Homology models guide discovery of diverse enzyme specificities among dipeptide epimerases in the enolase superfamily
about
Leveraging structure for enzyme function prediction: methods, opportunities, and challengesSolving nucleic acid structures by molecular replacement: examples from group II intron studiesPrediction of function for the polyprenyl transferase subgroup in the isoprenoid synthase superfamilyMolecular characterization of novel pyridoxal-5′-phosphate-dependent enzymes from the human microbiomeA comprehensive analysis of the geranylgeranylglyceryl phosphate synthase enzyme family identifies novel members and reveals mechanisms of substrate specificity and quaternary structure organizationCovalent docking predicts substrates for haloalkanoate dehalogenase superfamily phosphatasesInsights into Substrate Specificity of NlpC/P60 Cell Wall Hydrolases Containing Bacterial SH3 DomainsParallel evolution of non-homologous isofunctional enzymes in methionine biosynthesis.Catalytic site identification--a web server to identify catalytic site structural matches throughout PDB.Discovery of a novel L-lyxonate degradation pathway in Pseudomonas aeruginosa PAO1.Structure-based prediction and identification of 4-epimerization activity of phosphate sugars in class II aldolases.Protein production from the structural genomics perspective: achievements and future needs.The evolution of enzyme function in the isomerases.New insights about enzyme evolution from large scale studies of sequence and structure relationships.Participation of the Salmonella OmpD porin in the infection of RAW264.7 macrophages and BALB/c mice.Predicting the functions and specificity of triterpenoid synthases: a mechanism-based multi-intermediate docking approach.Transparency in metabolic network reconstruction enables scalable biological discoveryDASP3: identification of protein sequences belonging to functionally relevant groups.Divergent evolution of ligand binding in the o-succinylbenzoate synthase family.Predicting enzyme-substrate specificity with QM/MM methods: a case study of the stereospecificity of (D)-glucarate dehydratase.The Structure-Function Linkage DatabaseBacterial cell-wall recycling.Synthetic biology for the directed evolution of protein biocatalysts: navigating sequence space intelligently.A transient receptor potential ion channel in Chlamydomonas shares key features with sensory transduction-associated TRP channels in mammals.Comparison of topological clustering within protein networks using edge metrics that evaluate full sequence, full structure, and active site microenvironment similarity.Genomic Enzymology: Web Tools for Leveraging Protein Family Sequence-Function Space and Genome Context to Discover Novel Functions.An approach to functionally relevant clustering of the protein universe: Active site profile-based clustering of protein structures and sequences.Urocanate reductase: identification of a novel anaerobic respiratory pathway in Shewanella oneidensis MR-1.Revealing the hidden functional diversity of an enzyme family.Evolutionary and molecular foundations of multiple contemporary functions of the nitroreductase superfamily.Computational evaluation of factors governing catalytic 2-keto acid decarboxylation.Computational modelling of the binding of arachidonic acid to the human monooxygenase CYP2J2.
P2860
Q26820871-3EF5EF37-0278-490E-B7D2-D2127F1AD135Q27000781-7AD2356A-AF6C-463D-80D9-7B17316CF50CQ27676831-C7841B1E-65C1-4305-AD6C-D104C8C205CCQ27684034-DF3636EA-C8B4-4B64-A64F-07A44812E524Q27689673-2BBE5A9E-EF7D-49EE-9CE2-0FA1E843E773Q28492136-DC29160D-3227-4661-B5DE-ECACC1AC1551Q30009099-9CD279F8-59C8-4647-BBE0-3B2A6E2B8ACAQ30402739-4DDD2D51-95C6-4BF2-910E-52B83C555667Q30430641-25FF3091-C8B3-4B9C-954B-41EB6720F9C0Q33684957-C08D47E0-66D9-4F9E-B1C9-0F7D572E153BQ33694618-4FF78F21-7D11-43D5-9933-8FD86AC20593Q34174863-99A8CA63-5019-4C50-A6BA-A6A90235E2E4Q34428173-F99650EA-909F-4C22-9993-DE60D48E7CABQ34430858-9A600392-43F9-4A77-8286-8A0EAA6BE55FQ34434054-A240988D-0EA0-4A1B-805D-68432892D720Q35316916-7E346EB8-DA54-434E-8C79-3D1047FE7CC8Q35812551-838E6609-3D40-43FD-9D34-B5E41AB4E747Q36190134-42A5D4A1-2E95-4E7F-9744-EDCDDA9C2905Q37538038-9F3C2286-32B1-4132-94C3-9D82BD2A1748Q37661599-0AD3A83A-A091-44AB-BF60-D5FB5EA7ADA5Q37661971-DD66E063-72E7-48F1-BF83-32D2FAB99787Q38060821-F6ACBB55-E43F-46BF-AEDB-51D419A999FFQ38287400-558A8444-3941-4ACA-8E8B-71ADC58675CAQ38919197-957E75E5-D2A4-468B-9143-439E03D77487Q40836533-FFAEAFBA-136C-4F4D-BD62-3E8C7CF16AEFQ41506164-3D1C3C20-0A1F-46B1-9743-617F0A43A799Q42372264-102597AF-8093-47F0-89BF-15C63357C545Q42715254-FE50D62F-551F-4742-9BB2-DC9C31377AD2Q43945684-B7ABAF5B-761E-429C-88B5-FBEA6B882238Q46208740-0594E286-8C3B-4178-BDDC-8775640417D5Q47761105-820B6C8F-03EA-41CA-9356-5447F85C50FCQ48262569-EBB3CDD2-BD46-4E5F-8102-96B1A34D5D63
P2860
Homology models guide discovery of diverse enzyme specificities among dipeptide epimerases in the enolase superfamily
description
2012 nî lūn-bûn
@nan
2012 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի մարտին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Homology models guide discover ...... ses in the enolase superfamily
@ast
Homology models guide discover ...... ses in the enolase superfamily
@en
Homology models guide discover ...... ses in the enolase superfamily
@nl
type
label
Homology models guide discover ...... ses in the enolase superfamily
@ast
Homology models guide discover ...... ses in the enolase superfamily
@en
Homology models guide discover ...... ses in the enolase superfamily
@nl
prefLabel
Homology models guide discover ...... ses in the enolase superfamily
@ast
Homology models guide discover ...... ses in the enolase superfamily
@en
Homology models guide discover ...... ses in the enolase superfamily
@nl
P2093
P2860
P50
P3181
P356
P1476
Homology models guide discover ...... ses in the enolase superfamily
@en
P2093
Alexander A Fedorov
Ayano Sakai
Brandan Hillerich
Chakrapani Kalyanaraman
Elena V Fedorov
John A Gerlt
Matthew W Vetting
Ronald Seidel
Satish K Nair
P2860
P304
P3181
P356
10.1073/PNAS.1112081109
P407
P50
P577
2012-03-13T00:00:00Z