Structural insights into the autoactivation mechanism of p21-activated protein kinase
about
Type II p21-activated kinases (PAKs) are regulated by an autoinhibitory pseudosubstrateIRAK4 dimerization and trans-autophosphorylation are induced by Myddosome assemblyMolecular pathways: targeting p21-activated kinase 1 signaling in cancer--opportunities, challenges, and limitationsIdentifying three-dimensional structures of autophosphorylation complexes in crystals of protein kinases3D structure analysis of PAKs: A clue to the rational design for affinity reagents and blockers.P21-activated kinase in inflammatory and cardiovascular disease.Mutations in FLS2 Ser-938 dissect signaling activation in FLS2-mediated Arabidopsis immunity.Structural assembly of the signaling competent ERK2-RSK1 heterodimeric protein kinase complex.The p21-activated kinase PAK3 forms heterodimers with PAK1 in brain implementing trans-regulation of PAK3 activity.Structures of the inactive and active states of RIP2 kinase inform on the mechanism of activation.Unique catalytic activities and scaffolding of p21 activated kinase-1 in cardiovascular signalingMyosin 3A kinase activity is regulated by phosphorylation of the kinase domain activation loop.Thymoquinone-induced conformational changes of PAK1 interrupt prosurvival MEK-ERK signaling in colorectal cancer.Autophosphorylation Affects Substrate-Binding Affinity of Tobacco Ca2+-Dependent Protein Kinase1.
P2860
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P2860
Structural insights into the autoactivation mechanism of p21-activated protein kinase
description
2011 nî lūn-bûn
@nan
2011 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Structural insights into the autoactivation mechanism of p21-activated protein kinase
@ast
Structural insights into the autoactivation mechanism of p21-activated protein kinase
@en
Structural insights into the autoactivation mechanism of p21-activated protein kinase
@nl
type
label
Structural insights into the autoactivation mechanism of p21-activated protein kinase
@ast
Structural insights into the autoactivation mechanism of p21-activated protein kinase
@en
Structural insights into the autoactivation mechanism of p21-activated protein kinase
@nl
prefLabel
Structural insights into the autoactivation mechanism of p21-activated protein kinase
@ast
Structural insights into the autoactivation mechanism of p21-activated protein kinase
@en
Structural insights into the autoactivation mechanism of p21-activated protein kinase
@nl
P2093
P1433
P1476
Structural insights into the autoactivation mechanism of p21-activated protein kinase
@en
P2093
Jia-Wei Wu
Zhi-Xin Wang
P304
P356
10.1016/J.STR.2011.10.013
P577
2011-12-07T00:00:00Z