Dimeric Structure of Pseudokinase RNase L Bound to 2-5A Reveals a Basis for Interferon-Induced Antiviral Activity
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The Roles of RNase-L in Antimicrobial Immunity and the Cytoskeleton-Associated Innate ResponseStructure of Human RNase L Reveals the Basis for Regulated RNA Decay in the IFN ResponseThe structure of the Pan2-Pan3 core complex reveals cross-talk between deadenylase and pseudokinaseCrystal structure of the mouse hepatitis virus ns2 phosphodiesterase domain that antagonizes RNase L activationCharacterization of Novel Ribosome-Associated Endoribonuclease SLFN14 from Rabbit ReticulocytesPseudokinases: update on their functions and evaluation as new drug targets.Molecular mechanisms of human IRE1 activation through dimerization and ligand bindingRNase L targets distinct sites in influenza A virus RNAs.Structure of Fam20A reveals a pseudokinase featuring a unique disulfide pattern and inverted ATP-bindingThe CDI toxin of Yersinia kristensenii is a novel bacterial member of the RNase A superfamily.Viral phosphodiesterases that antagonize double-stranded RNA signaling to RNase L by degrading 2-5ARNase L interacts with Filamin A to regulate actin dynamics and barrier function for viral entryRNase L attenuates mitogen-stimulated gene expression via transcriptional and post-transcriptional mechanisms to limit the proliferative responseStructural biology of innate immunity.OASes and STING: adaptive evolution in concertStructural basis for 2'-5'-oligoadenylate binding and enzyme activity of a viral RNase L antagonist.Structural Basis for the Non-catalytic Functions of Protein Kinases.Structural basis for the endoribonuclease activity of the type III-A CRISPR-associated protein Csm6Activation of RNase L is dependent on OAS3 expression during infection with diverse human virusesMiddle East Respiratory Syndrome Coronavirus NS4b Protein Inhibits Host RNase L Activation.RNase L Suppresses Androgen Receptor Signaling, Cell Migration and Matrix Metalloproteinase Activity in Prostate Cancer Cells.OAS proteins and cGAS: unifying concepts in sensing and responding to cytosolic nucleic acids.The 2'-5'-oligoadenylate synthetase 3 enzyme potently synthesizes the 2'-5'-oligoadenylates required for RNase L activation.Rapid RNase L-Driven Arrest of Protein Synthesis in the dsRNA Response without Degradation of Translation Machinery.Nucleotide-binding mechanisms in pseudokinases.Evolutionary adaptation revealed by comparative genome analysis of woolly mammoths and elephants.RNase L activates the NLRP3 inflammasome during viral infections.Mitochondrial C11orf83 is a potent Antiviral Protein Independent of interferon production.Functional evolution of the OAS1 viral sensor: Insights from old world primates.Crystal structure of the C-terminal 2',5'-phosphodiesterase domain of group A rotavirus protein VP3.Curcumin, a natural antioxidant, acts as a noncompetitive inhibitor of human RNase L in presence of its cofactor 2-5A in vitro.Grc3 programs the essential endoribonuclease Las1 for specific RNA cleavage.Nuclease integrated kinase super assemblies (NiKs) and their role in RNA processing.Characterization of the Molecular Crosstalk within the Essential Grc3/Las1 pre-rRNA Processing Complex.Pharmacological targeting of MYC-regulated IRE1/XBP1 pathway suppresses MYC-driven breast cancer.A novel mechanism of RNase L inhibition: Theiler's virus L* protein prevents 2-5A from binding to RNase L.A human cellular noncoding RNA activates the antiviral protein 2'-5'-oligoadenylate synthetase 1
P2860
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P2860
Dimeric Structure of Pseudokinase RNase L Bound to 2-5A Reveals a Basis for Interferon-Induced Antiviral Activity
description
2014 nî lūn-bûn
@nan
2014 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Dimeric Structure of Pseudokin ...... ron-Induced Antiviral Activity
@ast
Dimeric Structure of Pseudokin ...... ron-Induced Antiviral Activity
@en
Dimeric Structure of Pseudokin ...... ron-Induced Antiviral Activity
@en-gb
Dimeric Structure of Pseudokin ...... ron-Induced Antiviral Activity
@nl
type
label
Dimeric Structure of Pseudokin ...... ron-Induced Antiviral Activity
@ast
Dimeric Structure of Pseudokin ...... ron-Induced Antiviral Activity
@en
Dimeric Structure of Pseudokin ...... ron-Induced Antiviral Activity
@en-gb
Dimeric Structure of Pseudokin ...... ron-Induced Antiviral Activity
@nl
prefLabel
Dimeric Structure of Pseudokin ...... ron-Induced Antiviral Activity
@ast
Dimeric Structure of Pseudokin ...... ron-Induced Antiviral Activity
@en
Dimeric Structure of Pseudokin ...... ron-Induced Antiviral Activity
@en-gb
Dimeric Structure of Pseudokin ...... ron-Induced Antiviral Activity
@nl
P2093
P2860
P50
P3181
P1433
P1476
Dimeric Structure of Pseudokin ...... ron-Induced Antiviral Activity
@en
P2093
Alba Guarné
Andrey A Perelygin
Beihua Dong
Daniel Y L Mao
Igor Kourinov
Leo C K Wan
Manisha Talukdar
Margo A Brinton
Monica C Pillon
P2860
P304
P3181
P356
10.1016/J.MOLCEL.2013.12.025
P577
2014-01-23T00:00:00Z