Structural basis for nematode eIF4E binding an m2,2,7G-Cap and its implications for translation initiation - Wikidata - awgldk - TriplyDB

Structural basis for nematode eIF4E binding an m2,2,7G-Cap and its implications for translation initiation

Structural basis for nematode eIF4E binding an m2,2,7G-Cap and its implications for translation initiation

http://www.wikidata.org/entity/Q27674684

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Eukaryotic translation initiation is controlled by cooperativity effects within ternary complexes of 4E-BP1, eIF4E, and the mRNA 5' cap Crystal structure of a minimal eIF4E-Cup complex reveals a general mechanism of eIF4E regulation in translational repression eIF4E3 acts as a tumor suppressor by utilizing an atypical mode of methyl-7-guanosine cap recognition Structural insights into the substrate-binding mechanism for a novel chitosanase Distinct features of cap binding by eIF4E1b proteins 5'-Terminal chemical capping of spliced leader RNAs.Synthesis of N²-modified 7-methylguanosine 5'-monophosphates as nematode translation inhibitors Synthesis of ¹³C- and ¹⁴C-labeled dinucleotide mRNA cap analogues for structural and biochemical studies The oncogene eIF4E: using biochemical insights to target cancer.Characterization of the Raptor/4E-BP1 interaction by chemical cross-linking coupled with mass spectrometry analysis.Molecular cloning and characterization of SL3: a stem cell-specific SL RNA from the planarian Schmidtea mediterranea.The eukaryotic translation initiation factor eIF4E wears a "cap" for many occasions.Conformational changes induced in the eukaryotic translation initiation factor eIF4E by a clinically relevant inhibitor, ribavirin triphosphate.

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Structural basis for nematode eIF4E binding an m2,2,7G-Cap and its implications for translation initiation

http://www.wikidata.org/entity/Q27674684

description

2011 nî lūn-bûn

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2011 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

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2011 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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Structural basis for nematode ...... ons for translation initiation

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Structural basis for nematode ...... ons for translation initiation

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Nucleic Acids Research

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Adam Wallace

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David N M Jones

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Janusz Stepinski

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Jeffrey Kieft

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Karolina Piecyk

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Laura Dickson

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Marzena Jankowska-Anyszka

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Richard E Davis

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Rui Zhao

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Ryszard Stolarski

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P2860

Neglected infections of poverty in the United States of America

Structures of the human eIF4E homologous protein, h4EHP, in its m7GTP-bound and unliganded forms

Structural basis for m3G-cap-mediated nuclear import of spliceosomal UsnRNPs by snurportin1

Cap-dependent translation initiation in eukaryotes is regulated by a molecular mimic of eIF4G

Crystal structures of 7-methylguanosine 5'-triphosphate (m(7)GTP)- and P(1)-7-methylguanosine-P(3)-adenosine-5',5'-triphosphate (m(7)GpppA)-bound human full-length eukaryotic initiation factor 4E: biological importance of the C-terminal flexible reg

Biophysical studies of eIF4E cap-binding protein: recognition of mRNA 5' cap structure and synthetic fragments of eIF4G and 4E-BP1 proteins

Ribosome loading onto the mRNA cap is driven by conformational coupling between eIF4G and eIF4E

The Structure of Eukaryotic Translation Initiation Factor-4E from Wheat Reveals a Novel Disulfide Bond

Crystallographic and mass spectrometric characterisation of eIF4E with N7-alkylated cap derivatives

Structural Insights into Parasite eIF4E Binding Specificity for m7G and m2,2,7G mRNA Caps

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8820-32

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scholarly article

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4154908

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10.1093/NAR/GKR650

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20

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39

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Anna Niedźwiecka

Edward Darżynkiewicz

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51686868

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21965542

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3203607

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