The Ca2+-activated K+ current of human sperm is mediated by Slo3.
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Regulation and roles of Ca2+ stores in human spermSLO3 auxiliary subunit LRRC52 controls gating of sperm KSPER currents and is critical for normal fertilityIntracellular pH in sperm physiology.SLO3 K+ channels control calcium entry through CATSPER channels in sperm.The CatSper channel controls chemosensation in sea urchin spermMechanism of inhibition of mouse Slo3 (KCa 5.1) potassium channels by quinine, quinidine and bariumSpecific loss of CatSper function is sufficient to compromise fertilizing capacity of human spermatozoa.A K(+)-selective CNG channel orchestrates Ca(2+) signalling in zebrafish sperm.Premammalian origin of the sperm-specific Slo3 channel.Intracellular calcium-dependent regulation of the sperm-specific calcium-activated potassium channel, hSlo3, by the BKCa activator LDD175.Importance of β-defensins in sperm function.Mechanistic insight into the heme-independent interplay between iron and carbon monoxide in CFTR and Slo1 BKCa channels.Sperm Capacitation and Acrosome Reaction in Mammalian Sperm.Sperm Sensory Signaling.International Union of Basic and Clinical Pharmacology. C. Nomenclature and Properties of Calcium-Activated and Sodium-Activated Potassium Channels.Contraception: Search for an Ideal Unisex Mechanism by Targeting Ion Channels.Depolarization of sperm membrane potential is a common feature of men with subfertility and is associated with low fertilization rate at IVF.Post-translational cleavage of Hv1 in human sperm tunes pH- and voltage-dependent gating.A genetic variant of the sperm-specific SLO3 K+ channel has altered pH and Ca2+ sensitivities.CFTR/ENaC dependent regulation of membrane potential during human sperm capacitation is initiated by bicarbonate uptake through NBC.TRPV4 is the temperature-sensitive ion channel of human sperm
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P2860
The Ca2+-activated K+ current of human sperm is mediated by Slo3.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 26 March 2014
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
The Ca2+-activated K+ current of human sperm is mediated by Slo3.
@en
The Ca2+-activated K+ current of human sperm is mediated by Slo3.
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type
label
The Ca2+-activated K+ current of human sperm is mediated by Slo3.
@en
The Ca2+-activated K+ current of human sperm is mediated by Slo3.
@nl
prefLabel
The Ca2+-activated K+ current of human sperm is mediated by Slo3.
@en
The Ca2+-activated K+ current of human sperm is mediated by Slo3.
@nl
P2093
P2860
P356
P1433
P1476
The Ca2+-activated K+ current of human sperm is mediated by Slo3
@en
P2093
Astrid Müller
Christian Trötschel
Christoph Brenker
Fabio Andres Echeverry
Timo Strünker
U Benjamin Kaupp
Wolfgang Bönigk
Xiao-Ming Xia
P2860
P304
P356
10.7554/ELIFE.01438
P407
P577
2014-03-26T00:00:00Z