Type II p21-activated kinases (PAKs) are regulated by an autoinhibitory pseudosubstrate
about
Group II p21-activated kinases as therapeutic targets in gastrointestinal cancerThe role of p21-activated kinases in hepatocellular carcinoma metastasisPAK4 promotes kinase-independent stabilization of RhoU to modulate cell adhesionAn in cellulo-derived structure of PAK4 in complex with its inhibitor Inka1Substrate and Inhibitor Specificity of the Type II p21-Activated Kinase, PAK6Identification of a Major Determinant for Serine-Threonine Kinase Phosphoacceptor SpecificitySignaling, Regulation, and Specificity of the Type II p21-activated KinasesLeucine-rich repeat kinase 2 interacts with p21-activated kinase 6 to control neurite complexity in mammalian brainPAK6 targets to cell-cell adhesions through its N-terminus in a Cdc42-dependent manner to drive epithelial colony escapePAK signalling during the development and progression of cancerPAK4 interacts with p85 alpha: implications for pancreatic cancer cell migrationActivated-PAK4 predicts worse prognosis in breast cancer and promotes tumorigenesis through activation of PI3K/AKT signaling.The Cdc42 Effector Kinase PAK4 Localizes to Cell-Cell Junctions and Contributes to Establishing Cell Polarity.PAK4 Methylation by SETD6 Promotes the Activation of the Wnt/β-Catenin Pathway.Structural Basis for Noncanonical Substrate Recognition of Cofilin/ADF Proteins by LIM KinasesRegulation of Janus kinases by SOCS proteins.A novel phosphorylation site at Ser130 adjacent to the pseudosubstrate domain contributes to the activation of protein kinase C-δ.P21 activated kinases: structure, regulation, and functions.Structure, biochemistry, and biology of PAK kinases.Functional cross-talk between Cdc42 and two downstream targets, Par6B and PAK4.PAK6 Phosphorylates 14-3-3γ to Regulate Steady State Phosphorylation of LRRK2.CDC42 binds PAK4 via an extended GTPase-effector interface.PAK4 crystal structures suggest unusual kinase conformational movements.Melanoma-associated mutants within the serine-rich domain of PAK5 direct kinase activity to mitogenic pathways.p21-activated kinase signalling in pancreatic cancer: New insights into tumour biology and immune modulation
P2860
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P2860
Type II p21-activated kinases (PAKs) are regulated by an autoinhibitory pseudosubstrate
description
2012 nî lūn-bûn
@nan
2012 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Type II p21-activated kinases (PAKs) are regulated by an autoinhibitory pseudosubstrate
@ast
Type II p21-activated kinases (PAKs) are regulated by an autoinhibitory pseudosubstrate
@en
Type II p21-activated kinases (PAKs) are regulated by an autoinhibitory pseudosubstrate
@nl
type
label
Type II p21-activated kinases (PAKs) are regulated by an autoinhibitory pseudosubstrate
@ast
Type II p21-activated kinases (PAKs) are regulated by an autoinhibitory pseudosubstrate
@en
Type II p21-activated kinases (PAKs) are regulated by an autoinhibitory pseudosubstrate
@nl
prefLabel
Type II p21-activated kinases (PAKs) are regulated by an autoinhibitory pseudosubstrate
@ast
Type II p21-activated kinases (PAKs) are regulated by an autoinhibitory pseudosubstrate
@en
Type II p21-activated kinases (PAKs) are regulated by an autoinhibitory pseudosubstrate
@nl
P2093
P2860
P356
P1476
Type II p21-activated kinases (PAKs) are regulated by an autoinhibitory pseudosubstrate
@en
P2093
Benjamin E Turk
Byung Hak Ha
Catherine Chen
Hua Jane Lou
Matthew J Davis
Michael Krauthammer
Rong Zhang
Ruth Halaban
Titus J Boggon
P2860
P304
P356
10.1073/PNAS.1214447109
P407
P577
2012-10-02T00:00:00Z