule Probe Induces a Conformation in HIV TAR RNA Capable of Binding Drug-Like Fragments
description
2011 nî lūn-bûn
@nan
2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
A Small-Molecule Probe Induces ...... of Binding Drug-Like Fragments
@ast
A Small-Molecule Probe Induces ...... of Binding Drug-Like Fragments
@en
A Small-Molecule Probe Induces ...... of Binding Drug-Like Fragments
@nl
type
label
A Small-Molecule Probe Induces ...... of Binding Drug-Like Fragments
@ast
A Small-Molecule Probe Induces ...... of Binding Drug-Like Fragments
@en
A Small-Molecule Probe Induces ...... of Binding Drug-Like Fragments
@nl
prefLabel
A Small-Molecule Probe Induces ...... of Binding Drug-Like Fragments
@ast
A Small-Molecule Probe Induces ...... of Binding Drug-Like Fragments
@en
A Small-Molecule Probe Induces ...... of Binding Drug-Like Fragments
@nl
P2093
P2860
P1476
A Small-Molecule Probe Induces ...... of Binding Drug-Like Fragments
@en
P2093
Amy Davidson
Carmen Lau
Darren W Begley
P2860
P304
P356
10.1016/J.JMB.2011.03.039
P407
P577
2011-07-29T00:00:00Z