Identification of a small molecule with activity against drug-resistant and persistent tuberculosis - Wikidata - awgldk - TriplyDB

Identification of a small molecule with activity against drug-resistant and persistent tuberculosis

Identification of a small molecule with activity against drug-resistant and persistent tuberculosis

http://www.wikidata.org/entity/Q27678663

about

New agents for the treatment of drug-resistant Mycobacterium tuberculosis The application of tetracyclineregulated gene expression systems in the validation of novel drug targets in Mycobacterium tuberculosis Tuberculosis drug discovery in the post-post-genomic era Structure, dynamics, and interaction of Mycobacterium tuberculosis (Mtb) DprE1 and DprE2 examined by molecular modeling, simulation, and electrostatic studies Learning from the past for TB drug discovery in the future THPP target assignment reveals EchA6 as an essential fatty acid shuttle in mycobacteria Biochemical and structural characterization of mycobacterial aspartyl-tRNA synthetase AspS, a promising TB drug target Mycobacterial phylogenomics: an enhanced method for gene turnover analysis reveals uneven levels of gene gain and loss among species and gene families Phenotypic and genomic comparison of Mycobacterium aurum and surrogate model species to Mycobacterium tuberculosis: implications for drug discovery.1,4-azaindole, a potential drug candidate for treatment of tuberculosis.Noncanonical SMC protein in Mycobacterium smegmatis restricts maintenance of Mycobacterium fortuitum plasmids.The mycobacterial cell envelope-lipids The cell envelope glycoconjugates of Mycobacterium tuberculosis Identification of novel inhibitors of nonreplicating Mycobacterium tuberculosis using a carbon starvation model Genetic Approaches to Facilitate Antibacterial Drug Development.Design, Syntheses, and Anti-TB Activity of 1,3-Benzothiazinone Azide and Click Chemistry Products Inspired by BTZ043.A novel therapeutic strategy of lipidated promiscuous peptide against Mycobacterium tuberculosis by eliciting Th1 and Th17 immunity of host Mechanistic Investigation of cPMP Synthase in Molybdenum Cofactor Biosynthesis Using an Uncleavable Substrate Analogue Thiol reductive stress induces cellulose-anchored biofilm formation in Mycobacterium tuberculosis.Benzothiazinethione is a potent preclinical candidate for the treatment of drug-resistant tuberculosis Novel Cephalosporins Selectively Active on Nonreplicating Mycobacterium tuberculosis.N-methylation of a bactericidal compound as a resistance mechanism in Mycobacterium tuberculosis.Stimulation through CD40 and TLR-4 Is an Effective Host Directed Therapy against Mycobacterium tuberculosis.The DprE1 enzyme, one of the most vulnerable targets of Mycobacterium tuberculosis.MmpL3 a potential new target for development of novel anti-tuberculosis drugs.Trends in discovery of new drugs for tuberculosis therapy.The future for early-stage tuberculosis drug discovery The Mycobacterial Cell Wall--Peptidoglycan and Arabinogalactan.Pili of Mycobacterium tuberculosis: current knowledge and future prospects.The anti-tuberculosis agents under development and the challenges ahead.Identification of Better Pharmacokinetic Benzothiazinone Derivatives as New Antitubercular Agents.Characterization of DprE1-Mediated Benzothiazinone Resistance in Mycobacterium tuberculosis.Inhibiting Mycobacterium tuberculosis within and without.Targeting Phenotypically Tolerant Mycobacterium tuberculosis.News on therapeutic management of MDR-tuberculosis: a literature review.Vaccines Directed Against Microorganisms or Their Products Present During Biofilm Lifestyle: Can We Make a Translation as a Broad Biological Model to Tuberculosis?Nitroarenes as Antitubercular Agents: Stereoelectronic Modulation to Mitigate Mutagenicity.Polyketide Quinones Are Alternate Intermediate Electron Carriers during Mycobacterial Respiration in Oxygen-Deficient Niches.Visualization of the Charcoal Agar Resazurin Assay for Semi-quantitative, Medium-throughput Enumeration of Mycobacteria.The Cyclic Di-GMP Phosphodiesterase Gene Rv1357c/BCG1419c Affects BCG Pellicle Production and In Vivo Maintenance.

P2860

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P2860

Identification of a small molecule with activity against drug-resistant and persistent tuberculosis

http://www.wikidata.org/entity/Q27678663

description

2013 nî lūn-bûn

@nan

2013 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2013 թվականի հուլիսին հրատարակված գիտական հոդված

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年论文

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name

Identification of a small mole ...... nt and persistent tuberculosis

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Identification of a small mole ...... nt and persistent tuberculosis

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Identification of a small mole ...... nt and persistent tuberculosis

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type

label

Identification of a small mole ...... nt and persistent tuberculosis

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Identification of a small mole ...... nt and persistent tuberculosis

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Identification of a small mole ...... nt and persistent tuberculosis

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prefLabel

Identification of a small mole ...... nt and persistent tuberculosis

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Identification of a small mole ...... nt and persistent tuberculosis

@en

Identification of a small mole ...... nt and persistent tuberculosis

@nl

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PNAS.1309171110

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Proceedings of the National Academy of Sciences of the United States of America

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Identification of a small mole ...... nt and persistent tuberculosis

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P2093

Arnab K Chatterjee

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Claudia Trefzer

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Dhinakaran Sambandan

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Feng Wang

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Insha Ahmad

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Jianing Wang

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John Kim

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John R Walker

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Katarina Mikusova

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Khisi E Mdluli

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P2860

PHENIX: a comprehensive Python-based system for macromolecular structure solution

Structural basis of inhibition of Mycobacterium tuberculosis DprE1 by benzothiazinone inhibitors

REFMAC5 for the refinement of macromolecular crystal structures

Phasercrystallographic software

Features and development of Coot

An in vitro model for sequential study of shiftdown of Mycobacterium tuberculosis through two stages of nonreplicating persistence

A novel in vitro multiple-stress dormancy model for Mycobacterium tuberculosis generates a lipid-loaded, drug-tolerant, dormant pathogen

Benzothiazinones kill Mycobacterium tuberculosis by blocking arabinan synthesis

Functional analysis of molybdopterin biosynthesis in mycobacteria identifies a fused molybdopterin synthase in Mycobacterium tuberculosis

The roles of the nitrate reductase NarGHJI, the nitrite reductase NirBD and the response regulator GlnR in nitrate assimilation of Mycobacterium tuberculosis

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E2510-7

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27

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110

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Klaus Fütterer

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2013-06-17T00:00:00Z

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239945682

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23776209

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Akafuba bulwadde

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3703973

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