Binary complex crystal structure of DNA polymerase reveals multiple conformations of the templating 8-oxoguanine lesion
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Structures of dNTP Intermediate States during DNA Polymerase Active Site AssemblyDNA polymerase minor groove interactions modulate mutagenic bypass of a templating 8-oxoguanine lesionStructural Basis for Promutagenicity of 8-Halogenated GuanineCrystal Structure of DNA Polymerase β with DNA Containing the Base Lesion Spiroiminodihydantoin in a Templating PositionMetal-Dependent Conformational Activation Explains Highly Promutagenic Replication across O6-Methylguanine by Human DNA Polymerase βA fidelity mechanism in DNA polymerase lambda promotes error-free bypass of 8-oxo-dGStructures of DNA Polymerase Mispaired DNA Termini Transitioning to Pre-catalytic Complexes Support an Induced-Fit Fidelity MechanismOxidant and environmental toxicant-induced effects compromise DNA ligation during base excision DNA repairStructure and mechanism of DNA polymerase βA switch between DNA polymerases δ and λ promotes error-free bypass of 8-oxo-G lesionsCapturing a mammalian DNA polymerase extending from an oxidized nucleotide.Is FapyG mutagenic?: Evidence from the DFT study.Viewing Human DNA Polymerase β Faithfully and Unfaithfully Bypass an Oxidative Lesion by Time-Dependent CrystallographyIntrinsic mutagenic properties of 5-chlorocytosine: A mechanistic connection between chronic inflammation and cancerReprint of "Oxidant and environmental toxicant-induced effects compromise DNA ligation during base excision DNA repair".Klenow Fragment Discriminates against the Incorporation of the Hyperoxidized dGTP Lesion Spiroiminodihydantoin into DNA.Insertion of oxidized nucleotide triggers rapid DNA polymerase openingHow DNA polymerase X preferentially accommodates incoming dATP opposite 8-oxoguanine on the template.Oxidized nucleotide insertion by pol β confounds ligation during base excision repair.Transition state in DNA polymerase β catalysis: rate-limiting chemistry altered by base-pair configuration.Translesion DNA synthesis and mutagenesis in eukaryotesImpact of ribonucleotide incorporation by DNA polymerases β and λ on oxidative base excision repair.hOGG1-Cys326 variant cells are hypersensitive to DNA repair inhibition by nitric oxide.Base excision repair of oxidative DNA damage: from mechanism to disease.Close encounters: Moving along bumps, breaks, and bubbles on expanded trinucleotide tracts.Formation and Repair of Mismatches Containing Ribonucleotides and Oxidized Bases at Repeated DNA SequencesInsights into the effect of minor groove interactions and metal cofactors on mutagenic replication by human DNA polymerase β.Effects of Matrix Stiffness on the Morphology, Adhesion, Proliferation and Osteogenic Differentiation of Mesenchymal Stem Cells.Conformational stabilities of iminoallantoin and its base pairs in DNA: implications for mutagenicity.Structural and Kinetic Studies of the Effect of Guanine N7 Alkylation and Metal Cofactors on DNA Replication
P2860
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P2860
Binary complex crystal structure of DNA polymerase reveals multiple conformations of the templating 8-oxoguanine lesion
description
2012 nî lūn-bûn
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2012 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հունվարին հրատարակված գիտական հոդված
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2012年の論文
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2012年論文
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2012年論文
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2012年論文
@zh-hk
2012年論文
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2012年論文
@zh-tw
2012年论文
@wuu
name
Binary complex crystal structu ...... templating 8-oxoguanine lesion
@ast
Binary complex crystal structu ...... templating 8-oxoguanine lesion
@en
Binary complex crystal structu ...... templating 8-oxoguanine lesion
@nl
type
label
Binary complex crystal structu ...... templating 8-oxoguanine lesion
@ast
Binary complex crystal structu ...... templating 8-oxoguanine lesion
@en
Binary complex crystal structu ...... templating 8-oxoguanine lesion
@nl
prefLabel
Binary complex crystal structu ...... templating 8-oxoguanine lesion
@ast
Binary complex crystal structu ...... templating 8-oxoguanine lesion
@en
Binary complex crystal structu ...... templating 8-oxoguanine lesion
@nl
P2093
P2860
P3181
P356
P1476
Binary complex crystal structu ...... templating 8-oxoguanine lesion
@en
P2093
Charles E McKenna
David D Shock
Vinod K Batra
William A Beard
P2860
P304
P3181
P356
10.1073/PNAS.1112235108
P407
P577
2011-12-16T00:00:00Z