Structure and Topology of the Huntingtin 1–17 Membrane Anchor by a Combined Solution and Solid-State NMR Approach
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A huntingtin-mediated fast stress response halting endosomal trafficking is defective in Huntington's disease.Simultaneous acquisition of 2D and 3D solid-state NMR experiments for sequential assignment of oriented membrane protein samplesCholesterol Modifies Huntingtin Binding to, Disruption of, and Aggregation on Lipid Membranes.Membrane interactions of phylloseptin-1, -2, and -3 peptides by oriented solid-state NMR spectroscopy.Free-Energy Landscape of the Amino-Terminal Fragment of Huntingtin in Aqueous SolutionPolyglutamine amyloid core boundaries and flanking domain dynamics in huntingtin fragment fibrils determined by solid-state nuclear magnetic resonance.Simplifying solid-state NMR spectra for biophysical studies on membrane proteins: selective targeting of sites and interactions.Probing the Huntingtin 1-17 membrane anchor on a phospholipid bilayer by using all-atom simulationsPolyglutamine- and temperature-dependent conformational rigidity in mutant huntingtin revealed by immunoassays and circular dichroism spectroscopyThe emerging role of the first 17 amino acids of huntingtin in Huntington's diseaseHuntingtin N-Terminal Monomeric and Multimeric Structures Destabilized by Covalent Modification of Heteroatomic Residues.α-Synuclein and huntingtin exon 1 amyloid fibrils bind laterally to the cellular membrane.Acetylation within the First 17 Residues of Huntingtin Exon 1 Alters Aggregation and Lipid Binding.On the design of supramolecular assemblies made of peptides and lipid bilayers.Membrane topologies of the PGLa antimicrobial peptide and a transmembrane anchor sequence by Dynamic Nuclear Polarization/solid-state NMR spectroscopy.Emerging β-Sheet Rich Conformations in Supercompact Huntingtin Exon-1 Mutant Structures.Proteins Containing Expanded Polyglutamine Tracts and Neurodegenerative Disease.Huntington's Disease: Calcium Dyshomeostasis and Pathology ModelspH-Dependent Membrane Interactions of the Histidine-Rich Cell-Penetrating Peptide LAH4-L1.Structure of a single-chain Fv bound to the 17 N-terminal residues of huntingtin provides insights into pathogenic amyloid formation and suppression.Huntingtin N17 domain is a reactive oxygen species sensor regulating huntingtin phosphorylation and localization.Investigation of membrane penetration depth and interactions of the amino-terminal domain of huntingtin: refined analysis by tryptophan fluorescence measurement.Lysine residues in the N-terminal huntingtin amphipathic α-helix play a key role in peptide aggregation.Atomistic mechanisms of huntingtin N-terminal fragment insertion on a phospholipid bilayer revealed by molecular dynamics simulations.The 17-residue-long N terminus in huntingtin controls step-wise aggregation in solution and on membranes via different mechanisms.Dynamic Nuclear Polarization/Solid-State NMR Spectroscopy of Membrane Polypeptides: Free-Radical Optimization for Matrix-Free Lipid Bilayer Samples.Sphingomyelin and GM1 Influence Huntingtin Binding to, Disruption of, and Aggregation on Lipid Membranes.Assembly of Huntingtin headpiece into α-helical bundles.
P2860
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P2860
Structure and Topology of the Huntingtin 1–17 Membrane Anchor by a Combined Solution and Solid-State NMR Approach
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2013 nî lūn-bûn
@nan
2013 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2013年の論文
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2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Structure and Topology of the ...... n and Solid-State NMR Approach
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Structure and Topology of the ...... n and Solid-State NMR Approach
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Structure and Topology of the ...... n and Solid-State NMR Approach
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Structure and Topology of the ...... n and Solid-State NMR Approach
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Structure and Topology of the ...... n and Solid-State NMR Approach
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Structure and Topology of the ...... n and Solid-State NMR Approach
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Structure and Topology of the ...... n and Solid-State NMR Approach
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Structure and Topology of the ...... n and Solid-State NMR Approach
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Structure and Topology of the ...... n and Solid-State NMR Approach
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P2093
P2860
P1433
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Structure and Topology of the ...... n and Solid-State NMR Approach
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P2093
Burkhard Bechinger
Evgeniy S Salnikov
Matthias Michalek
P2860
P304
P356
10.1016/J.BPJ.2013.06.030
P407
P577
2013-08-06T00:00:00Z