Polyglutamine- and temperature-dependent conformational rigidity in mutant huntingtin revealed by immunoassays and circular dichroism spectroscopy

Polyglutamine- and temperature-dependent conformational rigidity in mutant huntingtin revealed by immunoassays and circular dichroism spectroscopy

Item
http://www.wikidata.org/entity/Q35479250
Structural Mechanisms of Mutant Huntingtin Aggregation Suppression by the Synthetic Chaperonin-like CCT5 Complex Explained by Cryoelectron Tomography.An Intein-based Strategy for the Production of Tag-free Huntingtin Exon 1 Proteins Enables New Insights into the Polyglutamine Dependence of Httex1 Aggregation and Fibril FormationAnti-PolyQ Antibodies Recognize a Short PolyQ Stretch in Both Normal and Mutant Huntingtin Exon 1.Solid-State Nuclear Magnetic Resonance on the Static and Dynamic Domains of Huntingtin Exon-1 Fibrils.Huntingtin's spherical solenoid structure enables polyglutamine tract-dependent modulation of its structure and function.Emerging β-Sheet Rich Conformations in Supercompact Huntingtin Exon-1 Mutant Structures.Polyglutamine expansion affects huntingtin conformation in multiple Huntington's disease models.Correction: polyglutamine- and temperature-dependent conformational rigidity in mutant huntingtin revealed by immunoassays and circular dichroism spectroscopy.Phosphorylation of huntingtin at residue T3 is decreased in Huntington's disease and modulates mutant huntingtin protein conformation.The 17-residue-long N terminus in huntingtin controls step-wise aggregation in solution and on membranes via different mechanisms.Design Principles of Peptide Based Self-Assembled Nanomaterials.Validation of Ultrasensitive Mutant Huntingtin Detection in Human Cerebrospinal Fluid by Single Molecule Counting Immunoassay.The COOH-terminal domain of huntingtin interacts with RhoGEF kalirin and modulates cell survival.
P2860

Polyglutamine- and temperature-dependent conformational rigidity in mutant huntingtin revealed by immunoassays and circular dichroism spectroscopy

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http://www.wikidata.org/entity/Q35479250
description
2014 nî lūn-bûn
@nan
2014 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年学术文章
@wuu
2014年学术文章
@zh-cn
2014年学术文章
@zh-hans
2014年学术文章
@zh-my
2014年学术文章
@zh-sg
2014年學術文章
@yue
name
Polyglutamine- and temperature ...... ircular dichroism spectroscopy
@ast
Polyglutamine- and temperature ...... ircular dichroism spectroscopy
@en
type
label
Polyglutamine- and temperature ...... ircular dichroism spectroscopy
@ast
Polyglutamine- and temperature ...... ircular dichroism spectroscopy
@en
prefLabel
Polyglutamine- and temperature ...... ircular dichroism spectroscopy
@ast
Polyglutamine- and temperature ...... ircular dichroism spectroscopy
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P932
P356
P1433
P1476
Polyglutamine- and temperature ...... ircular dichroism spectroscopy
@en
P2093
P2860
P304
P31
P356
10.1371/JOURNAL.PONE.0112262
P407
P433
P478
P50
P577
P5875
P698
P932