Structural and functional conservation of key domains in InsP3 and ryanodine receptors
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Cooperative bindingSingle-particle cryo-EM of calcium release channels: structural validationStructural determination of the phosphorylation domain of the ryanodine receptorDisease mutations in the ryanodine receptor N-terminal region couple to a mobile intersubunit interfaceRegulation of IP3 receptors by cyclic AMPRegulation and roles of Ca2+ stores in human spermThe Bcl-2 protein family member Bok binds to the coupling domain of inositol 1,4,5-trisphosphate receptors and protects them from proteolytic cleavageStructural insights into the human RyR2 N-terminal region involved in cardiac arrhythmiasStructure of the rabbit ryanodine receptor RyR1 at near-atomic resolution.A bead aggregation assay for detection of low-affinity protein-protein interactions reveals interactions between N-terminal domains of inositol 1,4,5-trisphosphate receptorsHydrogen gas protects IP3Rs by reducing disulfide bridges in human keratinocytes under oxidative stressStructural basis for conductance through TRIC cation channels.Toward a high-resolution structure of IP₃R channel.Aberrant calcium signaling by transglutaminase-mediated posttranslational modification of inositol 1,4,5-trisphosphate receptorsFunctional complementation of Drosophila itpr mutants by rat Itpr1.Comparative characterization of two intracellular Ca²⁺-release channels from the red flour beetle, Tribolium castaneum.Muscling in on the ryanodine receptor.Stimulation of inositol 1,4,5-trisphosphate (IP3) receptor subtypes by analogues of IP3Stimulation of inositol 1,4,5-trisphosphate (IP3) receptor subtypes by adenophostin A and its analogues.Triazolophostins: a library of novel and potent agonists of IP3 receptors.A Point Mutation in the Ubiquitin Ligase RNF170 That Causes Autosomal Dominant Sensory Ataxia Destabilizes the Protein and Impairs Inositol 1,4,5-Trisphosphate Receptor-mediated Ca2+ SignalingCrystal structures of ryanodine receptor SPRY1 and tandem-repeat domains reveal a critical FKBP12 binding determinant.Modulation of inositol 1,4,5-trisphosphate receptor type 2 channel activity by Ca2+/calmodulin-dependent protein kinase II (CaMKII)-mediated phosphorylationIdentification of functionally critical residues in the channel domain of inositol trisphosphate receptorsStructural determinants of skeletal muscle ryanodine receptor gatingGating machinery of InsP3R channels revealed by electron cryomicroscopyFragmented inositol 1,4,5-trisphosphate receptors retain tetrameric architecture and form functional Ca2+ release channels.Defining the stoichiometry of inositol 1,4,5-trisphosphate binding required to initiate Ca2+ release.CaBP1, a neuronal Ca2+ sensor protein, inhibits inositol trisphosphate receptors by clamping intersubunit interactions.N-terminal and central segments of the type 1 ryanodine receptor mediate its interaction with FK506-binding proteinsFunctional inositol 1,4,5-trisphosphate receptors assembled from concatenated homo- and heteromeric subunits.Structural insights into Ca(2+)-activated long-range allosteric channel gating of RyR1.Conformational dynamics inside amino-terminal disease hotspot of ryanodine receptorN-terminus oligomerization is conserved in intracellular calcium release channels.Ryanodine receptors: structure and function.Themes and variations in ER/SR calcium release channels: structure and function.Ryanodine receptor calcium release channels: lessons from structure-function studies.Intracellular calcium channels: inositol-1,4,5-trisphosphate receptors.Structural organization of signalling to and from IP3 receptors.Regulatory Mechanisms of Endoplasmic Reticulum Resident IP3 Receptors.
P2860
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P2860
Structural and functional conservation of key domains in InsP3 and ryanodine receptors
description
2012 nî lūn-bûn
@nan
2012 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Structural and functional conservation of key domains in InsP3 and ryanodine receptors
@ast
Structural and functional conservation of key domains in InsP3 and ryanodine receptors
@en
Structural and functional conservation of key domains in InsP3 and ryanodine receptors
@nl
type
label
Structural and functional conservation of key domains in InsP3 and ryanodine receptors
@ast
Structural and functional conservation of key domains in InsP3 and ryanodine receptors
@en
Structural and functional conservation of key domains in InsP3 and ryanodine receptors
@nl
prefLabel
Structural and functional conservation of key domains in InsP3 and ryanodine receptors
@ast
Structural and functional conservation of key domains in InsP3 and ryanodine receptors
@en
Structural and functional conservation of key domains in InsP3 and ryanodine receptors
@nl
P2093
P2860
P3181
P356
P1433
P1476
Structural and functional conservation of key domains in InsP3 and ryanodine receptors
@en
P2093
Ana M Rossi
Congmin Li
James B Ames
Min-Duk Seo
Noboru Ishiyama
Peter B Stathopulos
Philippa Dale
Samir A Khan
Saroj Velamakanni
P2860
P2888
P304
P3181
P356
10.1038/NATURE10751
P407
P577
2012-01-29T00:00:00Z
P5875
P6179
1052873446