Oxidized nucleotide insertion by pol β confounds ligation during base excision repair.
about
Capturing a mammalian DNA polymerase extending from an oxidized nucleotide.MTH1 as a Chemotherapeutic Target: The Elephant in the Room.In vitro Assay to Measure DNA Polymerase β Nucleotide Insertion Coupled with the DNA Ligation Reaction during Base Excision Repair.Role of DNA polymerase β oxidized nucleotide insertion in DNA ligation failure.The m6A methylation perturbs the Hoogsteen pairing-guided incorporation of an oxidized nucleotide.Molecular snapshots of APE1 proofreading mismatches and removing DNA damage.Pol μ dGTP mismatch insertion opposite T coupled with ligation reveals promutagenic DNA repair intermediate
P2860
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P2860
Oxidized nucleotide insertion by pol β confounds ligation during base excision repair.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 09 January 2017
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Oxidized nucleotide insertion by pol β confounds ligation during base excision repair.
@en
Oxidized nucleotide insertion by pol β confounds ligation during base excision repair.
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type
label
Oxidized nucleotide insertion by pol β confounds ligation during base excision repair.
@en
Oxidized nucleotide insertion by pol β confounds ligation during base excision repair.
@nl
prefLabel
Oxidized nucleotide insertion by pol β confounds ligation during base excision repair.
@en
Oxidized nucleotide insertion by pol β confounds ligation during base excision repair.
@nl
P2093
P2860
P356
P1476
Oxidized nucleotide insertion by pol β confounds ligation during base excision repair.
@en
P2093
Da-Peng Dai
Donna F Stefanick
Julie K Horton
Melike Çağlayan
P2860
P2888
P356
10.1038/NCOMMS14045
P407
P577
2017-01-09T00:00:00Z