Functional and structural analysis of the human SLO3 pH- and voltage-gated K+ channel
about
SLO3 auxiliary subunit LRRC52 controls gating of sperm KSPER currents and is critical for normal fertilityMembrane hyperpolarization during human sperm capacitationRecent progress on the structure and function of the TrkH/KtrB ion channelIon permeabilities in mouse sperm reveal an external trigger for SLO3-dependent hyperpolarization.Identification of the Intracellular Na+ Sensor in Slo2.1 Potassium Channels.Cryo-electron microscopy structure of the Slo2.2 Na(+)-activated K(+) channel.Slo1 is the principal potassium channel of human spermatozoa.The Ca2+-activated K+ current of human sperm is mediated by Slo3.Functional regulation of BK potassium channels by γ1 auxiliary subunits.Intracellular calcium-dependent regulation of the sperm-specific calcium-activated potassium channel, hSlo3, by the BKCa activator LDD175.Patch clamp studies of human sperm under physiological ionic conditions reveal three functionally and pharmacologically distinct cation channels.Potassium channels: structures, diseases, and modulators.T-type Ca2+ channels in spermatogenic cells and sperm.Understanding the conformational motions of RCK gating rings.International Union of Basic and Clinical Pharmacology. C. Nomenclature and Properties of Calcium-Activated and Sodium-Activated Potassium Channels.A genetic variant of the sperm-specific SLO3 K+ channel has altered pH and Ca2+ sensitivities.The anti-inflammatory drug celecoxib inhibits T-type Ca2+ currents in spermatogenic cells yet it elicits the acrosome reaction in mature sperm.
P2860
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P2860
Functional and structural analysis of the human SLO3 pH- and voltage-gated K+ channel
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2012 nî lūn-bûn
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2012 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Functional and structural analysis of the human SLO3 pH- and voltage-gated K+ channel
@ast
Functional and structural analysis of the human SLO3 pH- and voltage-gated K+ channel
@en
Functional and structural analysis of the human SLO3 pH- and voltage-gated K+ channel
@nl
type
label
Functional and structural analysis of the human SLO3 pH- and voltage-gated K+ channel
@ast
Functional and structural analysis of the human SLO3 pH- and voltage-gated K+ channel
@en
Functional and structural analysis of the human SLO3 pH- and voltage-gated K+ channel
@nl
prefLabel
Functional and structural analysis of the human SLO3 pH- and voltage-gated K+ channel
@ast
Functional and structural analysis of the human SLO3 pH- and voltage-gated K+ channel
@en
Functional and structural analysis of the human SLO3 pH- and voltage-gated K+ channel
@nl
P2093
P2860
P356
P1476
Functional and structural analysis of the human SLO3 pH- and voltage-gated K+ channel
@en
P2093
Roderick Mackinnon
Yichun Hsiung
P2860
P304
19274-19279
P356
10.1073/PNAS.1215078109
P407
P577
2012-11-05T00:00:00Z