Synthesis of carba-NAD and the structures of its ternary complexes with SIRT3 and SIRT5

Synthesis of carba-NAD and the structures of its ternary complexes with SIRT3 and SIRT5

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http://www.wikidata.org/entity/Q27681883
Structural and Functional Analysis of Human SIRT1Structures of human sirtuin 3 complexes with ADP-ribose and with carba-NAD+ and SRT1720: binding details and inhibition mechanismSelective Sirt2 inhibition by ligand-induced rearrangement of the active site.Synthesis of novel N-cyclopentenyl-lactams using the Aubé reaction.Using mitochondrial sirtuins as drug targets: disease implications and available compounds.Metabolic mechanisms of epigenetic regulation.New assays and approaches for discovery and design of Sirtuin modulators.Deacylation Mechanism by SIRT2 Revealed in the 1'-SH-2'-O-Myristoyl Intermediate Structure.Seeding for sirtuins: microseed matrix seeding to obtain crystals of human Sirt3 and Sirt2 suitable for soaking.Sirtuin 5: a review of structure, known inhibitors and clues for developing new inhibitors.The Current State of NAD(+) -Dependent Histone Deacetylases (Sirtuins) as Novel Therapeutic Targets.Crystallographic structure of a small molecule SIRT1 activator-enzyme complex.NAD+ analog reveals PARP-1 substrate-blocking mechanism and allosteric communication from catalytic center to DNA-binding domains.Biophysical characterization of hit compounds for mechanism-based enzyme activation.14-3-3 proteins activate Pseudomonas exotoxins-S and -T by chaperoning a hydrophobic surface
P2860

Synthesis of carba-NAD and the structures of its ternary complexes with SIRT3 and SIRT5

Item
http://www.wikidata.org/entity/Q27681883
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2012 nî lūn-bûn
@nan
2012 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Synthesis of carba-NAD and the structures of its ternary complexes with SIRT3 and SIRT5
@ast
Synthesis of carba-NAD and the structures of its ternary complexes with SIRT3 and SIRT5
@en
Synthesis of carba-NAD and the structures of its ternary complexes with SIRT3 and SIRT5
@nl
type
label
Synthesis of carba-NAD and the structures of its ternary complexes with SIRT3 and SIRT5
@ast
Synthesis of carba-NAD and the structures of its ternary complexes with SIRT3 and SIRT5
@en
Synthesis of carba-NAD and the structures of its ternary complexes with SIRT3 and SIRT5
@nl
prefLabel
Synthesis of carba-NAD and the structures of its ternary complexes with SIRT3 and SIRT5
@ast
Synthesis of carba-NAD and the structures of its ternary complexes with SIRT3 and SIRT5
@en
Synthesis of carba-NAD and the structures of its ternary complexes with SIRT3 and SIRT5
@nl
P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P356
P1433
P1476
Synthesis of carba-NAD and the structures of its ternary complexes with SIRT3 and SIRT5
@en
P2093
P304
P31
P356
P407
P433
P478
P577
P5875
P698