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Analysis of substrate specificity and cyclin Y binding of PCTAIRE-1 kinaseThe linear ubiquitin-specific deubiquitinase gumby regulates angiogenesisNon-canonical inhibition of DNA damage-dependent ubiquitination by OTUB1Non-canonical interaction of phosphoinositides with pleckstrin homology domains of Tiam1 and ArhGAP9Structural basis and sequence rules for substrate recognition by Tankyrase explain the basis for cherubism diseaseCCM3/PDCD10 heterodimerizes with germinal center kinase III (GCKIII) proteins using a mechanism analogous to CCM3 homodimerizationProtein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactionsA PP2A phosphatase high density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous malformation 3 (CCM3) proteinNedd4-1 binds and ubiquitylates activated FGFR1 to control its endocytosis and functionDetermination of the Plk4/Sak consensus phosphorylation motif using peptide spots arraysAutoinhibition of the HECT-type ubiquitin ligase Smurf2 through its C2 domainPotent and selective inhibitors of the inositol-requiring enzyme 1 endoribonucleaseX-ray crystal structure and functional analysis of vaccinia virus K3L reveals molecular determinants for PKR subversion and substrate recognitionThe Sak polo-box comprises a structural domain sufficient for mitotic subcellular localizationStructural basis for phosphodependent substrate selection and orientation by the SCFCdc4 ubiquitin ligaseStructure and mechanism of action of the hydroxy–aryl–aldehyde class of IRE1 endoribonuclease inhibitorsBone recognition mechanism of porcine osteocalcin from crystal structureConformational instability of the MARK3 UBA domain compromises ubiquitin recognition and promotes interaction with the adjacent kinase domainStructure of the Dual Enzyme Ire1 Reveals the Basis for Catalysis and Regulation in Nonconventional RNA SplicingDcn1 functions as a scaffold-type E3 ligase for cullin neddylationCNK and HYP form a discrete dimer by their SAM domains to mediate RAF kinase signalingAtomic Structure of the KEOPS Complex: An Ancient Protein Kinase-Containing Molecular MachineStructural studies of FF domains of the transcription factor CA150 provide insights into the organization of FF domain tandem arraysFlavonol Activation Defines an Unanticipated Ligand-Binding Site in the Kinase-RNase Domain of IRE1An allosteric inhibitor of substrate recognition by the SCFCdc4 ubiquitin ligaseAn allosteric inhibitor of the human Cdc34 ubiquitin-conjugating enzymeStructural basis for specificity of TGFβ family receptor small molecule inhibitorsA Strategy for Modulation of Enzymes in the Ubiquitin SystemOTUB1 Co-opts Lys48-Linked Ubiquitin Recognition to Suppress E2 Enzyme FunctionComposite low affinity interactions dictate recognition of the cyclin-dependent kinase inhibitor Sic1 by the SCFCdc4 ubiquitin ligaseReconstitution and characterization of eukaryotic N6-threonylcarbamoylation of tRNA using a minimal enzyme systemInhibitors that stabilize a closed RAF kinase domain conformation induce dimerizationStructure of an SspH1-PKN1 Complex Reveals the Basis for Host Substrate Recognition and Mechanism of Activation for a Bacterial E3 Ubiquitin LigaseDimeric Structure of Pseudokinase RNase L Bound to 2-5A Reveals a Basis for Interferon-Induced Antiviral ActivityStructural basis for the recruitment of glycogen synthase by glycogeninStructural basis of Rad53 kinase activation by dimerization and activation segment exchangeCrystal structure of a BRAF kinase domain monomer explains basis for allosteric regulationStructural and functional characterization of KEOPS dimerization by Pcc1 and its role in t6A biosynthesisThe structural basis of modified nucleosome recognition by 53BP1
P50
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P50
description
hulumtues
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Frank Sicheri
@ast
Frank Sicheri
@en
Frank Sicheri
@es
Frank Sicheri
@sl
type
label
Frank Sicheri
@ast
Frank Sicheri
@en
Frank Sicheri
@es
Frank Sicheri
@sl
prefLabel
Frank Sicheri
@ast
Frank Sicheri
@en
Frank Sicheri
@es
Frank Sicheri
@sl