A Designed Functional Metalloenzyme that Reduces O2 to H2O with Over One Thousand Turnovers
about
Three toxic gases meet in the mitochondriaProtein design: toward functional metalloenzymesSystematic Tuning of Heme Redox Potentials and Its Effects on O 2 Reduction Rates in a Designed Oxidase in MyoglobinRational design of heterodimeric protein using domain swapping for myoglobinHow a novel tyrosine-heme cross-link fine-tunes the structure and functions of heme proteins: a direct comparitive study of L29H/F43Y myoglobinElementary tetrahelical protein design for diverse oxidoreductase functions.Peroxidase Activity of a c-Type Cytochrome b5 in the Non-Native State is Comparable to that of Native Peroxidases.Computational strategies for the design of new enzymatic functionsSignificant Improvement of Oxidase Activity through the Genetic Incorporation of a Redox-active Unnatural Amino Acid.A biosynthetic model of cytochrome c oxidase as an electrocatalyst for oxygen reduction.Defining the role of tyrosine and rational tuning of oxidase activity by genetic incorporation of unnatural tyrosine analogs.A Designed Metalloenzyme Achieving the Catalytic Rate of a Native Enzyme.Recent advances in biosynthetic modeling of nitric oxide reductases and insights gained from nuclear resonance vibrational and other spectroscopic studies.Spectroscopic and Crystallographic Evidence for the Role of a Water-Containing H-Bond Network in Oxidase Activity of an Engineered Myoglobin.An engineered heme-copper center in myoglobin: CO migration and binding.Designing functional metalloproteins: from structural to catalytic metal sites.Rational Design of Dual Active Sites in a Single Protein Scaffold: A Case Study of Heme Protein in Myoglobin.Design of Heteronuclear Metalloenzymes.Direct EPR observation of a tyrosyl radical in a functional oxidase model in myoglobin during both H2O2 and O2 reactions.Rational heme protein design: all roads lead to Rome.Artificial metalloenzymes constructed from hierarchically-assembled proteins.Metalloenzyme design and engineering through strategic modifications of native protein scaffolds.Why copper is preferred over iron for oxygen activation and reduction in haem-copper oxidases.Using Biosynthetic Models of Heme-Copper Oxidase and Nitric Oxide Reductase in Myoglobin to Elucidate Structural Features Responsible for Enzymatic Activities.Design and engineering of artificial oxygen-activating metalloenzymes.Activation of dioxygen by copper metalloproteins and insights from model complexes.Improving artificial metalloenzymes' activity by optimizing electron transfer.Manganese and Cobalt in the Nonheme-Metal-Binding Site of a Biosynthetic Model of Heme-Copper Oxidase Superfamily Confer Oxidase Activity through Redox-Inactive Mechanism.Oxygen Activation and Radical Transformations in Heme Proteins and Metalloporphyrins.Design of artificial metalloproteins/metalloenzymes by tuning noncovalent interactions.Designed Heme-Cage β-Sheet Miniproteins.Insights Into How Heme Reduction Potentials Modulate Enzymatic Activities of a Myoglobin-based Functional Oxidase.Photo-induced hydrogen production in a helical peptide incorporating a [FeFe] hydrogenase active site mimic.PrefaceBiosynthetic approach to modeling and understanding metalloproteins using unnatural amino acidsFunctional tuning and expanding of myoglobin by rational protein design
P2860
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P2860
A Designed Functional Metalloenzyme that Reduces O2 to H2O with Over One Thousand Turnovers
description
2012 nî lūn-bûn
@nan
2012 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
A Designed Functional Metalloe ...... th Over One Thousand Turnovers
@ast
A Designed Functional Metalloe ...... th Over One Thousand Turnovers
@en
A Designed Functional Metalloe ...... th Over One Thousand Turnovers
@nl
type
label
A Designed Functional Metalloe ...... th Over One Thousand Turnovers
@ast
A Designed Functional Metalloe ...... th Over One Thousand Turnovers
@en
A Designed Functional Metalloe ...... th Over One Thousand Turnovers
@nl
prefLabel
A Designed Functional Metalloe ...... th Over One Thousand Turnovers
@ast
A Designed Functional Metalloe ...... th Over One Thousand Turnovers
@en
A Designed Functional Metalloe ...... th Over One Thousand Turnovers
@nl
P2093
P2860
P50
P356
P1476
A Designed Functional Metalloe ...... th Over One Thousand Turnovers
@en
P2093
Arnab Mukherjee
Howard Robinson
Igor D Petrik
Natasha Yeung
Yi-Gui Gao
P2860
P304
P356
10.1002/ANIE.201201981
P407
P577
2012-06-04T00:00:00Z