Structural Mechanisms of Allostery and Autoinhibition in JNK Family Kinases
about
JNK Signaling: Regulation and Functions Based on Complex Protein-Protein PartnershipsLigand-binding dynamics rewire cellular signaling via estrogen receptor-αCo-conserved MAPK features couple D-domain docking groove to distal allosteric sites via the C-terminal flanking tailAllosteric Autoinhibition Pathway in Transcription Factor ERG: Dynamics Network and Mutant Experimental Evaluations.Structure and dynamics of the MKK7-JNK signaling complexA small molecule bidentate-binding dual inhibitor probe of the LRRK2 and JNK kinases.The crystal structure of JNK from Drosophila melanogaster reveals an evolutionarily conserved topology with that of mammalian JNK proteinsTwo hydrophobic residues can determine the specificity of mitogen-activated protein kinase docking interactions.Molecular basis of MAP kinase regulation.Selective targeting of MAPK family kinases JNK over p38 by rationally designed peptides as potential therapeutics for neurological disorders and epilepsy.Systematic discovery of linear binding motifs targeting an ancient protein interaction surface on MAP kinases.De Novo Design and Synthesis of a γ-Turn Peptidomimetic Scaffold and Its Application as JNK3 Allosteric Ligand.New insights into the structural dynamics of the kinase JNK3.Structural determinants of Rab11 activation by the guanine nucleotide exchange factor SH3BP5
P2860
Q26741279-94D8B283-4F25-458A-8C1B-F2D0C47FE721Q27677013-440D6767-FD3D-497D-9974-4231D3093E13Q28544906-6FC1298D-95E9-49DF-928B-7F5D340676DAQ30401225-3D566216-55E1-4BCA-8490-6E81A2255DEDQ34465579-97C6D85F-823E-4E60-B0F2-B5ED53878905Q34764609-274BE457-3E19-464F-A00F-253A523E84D6Q35777940-A17BD66A-0728-4939-BC7B-699C357383DEQ36283723-B1EF8E1D-7612-4A21-9F2C-AEFBCCF9847BQ38151621-BA53B6BA-7EB1-45A0-B22A-9609CA54231DQ39708917-742394C4-3BC7-4BDA-8EE2-C6F705F3B6BFQ42276390-443E0DAC-B3D9-4C31-BD91-CB05C2BEB735Q54288404-4A7DD5FD-944B-4567-89A4-74DDC7DAC420Q55396132-3BE44DBF-CBAF-4AE1-BA96-028E923E666FQ58528267-0BDC89F1-F8B3-4FAC-9F36-4213B37780C5
P2860
Structural Mechanisms of Allostery and Autoinhibition in JNK Family Kinases
description
2012 nî lūn-bûn
@nan
2012 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Structural Mechanisms of Allostery and Autoinhibition in JNK Family Kinases
@ast
Structural Mechanisms of Allostery and Autoinhibition in JNK Family Kinases
@en
Structural Mechanisms of Allostery and Autoinhibition in JNK Family Kinases
@nl
type
label
Structural Mechanisms of Allostery and Autoinhibition in JNK Family Kinases
@ast
Structural Mechanisms of Allostery and Autoinhibition in JNK Family Kinases
@en
Structural Mechanisms of Allostery and Autoinhibition in JNK Family Kinases
@nl
prefLabel
Structural Mechanisms of Allostery and Autoinhibition in JNK Family Kinases
@ast
Structural Mechanisms of Allostery and Autoinhibition in JNK Family Kinases
@en
Structural Mechanisms of Allostery and Autoinhibition in JNK Family Kinases
@nl
P2093
P2860
P1433
P1476
Structural mechanisms of allostery and autoinhibition in JNK family kinases
@en
P2093
John D Laughlin
Kendall W Nettles
Lisa Cherry
Mariana Figuera-Losada
Philip V LoGrasso
P2860
P304
P356
10.1016/J.STR.2012.09.021
P577
2012-11-08T00:00:00Z