Substituted pyrrolo[2,3-d]pyrimidines as Cryptosporidium hominis thymidylate synthase inhibitors
about
Understanding the molecular mechanism of substrate channeling and domain communication in protozoal bifunctional TS-DHFR.A nanotherapy strategy significantly enhances anticryptosporidial activity of an inhibitor of bifunctional thymidylate synthase-dihydrofolate reductase from Cryptosporidium.Structural studies provide clues for analog design of specific inhibitors of Cryptosporidium hominis thymidylate synthase-dihydrofolate reductase.
P2860
Substituted pyrrolo[2,3-d]pyrimidines as Cryptosporidium hominis thymidylate synthase inhibitors
description
2013 nî lūn-bûn
@nan
2013 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Substituted pyrrolo[2,3-d]pyri ...... hymidylate synthase inhibitors
@ast
Substituted pyrrolo[2,3-d]pyri ...... hymidylate synthase inhibitors
@en
Substituted pyrrolo[2,3-d]pyri ...... hymidylate synthase inhibitors
@nl
type
label
Substituted pyrrolo[2,3-d]pyri ...... hymidylate synthase inhibitors
@ast
Substituted pyrrolo[2,3-d]pyri ...... hymidylate synthase inhibitors
@en
Substituted pyrrolo[2,3-d]pyri ...... hymidylate synthase inhibitors
@nl
prefLabel
Substituted pyrrolo[2,3-d]pyri ...... hymidylate synthase inhibitors
@ast
Substituted pyrrolo[2,3-d]pyri ...... hymidylate synthase inhibitors
@en
Substituted pyrrolo[2,3-d]pyri ...... hymidylate synthase inhibitors
@nl
P2093
P2860
P921
P1476
Substituted pyrrolo[2,3-d]pyri ...... hymidylate synthase inhibitors
@en
P2093
Aleem Gangjee
Hitesh K Jain
Karen S Anderson
Kathleen M Frey
Vidya P Kumar
Yiqiang Wang
P2860
P304
P356
10.1016/J.BMCL.2013.07.037
P407
P577
2013-10-01T00:00:00Z